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Journals / Kırıkkale Üniversitesi Tıp Fakültesi Dergisi / 2021 / Cilt: 23 - Sayı: 1

Effects of 72-Hour Trimethazidine in Open Heart Surgery on Myocardial Ischemia

AÇIK KALP CERRAHİSİNDE 72 SAATLİK TRİMETAZİDİN UYGULAMASININ MİYOKARD İSKEMİSİ ÜZERİNE ETKİLERİ

Hüseyin GEMALMAZ
Yıldırım GÜLTEKİN
Tuğrul KURAL
Pages
49–58
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Objective: The aim of this study is to show the effects of 72-hour long trimethazidine (TMZ) administration on myocardial ischemia before open heart surgery.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: The aim of this study is to show the effects of 72-hour long trimethazidine (TMZ) administration on myocardial ischemia before open heart surgery.
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Key Findings & Data:Objective: The aim of this study is to show the effects of 72-hour long trimethazidine (TMZ) administration on myocardial ischemia before open heart surgery.
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Conclusion & Impact:Objective: The aim of this study is to show the effects of 72-hour long trimethazidine (TMZ) administration on myocardial ischemia before open heart surgery.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Koroner bypass · trimetazidin · troponin I

Abstract

Objective: The aim of this study is to show the effects of 72-hour long trimethazidine (TMZ) administration on myocardial ischemia before open heart surgery.

Özet

Amaç: Bu çalışmanın amacı açık kalp cerrahisi öncesi 72 saatlik trimetazidin (TMZ) uygulamasının miyokard iskemisi üzerine etkilerini göstermektir.

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Cite This Article

GEMALMAZ, H., GÜLTEKİN, Y., KURAL, T. (2021). Effects of 72-Hour Trimethazidine in Open Heart Surgery on Myocardial Ischemia. Kırıkkale Üniversitesi Tıp Fakültesi Dergisi, Cilt: 23 - Sayı: 1, 49–58. https://ajindex.com/articles/413870

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References (15)

  1. Ascione R, Lloyd CT, Underwood MJ, Lotto AA, Pitsis AA, Angelini GD. Inflammatory response after coronary revascularization with or without cardiopulmonary bypass. Ann Thorac Surg. 2000;69(4):1198–204
  2. Parissis T, Adamopoulos S, Farmakis D, Flippatos G, Paraskevaidis I, Kremastinos TH et al. Effect of serial levosimendan infusions on left ventricular performance and plasma biomarkers of myocardial injury and neurohormonal and immune activation in patients with advanced heart failure. Heart. 2006;92(1):1768-72
  3. Buckberg GD, Brazier JR, Nelson RL, Goldstein SM, McConnell DH, Cooper N. Studies of the effects of hypotermia on regional myocardial flow and metabolism during cardiopulmonary bypass. The adequately perfused beating, fibrilating and arrested heart. J Thorac Cardiovas Surg. 1977;73(1):87-94
  4. Akgün S. Erişkin kalp cerrahisinde miyokard korunması. In: Duran E, ed. Kalp ve Damar Cerrahisi. 1st ed. İstanbul. Çapa Tıp Kitabevi, 2004:1091-106
  5. Buckberg GD. The duality of cardiac surgery: mechanical and metabolic objctive. In: Salerno TA, Ricci M, eds. Myocardial Protection. 1st ed. New Jersey. Blackwell Publishing, 2004:13-7
  6. Carden DL, Granger DN. Pathophysiology of ischemia reperfusion injury. J Pathol. 2000;190(6):255-66
  7. Dhalla NS, Elmoselhi AB, Hata T, Makino N. Status of myocardial antioxidants in ischemia-reperfusion injury. Cardivasc Res. 2000;47(3):446-56
  8. Reiter RJ, Tan DX. Melatonin: A novel protective agent against oxidative injury of the ischemic-reperfused heart. Cardiovascular Research. 2003;58(1):10-9
  9. Gross GJ, Kersten JR, Warltier DC. Mechanisms of postischemic contractile dysfunction. Ann Thorac Surg. 1999;68(5):1898-904
  10. Jordan JE, Zhao ZQ, Vinten-Johansen J. The role of neutrophils in myocardial ischemia- reperfusion injury. Cardiovasc Res. 1999;43(4):860-78
  11. Reiter RJ. The aging pineal and its physiological consequences. BioEssays. 1992;14(3):169-75
  12. Efthimiadis A, Cheiridou M, Lefkos N, Doumalas A, Arampatzis P, Tsapas G. The predictive value of TnT in patients who underwent an extracardiac surgery operation. Acta Cardiol. 1995;50(4):309-13
  13. Hamm CW, Katus HA. New biochemical markers for myocardial cell injury. Curr Opin Cardiol. 1995;10(4):355-60
  14. Bertinchont JP, Larue C, Pernel I, Ledermann B, Fabbro-Peray P, Beck L et al. Release kinetics of serum cardiac troponin I in ischemic myocardial injury. Clin Biochem. 1996;29(6):587-94
  15. Collinson PO. Troponin T or troponin I or CK-MB (or