SavedAdd your journal

Journals / Düzce Tıp Fakültesi Dergisi / 2007 / Cilt: 9 - Sayı: 3

Regression Of Pseudo Hypophysial Mass By Medical Therapy In A Patient With Hypothyroidism And Galactore

Hipotiroidizm Ve Galaktoreli Bir Olguda Yalanci Hipofiz Kitlesinin Medikal Tedavi Ile Regresyonu

Alptekin TOSUN
Salih TOSUN²
Pages
44–47
Publication Date
2007-12-01
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion, on patients with primary hypothyroidism and hyperprolactinemia although hypophysial gland dimensions increased, hormone theraphy have to applied primary before surgery or bromocryptine therapy and pursued by clinical, laboratory and radiological.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:amenhorrea and galactorea had investigated.
📊
Key Findings & Data:Prolactin and TSH levels were increased in our patient.
💡
Conclusion & Impact:In conclusion, on patients with primary hypothyroidism and hyperprolactinemia although hypophysial gland dimensions increased, hormone theraphy have to applied primary before surgery or bromocryptine therapy and pursued by clinical, laboratory and radiological.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Hipotiroidizm · hiperprolaktinemi · galaktore

Abstract

amenhorrea and galactorea had investigated. Prolactin and TSH levels were increased in our patient. Ultrasonographic examination revealed thyroiditis. CT examination revealed expansion on superior contour of gland and MRI showed increased size and contrast material fixation. After medical treatment hormone levels and gland signal intensity on MRI back to normal. Hypothyroidism secondary thyroiditis resulted cell hyperplasia and showed pseudoadenoma on radiological examination. In conclusion, on patients with primary hypothyroidism and hyperprolactinemia although hypophysial gland dimensions increased, hormone theraphy have to applied primary before surgery or bromocryptine therapy and pursued by clinical, laboratory and radiological. Therefore medical treatment have considered in this disease

Özet

Hiperprolaktinemi, hipotiroidizm hastalarinda görülebilmektedir. 24 yasinda bayan hasta amenore ve galaktore sikayetleri nedeniyle incelemeye alindi. Hastamizda prolaktin ve TSH degerlerinde artis mevcuttu. Ultrasonografik tetkikteyse tiroiditle uyumlu bulgular izlendi. Bilgisayarli tomografide gland üst konturunda ekspansiyon ve manyetik rezonans görüntülemede (MRG) hipofiz gland boyut ve kontrast fiksasyonunda artis mevcuttu. Medikal tedavi sonrasinda hormon degerlerinde ve MRG’d e gland sinyal intensitesinde normale dönüs saptandi. Geçirilmis tiroidite sekonder gelisen hipotiroidizm hipofizde hücre hiperplazisine neden olarak radyolojik incelemede yalanci adenom izlenimi verebilmektedir. Sonuç olarak primer hipotiroidizm ve hiperprolaktinemili olgularinda hipofiz gland boyutlarinda difüz artis mevcut ise cerrahi veya bromokriptin tedavisi öncesinde tiroid hormon replasmani tedavide ilk basamak olarak uygulanmali ve klinik, laboratuar ve radyolojik olarak takip edilmelidir. Dolayisiyla medikal tedavi bu tip hastalarda yeterli olabildigi göz önünde tutulmalidir

🔖

Cite This Article

TOSUN, A., TOSUN², S. (2007). Regression Of Pseudo Hypophysial Mass By Medical Therapy In A Patient With Hypothyroidism And Galactore. Düzce Tıp Fakültesi Dergisi, Cilt: 9 - Sayı: 3, 44–47. https://ajindex.com/articles/420302

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (8)

  1. Shimono T, Hatabu H, Kasagi K, Miki Y Nishizawa S, Misaki T, et al. Rapid progression of pituitary hyperplasia in humans with primary hypothyroidism: demonstration with MR imaging. Radiology 213:383-8, 1999.
  2. Veldman RG, Berg G, Pincus SM, Frolich M, Veldhuis JD, Roelfsema RG. Increased episodic release and disorderliness of prolactin secretion in both micro- and macroprolactinomas. Eur J Endocrinol 140:192-200, 1999.
  3. Ozbey N, Sariyildiz E, Yilmaz E, OrhanY Sencer E, Molvalilar S. Primary hypothyroidism with hyperprolactinaemia and pituitary enlargement mimicking a pituitary macroadenoma. Int J Clin Pract 51:409-11, 1999.
  4. Armstrong MR, Douek M, Schellinger D Patronas NJ. Regression of pituitary macroadenoma after pituitary apoplexy: CT and MR studies. Comput Assit Tomog 15:832-4, 1991.
  5. Joshi AS, Woolf PD. Pituitary hyperplasia secondary to primary hypothyroidism: A case report and review of the literature. Pituitary 8:99-103, 2005.
  6. Wolansky LJ, Leavitt GD, Elias BJ, Lee HJ Dasmahapatra A, Byme W. MRI of pituitary hyperplasia in hypothyroidism. Neuroradiology 38:50-2, 1996.
  7. Ashley WW, Ojemann JG, Park TS Wippold FJ. Primary hypothyroidism in a 12-year-old girl with a suprasellar pituitary mass: rapid regression after thyroid replacement theraphy: case report. J Neurosurg 102:413-6, 2005.
  8. Khawaja NM, Taher BM, Barham ME Naser AA, Hadidy AM, Ahmad AT, et al. Pituitary enlargement in patients with primary hypothyroidism. Endocr Pract 12:29-34, 2006.