Journals / Türk Göğüs Kalp Damar Cerrahisi Dergisi / 2020 / Cilt: 28 - Sayı: 3

Latent class analysis for exploring distribution patterns of primary superficial venous insufficiency

Primer yüzeyel venöz yetmezliğin dağılım paternlerinin belirlenmesinde gizli sınıf analizi

Pages
474–479
Publication Date
2022-09-02
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There was no age- or sex-specificdifferences in the chronic venous disease distribution patterns.Conclusion: The latent class analysis, by identifying previouslyunseen subgroups within the sampled population, provides a newapproach to classification of reflux patterns in chronic venous disease.Identification of latent classes may provide understanding of differentpathophysiological bases of venous reflux and more optimal planningfor interventions.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background: This study aims to identify specific segmental distributionpatterns of lower extremity chronic venous disease based on latent classanalysis of Doppler mapping results.Methods: A total of 1,871 lower extremities of 1,218 treatment-naïvepatients (536 males, 682 females; mean age 45.4 years; range, 21 to 87 years)with chronic venous disease referred for Doppler examination betweenSeptember 2009 and August 2018 were included.
📊
Key Findings & Data:Refluxing superficialvenous segments of the lower extremities were mapped and recorded indatabase in 10 distinct anatomic locations as follows: saphenofemoraljunction and proximal greater saphenous vein, mid and distal thighgreater saphenous vein, anterior and posterior accessory saphenous veins,proximal and distal calf greater saphenous vein, saphenopopliteal junctionand proximal lesser saphenous vein, distal lesser saphenous vein, andintersaphenous veins including Giacomini’s vein.
💡
Conclusion & Impact:There was no age- or sex-specificdifferences in the chronic venous disease distribution patterns.Conclusion: The latent class analysis, by identifying previouslyunseen subgroups within the sampled population, provides a newapproach to classification of reflux patterns in chronic venous disease.Identification of latent classes may provide understanding of differentpathophysiological bases of venous reflux and more optimal planningfor interventions.
🔬Design:Modeling & Simulation
📍Scope:2009 Verileri
⚙️Variables:Domain Parameters

Abstract

Background: This study aims to identify specific segmental distributionpatterns of lower extremity chronic venous disease based on latent classanalysis of Doppler mapping results.Methods: A total of 1,871 lower extremities of 1,218 treatment-naïvepatients (536 males, 682 females; mean age 45.4 years; range, 21 to 87 years)with chronic venous disease referred for Doppler examination betweenSeptember 2009 and August 2018 were included. Refluxing superficialvenous segments of the lower extremities were mapped and recorded indatabase in 10 distinct anatomic locations as follows: saphenofemoraljunction and proximal greater saphenous vein, mid and distal thighgreater saphenous vein, anterior and posterior accessory saphenous veins,proximal and distal calf greater saphenous vein, saphenopopliteal junctionand proximal lesser saphenous vein, distal lesser saphenous vein, andintersaphenous veins including Giacomini’s vein. Repeated examinationswere excluded. The latent class analysis was applied to identify anypossible anatomic distribution patterns of chronic venous disease.Results: Bayesian information criteria revealed three latent class modelsfit for refluxing segment distribution as follows: 58.2% (n=1,089)were above-the-knee greater saphenous vein segments includingsaphenofemoral junction (pattern 1); 29.3% (n=548) were below-theknee greater saphenous vein segments (pattern 2); and 12.5% (n=234)were lesser saphenous vein segments and intersaphenous veins includingGiacomini’s vein (pattern 3). There was no age- or sex-specificdifferences in the chronic venous disease distribution patterns.Conclusion: The latent class analysis, by identifying previouslyunseen subgroups within the sampled population, provides a newapproach to classification of reflux patterns in chronic venous disease.Identification of latent classes may provide understanding of differentpathophysiological bases of venous reflux and more optimal planningfor interventions.

