SavedAdd your journal

Journals / Turkish journal of vascular surgery / 2021 / Cilt: 30 - Sayı: 1

The effect of neutrophil/lymphocyte ratio and tomography measurements at the time of diagnosis in predicting aneurysm rupture in patients with abdominal aortic aneurysms

AYDIN TUNÇAY
DENİZ ELÇİK
Pages
1–6
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Our study results indicate that abdominal aortic diameter, smoking, and hypertension are the risk factors for rupture of AAAs.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objectives: In this study, we aimed to examine the effect of neutrophil/lymphocyte ratio (NLR) in predicting rupture in patients with abdominal aortic aneurysms (AAA).
📊
Key Findings & Data:Patients and methods: Between March 2014 and September 2017, a total of 42 patients (32 males, 6 females; mean age 66±11.7 years; range, 57 to 81 years) with an AAA were retrospectively analyzed.
💡
Conclusion & Impact:Conclusion: Our study results indicate that abdominal aortic diameter, smoking, and hypertension are the risk factors for rupture of AAAs.
🔬Design:Research Article
📍Scope:2014 Verileri
⚙️Variables:Domain Parameters

Özet

Objectives: In this study, we aimed to examine the effect of neutrophil/lymphocyte ratio (NLR) in predicting rupture in patients with abdominal aortic aneurysms (AAA). Patients and methods: Between March 2014 and September 2017, a total of 42 patients (32 males, 6 females; mean age 66±11.7 years; range, 57 to 81 years) with an AAA were retrospectively analyzed. The patients were divided into two groups as the ruptured (n=13) and non-ruptured groups (n=29), and the effects of baseline NLR and computed tomography results on rupture were evaluated. Results: The mean follow-up was 2.5 (range, 2 to 4) years. The mean abdominal aortic size, neutrophil percentage, and NLR were significantly higher in the ruptured group, while the mean lymphocyte ratio was significantly lower in the ruptured group. There was a significant correlation between the abdominal aortic size and NLR. Using the receiver operating characteristics, the NLR was found to be more sensitive and specific than the abdominal aortic diameter in predicting rupture. Conclusion: Our study results indicate that abdominal aortic diameter, smoking, and hypertension are the risk factors for rupture of AAAs. In addition to classical risk factors, NLR is a novel and simple predictor of aortic rupture.

🔖

Cite This Article

TUNÇAY, A., ELÇİK, D. (2021). The effect of neutrophil/lymphocyte ratio and tomography measurements at the time of diagnosis in predicting aneurysm rupture in patients with abdominal aortic aneurysms. Turkish journal of vascular surgery, Cilt: 30 - Sayı: 1, 1–6. https://ajindex.com/articles/417628

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Sonesson B, Länne T, Hansen F, Sandgren T. Infrarenal aortic diameter in the healthy person. Eur J Vasc Surg 1994;8:89-95
  2. Sakalihasan N, Limet R, Defawe OD. Abdominal aortic aneurysm. Lancet 2005;365:1577-89
  3. Thompson RW, Parks WC. Role of matrix metalloproteinases in abdominal aortic aneurysms. Ann N Y Acad Sci 1996;800:157-74
  4. Duftner C, Seiler R, Klein-Weigel P, Göbel H, Goldberger C, Ihling C, et al. High prevalence of circulating CD4+CD28- T-cells in patients with small abdominal aortic aneurysms. Arterioscler Thromb Vasc Biol 2005;25:1347-52
  5. Watanabe T, Shibata M, Nishiyama H, Soeda S, Furukawa S, Gonda K, et al. Serum levels of rapid turnover proteins are decreased and related to systemic inflammation in patients with ovarian cancer. Oncol Lett 2014;7:373-7
  6. Kaya MG. Inflammation and coronary artery disease: as a new biomarker neutrophil/lymphocyte ratio. Turk Kardiyol Dern Ars 2013;41:191-2
  7. Brown LC, Powell JT. Risk factors for aneurysm rupture in patients kept under ultrasound surveillance. UK Small Aneurysm Trial Participants. Ann Surg 1999;230:289-96;
  8. Allaire E, Schneider F, Saucy F, Dai J, Cochennec F, Michineau S, Zidi M, Becquemin JP, Kirsch M, Gervais M. New insight in aetiopathogenesis of aortic diseases. Eur J Vasc Endovasc Surg 2009;37:531-7
  9. Weintraub NL. Understanding abdominal aortic aneurysm. N Engl J Med 2009;361:1114-6
  10. Nordon IM, Hinchliffe RJ, Loftus IM, Thompson MM. Pathophysiology and epidemiology of abdominal aortic aneurysms. Nat Rev Cardiol 2011;8:92-102
  11. Libby P, Ridker PM, Maseri A. Inflammation and atherosclerosis. Circulation 2002;105:1135-43
  12. Zahorec R. Ratio of neutrophil to lymphocyte counts-- rapid and simple parameter of systemic inflammation and stress in critically ill. Bratisl Lek Listy 2001;102:5-14
  13. Stone PH. C-reactive protein to identify early risk for development of calcific aortic stenosis: right marker? Wrong time? J Am Coll Cardiol 2007;50:1999-2001
  14. Avci A, Elnur A, Göksel A, Serdar F, Servet I, Atilla K, et al. The relationship between neutrophil/lymphocyte ratio and calcific aortic stenosis. Echocardiography 2014;31:1031-5
  15. Oksuz F, Elcik D, Yarlioglues M, Duran M, Ozturk S, Celik IE, et al. The relationship between lymphocyte-to-monocyte ratio and saphenous vein graft patency in patients with coronary artery bypass graft. Biomark Med 2017;11:867-76
  16. Bakogiannis C, Sachse M, Stamatelopoulos K, Stellos K. Platelet-derived chemokines in inflammat