SavedAdd your journal

Journals / Marmara Medical Journal / 2026 / Volume: 31 Issue: 1

A very rare case of cervicothoracic vertebral synostosis spanning eight adjacent segments: congenital vs acquired

Sekiz ardışık segmenti kapsayan çok nadir bir servikotorakal vertebral sinostoz olgusu: konjenital mi, edinsel mi?

İsmet Cengiç
Derya Türeli
Hilal Altaş
Onur Buğdaycı
Pages
—
Publication Date
2018-02-26
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Block vertebrae spanning several levels have previously been reported; but, this is the first report of an acquired cervicothoracic fusion spanning 8 adjacent vertebral bodies.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Cervical roentgenogram revealed a long-segment cervicothoracic vertebral fusion spanning 8 adjacent spinal levels.
📊
Key Findings & Data:The patient was evaluated with computed tomography (CT) and magnetic resonance (MR) imagings of the spine, electromyography (EMG) and growth differentiation factor 6 (GDF6) gene mutation analysis.
💡
Conclusion & Impact:Block vertebrae spanning several levels have previously been reported; but, this is the first report of an acquired cervicothoracic fusion spanning 8 adjacent vertebral bodies.
🔬Design:Case Report
📍Scope:Comprehensive Sample
⚙️Variables:Cervicothoracic vertebral synostosis · Klippel – Feil syndrome · Magnetic resonance imaging

Abstract

Cervical roentgenogram revealed a long-segment cervicothoracic vertebral fusion spanning 8 adjacent spinal levels. The patient was evaluated with computed tomography (CT) and magnetic resonance (MR) imagings of the spine, electromyography (EMG) and growth differentiation factor 6 (GDF6) gene mutation analysis. Imaging findings were atypical for congenital block vertebrae and there was no GDF6 mutation. A revision of very old medical records and patient’s recollections revealed long-term stay in sanatorium for rehabilitation of chronic partially-treated brucella spondylodiscitis during adolescence. Block vertebrae spanning several levels have previously been reported; but, this is the first report of an acquired cervicothoracic fusion spanning 8 adjacent vertebral bodies.

Özet

Yaşlı bir kadın hasta travma sonrası akut boyun ağrısı ile başvurdu. Servikal direkt grafisinde 8 ardışık spinal seviyeyi kapsayan uzun segment servikotorakal vertebral füzyon saptandı. Hasta spinal bilgisayarlı tomografi (BT) ve magnetik rezonans (MR) görüntüleme, elektromiyografi (EMG), ve büyüme-farklılaşma faktörü 6 [Growth differentiation factor 6 (GDF6)] gen mutasyonu analizi ile detaylı tetkik edildi. Görüntüleme bulguları konjenital blok vertebra için atipik olan olguda GDF6 gen mutasyonu saptanmadı. Hastanın eski tıbbi raporları ve anamnezinde adolesan dönemde kronik ve kısmen tedavi edilmiş brucella spondilodiskiti rehabilitasyonu amacıyla sanatoryumda uzun dönemli yatış mevcut idi. Birkaç seviyeyi kapsayan blok vertebra olguları daha önceden bildirilmiş olmakla birlikte; bu, 8 ardışık vertebral cismi kapsayan ilk edinsel servikotorakal füzyon olgusudur.

🔖

Cite This Article

Cengiç, İ., Türeli, D., Altaş, H., Buğdaycı, O. (2018). A very rare case of cervicothoracic vertebral synostosis spanning eight adjacent segments: congenital vs acquired. Marmara Medical Journal, Volume: 31 Issue: 1. https://doi.org/10.5472/marumj.398944

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (8)

  1. Thawait GK, Chhabra A, Carrino JA. Spine segmentation and enumeration and normal variants. Radiol Clin North Am 2012;50:587-98. doi: 10.1016/j.rcl.2012.04.003
  2. Kumar R, Guinto FC, Jr, Madewell JE, Swischuk LE, David R. The vertebral body: radiographic configurations in various congenital and acquired disorders. Radiographics 1988;8:455-85. doi:10.1148/radiographics.8.3.3380991
  3. Klimo P Jr, Rao G, Brockmeyer D. Congenital anomalies of the cervical spine. Neurosurg Clin N Am 2007;18:463-78. doi:10.1016/j.nec.2007.04.005
  4. Nguyen VD, Tyrrel R. Klippel-Feil syndrome: patterns of bony fusion and wasp-waist sign. Skeletal Radiol 1993;22:519-23.
  5. Guille JT, Sherk HH. Congenital osseous anomalies of the upper and lower cervical spine in children. J Bone Joint Surg Am 2002;84-A:277-88.
  6. Yuksel M, Karabiber H, Yuksel KZ, Parmaksiz G. Diagnostic importance of 3D CT images in Klippel-Feil Syndrome with multiple skeletal anomalies: a case report. Korean J Radiol 2005;6:278-81. doi:10.3348/kjr.2005.6.4.278
  7. McBride WZ. Klippel-Feil syndrome.Am Fam Physician 1992;45:633-5.
  8. Theiss SM, Smith MD, Winter RB. The long-term follow-up of patients with Klippel-Feil syndrome and congenital scoliosis. Spine (Phila Pa 1976). 1997;22:1219-22.