SavedAdd your journal

Journals / Molecular Imaging and Radionuclide Therapy / 2022 / Cilt: 31 - Sayı: 1

Myocardial Ischemia on MPI SPECT in a Patient with Acute Myeloid Leukemia Without Significant Coronary Artery Disease

Ciddi Koroner Arter Hastalığı Olmayan Akut Miyeloid Lösemili Bir Hastada MPI SPECT’de Miyokard İskemisi

Chrissa Sioka
Aris Bechlioulis
Evangelos Ntais
Andreas Fotopoulos
Sotirios Giannopoulos
Eleni Kapsali
Christos Katsouras
Pages
63–65
Publication Date
2022-09-03
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Although the etiology is not entirely clear, this case suggested that myocardial perfusion imaging should be considered in patients with AML who received idarubicin to screen for possible myocardial dysfunction.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Herein, we report the case of a 56-year-old male patient with acute myeloid leukemia (AML) in remission who had asymptomatic myocardial ischemia on myocardial perfusion imaging and transthoracic echocardiography.
📊
Key Findings & Data:Angiography did not reveal any significant coronary artery disease.
💡
Conclusion & Impact:Although the etiology is not entirely clear, this case suggested that myocardial perfusion imaging should be considered in patients with AML who received idarubicin to screen for possible myocardial dysfunction.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Herein, we report the case of a 56-year-old male patient with acute myeloid leukemia (AML) in remission who had asymptomatic myocardial ischemia on myocardial perfusion imaging and transthoracic echocardiography. Angiography did not reveal any significant coronary artery disease. Although the etiology is not entirely clear, this case suggested that myocardial perfusion imaging should be considered in patients with AML who received idarubicin to screen for possible myocardial dysfunction.

Özet

Bu çalışmada, miyokard perfüzyon görüntüleme ve transtorasik ekokardiyografide asemptomatik miyokard iskemisi saptanan, remisyondaki akut miyeloid lösemili (AML) 56 yaşında bir erkek hastayı sunuyoruz. Anjiyografide ciddi bir koroner arter hastalığı saptanmadı. Etiyolojisi tam olarak net olmamakla birlikte, bu olgu, olası miyokardiyal disfonksiyon taraması için idarubisin alan AML hastalarında miyokard perfüzyon görüntülemesinin düşünülmesi gerektiğini ortaya koymuştur.

🔖

Cite This Article

Sioka, C., Bechlioulis, A., Ntais, E., Fotopoulos, A., Giannopoulos, S., Kapsali, E., Katsouras, C. (2022). Myocardial Ischemia on MPI SPECT in a Patient with Acute Myeloid Leukemia Without Significant Coronary Artery Disease. Molecular Imaging and Radionuclide Therapy, Cilt: 31 - Sayı: 1, 63–65. https://ajindex.com/articles/425701

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (8)

  1. Sioka C, Exarchopoulos T, Tasiou I, Tzima E, Fotou N, Capizzello A, Ragos V, Tsekeris P, Fotopoulos A. Myocardial perfusion imaging with (99 m)Tc- tetrofosmin SPECT in breast cancer patients that received postoperative radiotherapy: a case-control study. Radiat Oncol 2011;6:151
  2. Giannopoulos S, Markoula S, Sioka C, Zouroudi S, Spiliotopoulou M, Naka KK, Michalis LK, Fotopoulos A, Kyritsis AP. Detecting myocardial ischemia with 99mtechnetium-tetrofosmin myocardial perfusion imaging in ischemic stroke. Neurohospitalist 2017;7:164-168
  3. Roberts WC, Bodey GP, Wertlake PT. The heart in acute leukemia. A study of 420 autopsy cases. Am J Cardiol 1968;21:388-412
  4. Sioka C, Papadimitropoulos K, Michalis L, Pappas K, Lakkas L, Fotopoulos A, Dounousi E. Myocardial ischemia with normal coronary angiography in a chronic kidney disease patient. Cardiol J 2019;26:620-621
  5. Kotsalou I, Georgoulias P, Karydas I, Fourlis S, Sioka C, Zoumboulidis A, Demakopoulos N. A rare case of myocardial infarction and ischemia in a cannabis-addicted patient. Clin Nucl Med 2007;32:130-131
  6. Cohen Y, Amir G, Da’as N, Gillis S, Rund D, Polliack A. Acute myocardial infarction as the presenting symptom of acute myeloblastic leukemia with extreme hyperleukocytosis. Am J Hematol 2002;71:47-49
  7. Khan AA, Ashraf A, Singh R, Rahim A, Rostom W, Hussain M, Renner I, Collins NJ. Incidence, time of occurrence and response to heart failure therapy in patients with anthracycline cardiotoxicity. Intern Med J 2017;47:104-109
  8. Prenner SB, Franken AA, Murphy IG, Mikati IA. Rapid reversal of focal left ventricular hypertrophy and systolic dysfunction resulting from myocardial infiltration by acute lymphoblastic leukemia. Circulation 2016;133:678-679