SavedAdd your journal

Journals / Turkish Journal of Hematology / 2008 / Cilt: 25 - Sayı: 1

Türk toplumunda gözlenen Hb D-Ouled Rabah [beta19(B1) Asn>Lys] olgusu

First observation of Hb D-Ouled Rabah [beta19(B1) Asn>Lys] in the Turkish population

Aylin KÖSELER
ANZEL BAHADIR
Hasan KOYUNCU
AYFER ATALAY
EROL ÖMER ATALAY
Pages
51–53
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Our report describes the first observation of this hemoglobin variant in the Turkish population.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Hb D-Ouled Rabah [beta19(B1)Asn>Lys] is a rare hemoglobin (Hb) beta chain variant reported from Tuareg tribes in Algeria and once from China.
📊
Key Findings & Data:It was suggested that Hb D-Ouled Rabah might be specific of Berber-speaking populations.
💡
Conclusion & Impact:Our report describes the first observation of this hemoglobin variant in the Turkish population.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Hemoglobinler · anormal · Erkek

Abstract

Hb D-Ouled Rabah [beta19(B1)Asn>Lys] is a rare hemoglobin (Hb) beta chain variant reported from Tuareg tribes in Algeria and once from China. It was suggested that Hb D-Ouled Rabah might be specific of Berber-speaking populations. Our report describes the first observation of this hemoglobin variant in the Turkish population.

Özet

Hb D-Ouled Rabah [beta19(B1)Asn>Lys] Cezayirdeki Tuareg kabilelerinde bildirilen nadir bir hemoglobin varyantıdır. Her ne kadar Çinde de bir olgu bildirilmiş olsa dab u hemoglobin varyantının sadece Berberce konuşan toplumlarda bulunabileceği konusunda bir görüş bulunmaktadır. Bu çalışmada Hb D-Ouled Rabah [beta19(B1)Asn>Lys] Türkiye'de ilk kez bildirilmektedir.

🔖

Cite This Article

KÖSELER, A., BAHADIR, A., KOYUNCU, H., ATALAY, A., ATALAY, E. Ö. (2008). Türk toplumunda gözlenen Hb D-Ouled Rabah [beta19(B1) Asn>Lys] olgusu. Turkish Journal of Hematology, Cilt: 25 - Sayı: 1, 51–53. https://ajindex.com/articles/413048

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (10)

  1. Elion J, Belkhodja O, Wajcman H, Labie D. Two variants of hemoglobin D in the Algerian population: hemoglobin D Ouled Rabah 19 (BI) Asn leads to Lys and hemoglobin D Iran 22 (Br) Glu leads to Gln. Biochim Biophys Acta. 1973;15:310:360-4
  2. Mauran-Sendrail A, Lefevre-Witier, Lehmann H, Casey R. Haemoglobin D Ouled Rabah (beta 19[Bl] asn leads to lys) in a Tuareg tribe of the Southern Sahara. J Med Genet 1977;14:245-9
  3. Ren Y, Chen SS, Liang CC, Zhang MJ, Huang MX, Zhang GL, Zen XS. Hb D-Ouled Rabah [beta 19(B1)Asn>Lys]. A rare beta chain variant found in a Chinese family. Hemoglobin. 1988;12:77-9
  4. Merghoub T, Sanchez-Mazas A, Tamouza R, Lu CY, Bouzid K, Ardjoun FZ, Labie D, Lapouméroulie C, Elion J. Haemoglobin D-Ouled Rabah among the Mozabites: a relevant variant to trace the origin of Berber-speaking populations. Eur J Hum Genet 1997;5:390-6
  5. Altay Ç. Abnormal hemoglobins in Turkey. Turk J Hematol 2002;19:63-74
  6. Köseler A, Atalay A, Koyuncu H, Turgut B, Bahadır A, Atalay EÖ. Molecular identification of a rare hemoglobin variant, Hb J-Iran [beta77(EF1)His>Asp] in Denizli province of Turkey.Turk J Hematol 2006;23:164-6
  7. British Committee for Standards in Haematology. Guideline: The laboratory diagnosis of hemoglobinopathies. Br J Hematol 1998;101:783-92
  8. Atalay EÖ, Koyuncu H, Turgut B, Atalay A, Yıldız S, Bahadır A, Köseler A. High incidence of HbDLos Angeles [beta 121(GH4)Glu>_Gln] in Denizli Province, Aegean region of Turkey. Hemoglobin 2005;29(4):307-10
  9. Atalay A, Koyuncu H, Köseler A, Özkan A, Atalay EÖ. Hb Beograd [beta 121(GH4)Glu>Val, GAA> GTA] in the Turkish population. Hemoglobin 2007;31(4):000-000 (accepted and scheduled for publication)
  10. Akar N, Akar E, Özdemir S. A further case of Hb J Iran [beta77(EF1)His>Asp] in Muğla, Turkey. Turk J Hematol 2007;24:37-38.