Journals / Adli Tıp Dergisi / 2013 / Cilt: 27 - Sayı: 1

Choıces of bıologıcal sample and analytıcal method ın forensıc toxıcology analyses

Adli toksikoloji analizlerinde biyolojik örnek ve analitik yöntem seçimleri

Pages
44–53
Publication Date
2022-10-11
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The purpose of our study is to ge- nerate awareness, for the cases about which forensic toxicological and pharmacological assessment is going to be performed, on issu- es of the importance of choosing expedient biological samples- analytical methods, synchroniza- tion of forensic toxicology-phar- macology-analytical toxicology, impossibility of solving a forensic toxicology case in an accurate and reliable way without standardiza- tion of laboratories and validation of the methods used in analytical toxicology.

📌 3 Key Takeaways

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Objective & Hypothesis:Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Mersin University , Mersin, Tur- kiye Investigation of chemical subs- tances in biological samples with analytical methods and interpre- tation of their results as a positive evidence is important for forensic sciences.
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Key Findings & Data:Accordingly, for a cor- rect forensic medical evaluation and interpretation of cases, to- xicological and pharmacological investigations have also an im- portant role as well as other diag- nostic methods.
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Conclusion & Impact:The purpose of our study is to ge- nerate awareness, for the cases about which forensic toxicological and pharmacological assessment is going to be performed, on issu- es of the importance of choosing expedient biological samples- analytical methods, synchroniza- tion of forensic toxicology-phar- macology-analytical toxicology, impossibility of solving a forensic toxicology case in an accurate and reliable way without standardiza- tion of laboratories and validation of the methods used in analytical toxicology.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Mersin University , Mersin, Tur- kiye Investigation of chemical subs- tances in biological samples with analytical methods and interpre- tation of their results as a positive evidence is important for forensic sciences. Accordingly, for a cor- rect forensic medical evaluation and interpretation of cases, to- xicological and pharmacological investigations have also an im- portant role as well as other diag- nostic methods. For this purpose, maintaining a systematic appro- ach is a stage which should be ta- ken into consideration carefully in terms of the quality and reliability of the analytical results. In this study, after a review of li- terature about the antemortem- postmortem biological samples used in forensic toxicology prac- tice, the appropriate methods to obtain, to store these samples, to send them to the laboratory, ne- cessary conditions for the sample preparation, and equipment-met- hods used in analysis, obtained data has been collected together and presented. The purpose of our study is to ge- nerate awareness, for the cases about which forensic toxicological and pharmacological assessment is going to be performed, on issu- es of the importance of choosing expedient biological samples- analytical methods, synchroniza- tion of forensic toxicology-phar- macology-analytical toxicology, impossibility of solving a forensic toxicology case in an accurate and reliable way without standardiza- tion of laboratories and validation of the methods used in analytical toxicology.

Özet

Biyolojik örneklerde bir kimya- sal maddenin analitik yöntem- lerle araştırılması ve sonucun pozitif bir delil olarak yorum- lanması adli bilimler için önem taşımaktadır. Buna bağlı olarak genel adli tıp uygulamalarına bakıldığında, gerek klinik mua- yenelerde, gerekse postmortem incelemelerde olguların değer- lendirilmesi ve doğru bir şekil- de yorumlanabilmesi için diğer inceleme yöntemlerinin yanı sıra toksikolojik ve farmakolojik incelemeler de önemli bir yer tutmaktadır. Bu amaçla yapılan analizlerde izlenecek sistematik yol, analitik sonuçların kalitesi ve güvenilirliği açısından dikkat- le göz önüne alınması gereken bir aşamadır. Bu çalışmada, adli toksikoloji çalışmalarında kullanılan ante- mortem-postmortem biyolojik örnekler, bu örneklerin uygun yöntemlerle alınması, saklan- ması, laboratuara gönderilme- si, analiz amaçlı hazırlanması için gerekli koşullar, analizlerde kullanılan cihazlar-yöntemler hakkında literatür taraması ya- pılmış ve elde edilen veriler der- lenerek sunulmuştur. Çalışmamızın amacı, adli toksi- kolojik ve farmakolojik değer- lendirmesi yapılacak olgular için, amaca uygun biyolojik ör- nekleri-analitik yöntemleri seç- menin önemi, adli toksikoloji- farmakoloji-analitik toksikoloji birlikteliği, analitik toksikolojide kullanılan yöntemlerin validas- yonu ve laboratuarların stan- dardizasyonu sağlanmadan adli toksikolojide bir olgunun doğru ve güvenilir bir şekilde aydınla- tılmasının mümkün olamayaca- ğı konularında farkındalık yarat- maktır.

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Cite This Article

BATTAL, D. (2022). Choıces of bıologıcal sample and analytıcal method ın forensıc toxıcology analyses. Adli Tıp Dergisi, Cilt: 27 - Sayı: 1, 44–53. https://ajindex.com/articles/428776

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