Özet

Amaç: Bu çalışmada Doppler haritalama sonuçlarına göre gizli sınıf analizine dayanarak, alt ekstremitenin kronik venöz hastalığının spesifik segmental dağılım paternleri belirlendi. Ça­lış­ma pla­nı: Çalışmaya Eylül 2009 - Ağustos 2018 tarihleri arasında Doppler incelemesi için yönlendirilen daha önce tedavi edilmemiş, kronik venöz hastalığı olan 1,218 hastanın (536 erkek, 682 kadın; ort. yaş 45.4 yıl; dağılım, 21-87 yıl) toplam 1,871 alt ekstremitesi alındı. Alt ekstremitenin geri akışlı yüzeyel ven segmentleri 10 farklı anatomik lokasyonda haritalandı ve veri tabanına kaydedildi: safenofemoral kavşak ve proksimal büyük safen ven, orta ve distal kalça büyük safen ven, ön ve arka aksesuar safen venler, proksimal ve distal kalf büyük safen ven, safenopopliteal kavşak ve proksimal büyük safen ven, distal küçük safen ven ve Giacomini veni dahil olmak üzere intersafen venler. Tekrarlı incelemeler hariç tutuldu. Kronik venöz hastalığının muhtemel anatomik dağılım paternlerini belirlemek için gizli sınıf analizi uygulandı. Bulgular: Bayes bilgi kriterleri, geri akışlı segment dağılımına uyan üç gizli sınıf modeli ortaya çıkardı: %58.2’si (n=1089) safenofemoral kavşak dahil diz üstü büyük safen ven segmentleri (patern 1); %29.3’ü (n=548) diz altı büyük safen ven segmentleri (patern 2) ve %12.5’i (n=234) küçük safen ven segmentleri ve Giacomini veni dahil olmak üzere intersafen venler (patern 3). Kronik venöz hastalık dağılım paternleri arasında yaş veya cinsiyete özgü farklılıklar izlenmedi. So­nuç: Gizli sınıf analizi, çalışılan popülasyon içerisinde daha önce görülmemiş alt grupları belirleyerek, kronik venöz hastalığın geri akış paternlerinin sınıflandırılmasında yeni bir yaklaşım sunmaktadır. Gizli sınıfların belirlenmesi, venöz geri akışın farkı patofizyolojik temellerinin anlaşılmasını ve girişimler için daha uygun planlama yapılmasını sağlayabilir.

🔖

Cite This Article

TÜRELİ, D., BALTACIOĞLU, N. A. (2022). Latent class analysis for exploring distribution patterns of primary superficial venous insufficiency. Türk Göğüs Kalp Damar Cerrahisi Dergisi, Cilt: 28 - Sayı: 3, 474–479. https://ajindex.com/articles/423619

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Wittens C, Davies AH, Bækgaard N, Broholm R, Cavezzi A, Chastanet S, et al. Editor's Choice - Management of Chronic Venous Disease: Clinical Practice Guidelines of the European Society for Vascular Surgery (ESVS). Eur J Vasc Endovasc Surg 2015;49:678-737
  2. García-Gimeno M, Rodríguez-Camarero S, Tagarro-Villalba S, Ramalle-Gomara E, González-González E, Arranz MA, et al. Duplex mapping of 2036 primary varicose veins. J Vasc Surg 2009;49:681-9
  3. Lee AJ, Robertson LA, Boghossian SM, Allan PL, Ruckley CV, Fowkes FG, et al. Progression of varicose veins and chronic venous insufficiency in the general population in the Edinburgh Vein Study. J Vasc Surg Venous Lymphat Disord 2015;3:18-26
  4. Labropoulos N, Giannoukas AD, Delis K, Mansour MA, Kang SS, Nicolaides AN, et al. Where does venous reflux start? J Vasc Surg 1997;26:736-42
  5. Bernardini E, De Rango P, Piccioli R, Bisacci C, Pagliuca V, Genovese G, et al. Development of primary superficial venous insufficiency: the ascending theory. Observational and hemodynamic data from a 9-year experience. Ann Vasc Surg 2010;24:709-20
  6. Cooper DG, Hillman-Cooper CS, Barker SG, Hollingsworth SJ. Primary varicose veins: the sapheno-femoral junction, distribution of varicosities and patterns of incompetence. Eur J Vasc Endovasc Surg 2003;25:53-9
  7. Engelhorn CA, Manetti R, Baviera MM, Bombonato GM, Lonardoni M, Cassou MF, et al. Progression of reflux patterns in saphenous veins of women with chronic venous valvular insufficiency. Phlebology 2012;27:25-32
  8. Linzer DA, Lewis JB. poLCA: An R Package for Polytomous Variable Latent Class Analysis. Journal of Statistical Software 2011;42:1-29
  9. Rindskopf D, Rindskopf W. The value of latent class analysis in medical diagnosis. Stat Med 1986;5:21-7
  10. Vermunt JK, Magidson J. Latent class cluster analysis. In: Hagenaars JA, McCutcheon AL, editors. Applied latent class analysis. New York: Cambridge University Press; 2002. p. 89-106
  11. Kachlik D, Pechacek V, Baca V, Musil V. The superficial venous system of the lower extremity: new nomenclature. Phlebology 2010;25:113-23
  12. Lanza ST, Rhoades BL. Latent class analysis: an alternative perspective on subgroup analysis in prevention and treatment. Prev Sci 2013;14:157-68
  13. Forster MR. Key Concepts in Model Selection: Performance and Generalizability. J Math Psychol 2000;44:205-31. 14. van den Bergh M, van Kollenburg GH, Vermunt JK. Deciding on the Starting Number of Classes of a Latent Class Tree. Sociol Methodol 2