Journals / GORM:Gynecology Obstetrics & Reproductive Medicine / 2014 / Cilt: 20 - Sayı: 3

Obstetrik Doppler parametlerinin yenidoğanda oksidatif stres ve Kord pH’sını öngörmedeki değeri

Predictive value of obstetrical doppler parameters to predict oxidative stress and cord blood PH in newborn infants

Pages
126–130
DOI
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CONCLUSION: This data led us to conclude that UmA Doppler parameters at early periods of active labor in high-risk population may be predictive for newborn well-being.

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: We sought to determine the clinical value of obstetrical Doppler performed at early stages of active labor in predicting oxidative stress and cord blood pH in neonates.
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Key Findings & Data:STUDY DESIGN: A total of 54 pregnant women with oligohydramnios who were in active labor were en- rolled for the study.
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Conclusion & Impact:CONCLUSION: This data led us to conclude that UmA Doppler parameters at early periods of active labor in high-risk population may be predictive for newborn well-being.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: We sought to determine the clinical value of obstetrical Doppler performed at early stages of active labor in predicting oxidative stress and cord blood pH in neonates. STUDY DESIGN: A total of 54 pregnant women with oligohydramnios who were in active labor were en- rolled for the study. Active labor was confirmed for each woman according to uterine contraction fre- quency, cervical dilatation and effacement. Subjects with amniotic fluid index (AFI) lower than 80 mm were included in the study. Doppler assessment included uterine artery (UtA), umbilical artery (UmA) and middle cerebral artery (MCA) measurements. Umbilical cord lengths were measured after delivery. Cord blood gamma glutamyl transferase (GGT) levels and umbilical arterial blood pH were analyzed. RESULTS: Umbilical artery PI significantly predicted cord blood GGT levels >101 ıu/L (area under curve=0.690, P=0.018). Umbilical artery PI significantly predicted cord blood pH<7.21 (area under curve (AUC) =0.870, P=0.015). None of the MCA Doppler parameters were significantly correlated with cord blood pH or cord blood GGT (P>0.05). Also, MCA Doppler studies could not significantly predict cord blood pH<7.21 OR GGT>101(P>0.05). CONCLUSION: This data led us to conclude that UmA Doppler parameters at early periods of active labor in high-risk population may be predictive for newborn well-being.

Özet

AMAÇ: Aktif doğum eyleminin erken döneminde obsterik Dopplerin oksidatif stres ve yenidoğan kord kanı pH sını öngörmedeki değerini tanımlamayı amaçladık. GEREÇ VE YÖNTEM: Çalışmaya aktif doğum eyleminde oligohidramniozu olan 54 hasta dahil edildi. Aktif doğum eylemi her hasta için uterin kontraksiyon, servikal dilatasyon ve efasman ile doğrulandı. Amniotik sıvı indeksi (AFİ) 80 mm altında olan hastalar dahil edildi. Doppler değerlendirmesi umbilikal arter, uterin arter ve orta serebral arter parametrelerini içermekteydi. Umbilikal kord uzunluğu doğumdan sonra ölçüldü. Kord kanı gama glutamil transferaz (GGT) düzeyi ve umbilikal arter PH düzeyi ölçüldü. BULGULAR: Umbilikal arter PI değeri, kord kanı GGT> 101ıu/L düzeyini anlamlı olarak öngörmekteydi (AUC=0,690, p=0,018). Umbilikal arter PI değeri, kord kanı pH 0,05). Ayrıca MCA Doppler çalımaları kord kanı pH 101 değerini öngörmüyordu (p>0,05). SONUÇ: Bu veriler aktif doğum eyleminin erken dönemindeki yüksek riskli hastalarda umbilikal arter Doppler parametrelerinin yenidoğan iyilik halini değerlendirmede öngörücü olabileceğini göstermektedir.

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Cite This Article

KORKMAZ, V., TOSUN, A., ÖZKAYA, E., MENEKŞE, D. B., KÜÇÜKÖZKAN, T., KARA, F. (2014). Obstetrik Doppler parametlerinin yenidoğanda oksidatif stres ve Kord pH’sını öngörmedeki değeri. GORM:Gynecology Obstetrics & Reproductive Medicine, Cilt: 20 - Sayı: 3, 126–130. https://ajindex.com/articles/199780

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