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Journals / Molecular Imaging and Radionuclide Therapy / 2021 / Cilt: 30 - Sayı: 3

A Case with 68Ga-FAPI Positive and 18F-FDG Negative Breast Cancer

68Ga-FAPI Pozitif, 18F-FDG Negatif Meme Kanseri Olgusu

Canan CAN
Halil KOMEK
Cihan GÜNDOĞAN
Hülya ETEM
Pages
201–204
Publication Date
2022-09-03
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This presumes that 68Ga-FAPI PET/CT imaging is superior to 18F-FDG imaging in detecting the primary tumor in breast cancer, thereby suggesting the replacement of FAPI by 18F-FDG in breastcancer staging in the future

📌 3 Key Takeaways

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Objective & Hypothesis:A female patient diagnosed of infiltrative breast carcinoma using tru-cut biopsy underwent 18flourine-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) for staging.
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Key Findings & Data:The tumor was located in the superior external quadrant of the right breast, and did not exhibit pathological uptake in 18F-FDG PET/CT.
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Conclusion & Impact:This presumes that 68Ga-FAPI PET/CT imaging is superior to 18F-FDG imaging in detecting the primary tumor in breast cancer, thereby suggesting the replacement of FAPI by 18F-FDG in breastcancer staging in the future
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

A female patient diagnosed of infiltrative breast carcinoma using tru-cut biopsy underwent 18flourine-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) for staging. The tumor was located in the superior external quadrant of the right breast, and did not exhibit pathological uptake in 18F-FDG PET/CT. Later, gallium-68 (68Ga) fibroblast activation protein-specific inhibitor (FAPI)-04 PET/ CT imaging was performed and the primary tumor showed intense radiotracer accumulation. This presumes that 68Ga-FAPI PET/CT imaging is superior to 18F-FDG imaging in detecting the primary tumor in breast cancer, thereby suggesting the replacement of FAPI by 18F-FDG in breastcancer staging in the future

Özet

Tru-cut biyopsi sonucu infiltratif meme karsinomu gelen bir kadın hastaya evreleme amacıyla 18fluoride-florodeoksiglikoz (18F-FDG) pozitron emisyon tomografi/bilgisayarlı tomografi (PET/BT) görüntüleme yapıldı. Sağ meme üst dış kadranda yer alan tümör, 18F-FDG PET/BT’de patolojik aktivite tutulumu göstermedi. Daha sonra hastaya galyum-68 (68Ga)-fibroblast aktivasyon protein spesifik inhibitör (FAPI)-04 PET/BT görüntüleme yapıldı ve primer tümör yoğun radyofarmasötik tutulumu gösterdi. Bu olgu 68Ga-FAPI PET/BT görüntülemenin meme kanserinde primer tümörleri tespit etmede 18F-FDG görüntülemeden üstün olabileceğini göstermiştir ve gelecekte meme kanseri evrelemesinde 18F-FDG’nin yerini FAPI’nın alabileceğini düşündürmektedir.

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Cite This Article

CAN, C., KOMEK, H., GÜNDOĞAN, C., ETEM, H. (2022). A Case with 68Ga-FAPI Positive and 18F-FDG Negative Breast Cancer. Molecular Imaging and Radionuclide Therapy, Cilt: 30 - Sayı: 3, 201–204. https://ajindex.com/articles/425717

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References (6)

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