Journals / Molecular Imaging and Radionuclide Therapy / 2022 / Cilt: 31 - Sayı: 2

Unusual Uptake of [131 I] in a Tenosynovial Giant Cell Tumour Relapse in a Patient with Differentiated Thyroid Cancer

Diferansiye Tiroid Kanserli Bir Hastada Tenosinovyal Dev Hücreli Tümör Nüksünde Olağandışı [131 I] Tutulumu

Pages
145–147
Publication Date
2022-09-03
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

As far as we know, this report is the first in the literature to a TGCT visualized on post-therapy radioiodine scan.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:A 77-year-old woman with follicular thyroid cancer underwent total thyroidectomy and subsequent Iodine-131 remnant ablation.
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Key Findings & Data:She had a history of a wide tenosynovial giant cell tumor (TGCT) of the right wrist and hand that had been resected thirteen years ago.
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Conclusion & Impact:As far as we know, this report is the first in the literature to a TGCT visualized on post-therapy radioiodine scan.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

A 77-year-old woman with follicular thyroid cancer underwent total thyroidectomy and subsequent Iodine-131 remnant ablation. She had a history of a wide tenosynovial giant cell tumor (TGCT) of the right wrist and hand that had been resected thirteen years ago. Post-therapeutic scintigraphy and single photon emission computed tomography showed mild uptake on the distal right forearm, wrist and hand. Magnetic resonance imaging and posterior histopathology confirmed a relapse of TGCT. No radioiodine adverse effects were reported after a one-year follow-up. As far as we know, this report is the first in the literature to a TGCT visualized on post-therapy radioiodine scan.

Özet

Foliküler tiroid kanserli 77 yaşında bir kadına total tiroidektomi ve ardından İyot-131 remnant ablasyonu uygulandı. On üç yıl önce rezeke edilmiş sağ el bileği ve elde geniş tenosinovyal dev hücreli tümör (TGCT) öyküsü vardı. Tedavi sonrası sintigrafi ve tek foton emisyon tomografisi distal sağ önkol, el bileği ve elde hafif tutulum gösterdi. manyetik rezonans görüntüleme ve posterior histopatoloji, TGCT’nin relapsını doğruladı. Bir yıllık takipten sonra hiçbir radyoiyodin yan etkisi bildirilmemiştir. Bildiğimiz kadarıyla bu rapor, tedavi sonrası radyoiyot taramasında görüntülenen bir TGCT’nin literatürdeki ilk raporudur.

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Cite This Article

Sánchez, F. M. C., Robles, L. G. R., Chollet, X. L. B., Losada, M. M., Garrastachu, P., Villegas, A. C., Lasanta, R. R., Bolton, R. D. (2022). Unusual Uptake of [131 I] in a Tenosynovial Giant Cell Tumour Relapse in a Patient with Differentiated Thyroid Cancer. Molecular Imaging and Radionuclide Therapy, Cilt: 31 - Sayı: 2, 145–147. https://ajindex.com/articles/425709

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References (8)

  1. Gouin F, Noailles T. Localized and diffuse forms of tenosynovial giant cell tumor (formerly giant cell tumor of the tendon sheath and pigmented villonodular synovitis). Orthop Traumatol Surg Res 2017;103:S91-S97
  2. Mastboom MJL, Verspoor FGM, Hanff DF, Gademan MGJ, Dijkstra PDS, Schreuder HWB, Bloem JL, van der Wal RJP, van de Sande MAJ. Severity classification of tenosynovial giant cell tumours on MR imaging. Surg Oncol 2018;27:544-550
  3. Jain JK, Vidyasagar JV, Sagar R, Patel H, Chetan ML, Bajaj A. Arthroscopic synovectomy in pigmented villonodular synovitis of the knee: clinical series and outcome. Int Orthop 2013;37:2363-2369
  4. Mastboom MJL, Palmerini E, Verspoor FGM, Rueten-Budde AJ, Stacchiotti S, Staals EL, Schaap GR, Jutte PC, Aston W, Gelderblom H, Leithner A, Dammerer D, Takeuchi A, Thio Q, Niu X, Wunder JS; TGCT Study Group, van de Sande MAJ. Surgical outcomes of patients with diffuse-type tenosynovial giant-cell tumours: an international, retrospective, cohort study. Lancet Oncol 2019;20:877-886
  5. Liu Z, Xing M. Induction of sodium/iodide symporter (NIS) expression and radioiodine uptake in non-thyroid cancer cells. PLoS One 2012;7:e31729
  6. Oh JR, Ahn BC. False-positive uptake on radioiodine whole-body scintigraphy: physiologic and pathologic variants unrelated to thyroid cancer. Am J Nucl Med Mol Imaging 2012;2:362-385
  7. Anh BC. Physiologic and false positive pathologic uptakes on radioiodine whole body scan. 12 Chapters on Nuclear Medicine. InTech; 2011
  8. Bassetti E, Candreva R, Santucci E. Giant cell tumor of the flexor tendon of the wrist: US and MRI evaluation. Case report. J Ultrasound 2011;14:37-3