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Journals / Marmara Medical Journal / 2026 / Volume: 39 Issue: 2

Pancreatic squamous cell carcinoma – A rare presentation of neoplasia

Vitorino Modesto Dos Santos(Catholic University (UCB) and Armed Forces Hospital (HFA))0000-0002-7033-6074
Mariana Melo(Public Workers State Hospital Francisco Morato de Oliveira)0000-0003-4064-8787
Lister Santos(Public Workers State Hospital Francisco Morato de Oliveira)0000-0003-4647-4044
Camila Silva(Public Workers State Hospital Francisco Morato de Oliveira)0009-0001-8998-6800
Bruna Pignataro(Public Workers State Hospital Francisco Morato de Oliveira)0009-0003-9517-4475
Andressa Tedeschi(University of Americas)0009-0008-4378-4120
Pages
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Publication Date
2026-05-21
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The rarity of this neoplasm impacts its management, highlighting the need for more research to improve diagnosis and treatment and, consequently, the prognosis of patients.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Pancreatic cancer (PC) has high morbidity and mortality rates, with a five-year survival rate of less than 10%.
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Key Findings & Data:Within this spectrum, squamous cell carcinoma (SCC) of the pancreas stands out as a rare and aggressive form, representing between 0.5% and 2% of diagnosed cases.
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Conclusion & Impact:The rarity of this neoplasm impacts its management, highlighting the need for more research to improve diagnosis and treatment and, consequently, the prognosis of patients.
🔬Design:Case Report
📍Scope:Comprehensive Sample
⚙️Variables:Carcinoma · Neoplasia · Oncology

Abstract

Pancreatic cancer (PC) has high morbidity and mortality rates, with a five-year survival rate of less than 10%. Within this spectrum, squamous cell carcinoma (SCC) of the pancreas stands out as a rare and aggressive form, representing between 0.5% and 2% of diagnosed cases. This report describes the case of a patient in whom a lesion in the body of the pancreas was incidentally identified, and he underwent a body and tail pancreatectomy. The diagnosis of pancreatic SCC was confirmed through anatomopathological examination, adjuvant treatment with the FOLFIRINOX regimen was carried out and, after eight months of outpatient follow-up, there was no evidence of recurrence or progression of the disease. The rarity of this neoplasm impacts its management, highlighting the need for more research to improve diagnosis and treatment and, consequently, the prognosis of patients.

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Cite This Article

Santos, V. M. D., Melo, M., Santos, L., Silva, C., Pignataro, B., Tedeschi, A., *, V. M. D. S. (2026). Pancreatic squamous cell carcinoma – A rare presentation of neoplasia. Marmara Medical Journal, Volume: 39 Issue: 2. https://doi.org/10.5472/marumj.1955630

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