Journals / Turkish Neurosurgery / 2013 / Cilt: 23 - Sayı: 3

Kafa Travmalarında Difüzyon MR ile Tespit Edilen Hemorajik ve İskemik Lezyonların Serum NT-proBNP Düzeyleri ile Korelasyonu

The Correlation of Serum NT-proBNP Levels of Hemorrhagic and Ischemic Lesions Detected with Diffusion MRI in Head Traumas

Pages
336–343
DOI
—
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⚡ TL;DR(Too Long; Didn't Read)

In addition, the fact that it has been established that the serum NT-proBNP values of patients with increasing cerebral parenchymal lesion dimensions on the advancing hours after the trauma increase suggests that serum NT- proBNP values may be significant in the follow-up of the dimensions of cerebral parenchymal damage.

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Objective & Hypothesis:AIM: To evaluate the correlation between the dimensions of ischemic and hemorrhagic lesions detected by diffusion MRI and the changes in lesion dimensions with serum NT-proBNP levels in mild and moderate head trauma.
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Key Findings & Data:MATERIAL and METHODS: 30 patients were assessed in our study.
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Conclusion & Impact:In addition, the fact that it has been established that the serum NT-proBNP values of patients with increasing cerebral parenchymal lesion dimensions on the advancing hours after the trauma increase suggests that serum NT- proBNP values may be significant in the follow-up of the dimensions of cerebral parenchymal damage.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

AIM: To evaluate the correlation between the dimensions of ischemic and hemorrhagic lesions detected by diffusion MRI and the changes in lesion dimensions with serum NT-proBNP levels in mild and moderate head trauma. MATERIAL and METHODS: 30 patients were assessed in our study. A control group of 10 individuals with no trauma history was formed in order to establish normal serum NT-proBNP values. Patients underwent brain diffusion MRI 24 and 48 hours following admittance. Their plasma NT-proBNP levels were checked at the same stages. results: The correlation between the values of 24th and 48th hour Intra-axial hemorrhage (IAHEM) and Intra-axial ischemia (IAISC) and the values of 24th and 48th hour NT-proBNP was established as statistically significant. CONCLUSION: It was observed that the serum NT-proBNP values could be higher in patients with wide intra-axial lesion following head trauma than patients with smaller intra-axial lesions. In addition, the fact that it has been established that the serum NT-proBNP values of patients with increasing cerebral parenchymal lesion dimensions on the advancing hours after the trauma increase suggests that serum NT- proBNP values may be significant in the follow-up of the dimensions of cerebral parenchymal damage.

Özet

AMAÇ: Hafif ve orta dereceli kafa travmalarında difüzyon MR da tespit edilen iskemik ve hemorajik lezyonların boyutları ve lezyon boyutlarındaki değişimler ile serum NT-proBNP düzeyleri arasındaki ilişkiyi değerlendirmek. YÖNTEM ve GEREÇLER: Çalışmamızda kafa travmalı 30 hasta değerlendirildi. Travma öyküsü olmayan 10 kişilik kontrol grubu normal serum NT-proBNP değerlerini belirlemek için oluşturuldu. Hastalara yatışlarından itibaren 24. saatte ve 48. saatte beyin difüzyon MR çekildi. Aynı dönemlerde plazma NT-proBNP düzeyleri bakıldı. BULGUlAR: 24. ve 48. saat Intraaksiyal hemoraji (IAHEM) ve Intraaksiyal iskemi (IAISC) değerleri ile 24. ve 48. saat NT-proBNP değerleri arasındaki ilişki istatistiksel olarak anlamlı bulundu. sOnuÇ: Serum NT-proBNP değerlerinin kafa travmaları sonrası intraaksiyal lezyonu geniş olan hastalarda daha küçük intraaksiyal lezyonlulardan yüksek olabileceği izlendi. Ayrıca travmanın ilerleyen saatlerinde serebral parankimal lezyon boyutları artan hastalarda serum NT-proBNP değerlerinin de artmasının belirlenmesi, serum NT-proBNP değerlerinin serebral parankimal hasarın boyutlarının takibinde önemli olabileceğini düşündürmektedir.

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Cite This Article

AKGÜN, B., EROL, F. S., YILDIRIM, H., İLHAN, N., KAPLAN, M. (2013). Kafa Travmalarında Difüzyon MR ile Tespit Edilen Hemorajik ve İskemik Lezyonların Serum NT-proBNP Düzeyleri ile Korelasyonu. Turkish Neurosurgery, Cilt: 23 - Sayı: 3, 336–343. https://ajindex.com/articles/417739

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