Journals / Turkish Journal of Hematology / 2012 / Cilt: 29 - Sayı: 2

Serebellar granülositik sarkom: Bir olgu sunumu

Cerebellar granulocytic sarcoma: A case report

Pages
177–180
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Herein, we report a four year old boy with cerebellar localization of granulocytic sarcoma.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Granulocytic sarcoma is a rare tumor composed of immature granulocytic cells that is usually associated with acute myelogenous leukemia.
📊
Key Findings & Data:The mechanisms of intraparenchymal cranial localization of GS remains unknown, as only 10 cases with cerebellar granulocytic sarcoma have been previously reported.
💡
Conclusion & Impact:Herein, we report a four year old boy with cerebellar localization of granulocytic sarcoma.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Granulocytic sarcoma is a rare tumor composed of immature granulocytic cells that is usually associated with acute myelogenous leukemia. Intraparenchymal cranial localization without skull, meningeal, or bone marrow invasion is extremely rare. The mechanisms of intraparenchymal cranial localization of GS remains unknown, as only 10 cases with cerebellar granulocytic sarcoma have been previously reported. Herein, we report a four year old boy with cerebellar localization of granulocytic sarcoma.

Özet

Granulositik sarkom, genellikle akut myelositer lösemiye eşlik eden immatür granülositik hücrelerden oluşan nadir bir tümördür. Kafatası, meninks ve kemik iliği tutulumu olmaksızın izole intrakranial parankimal tutulum ise çok daha nadirdir ve mekanizması henüz tam olarak bilinmemektedir. Literatürde 10 vaka bildirilmiştir. Bu raporumuzda kemik iliği tutulumu olmadan izole serebellar parankimde yer alan granülositik sarkom tartışılmıştır.

🔖

Cite This Article

BAYTAN, B., EVİM, M. S., GÜNEŞ, A. M., KOCAELİ, H., BALABAN, Ş., KORFALI, E., TÜZÜNER, N. (2012). Serebellar granülositik sarkom: Bir olgu sunumu. Turkish Journal of Hematology, Cilt: 29 - Sayı: 2, 177–180. https://ajindex.com/articles/412883

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (1)

  1. Byrd JC, Edenfield WJ, Shields DJ, Dawson NA: Extramedullary myeloid cell tumors in acute nonlymphocytic leukemia: A clinical review. J Clin Oncol 1995; 13: 1800- 1816 2. Byrd JC, Edenfield WJ, Dow NS, Aylesworth C, Dawson N: Extramedullary myeloid cell tumors in myelodysplastic- syndromes: Not a true indication of impending acute myeloid leukemia. Leuk Lymphoma 1996; 21: 153-159 3. Mahendra P, Ager S, Bedlow AJ, Bloxham DM, Green AR, Marcus RE: Two unusual neurological presentations of granulocytic sarcoma in Philadelphia positive chronic myeloid leukaemia. Leuk Lymphoma 1994; 15: 351-355 4. Byrd JC, Weiss RB, Arthur DC, Lawrence D, Baer MR, Davey F, Trikha ES, Carroll AJ, Tantravahi R, Qumsiyeh M, Patil SR, Moore JO, Mayer RJ, Schiffer CA, Bloomfield CD: Extramedullary leukemia adversely affects hematologic complete remission rate and overall survival in patients with t(8;21)(q22;q22): Results from Cancer and Leukemia Group B 8461. J Clin Oncol 1997; 15: 466-475 5. Neiman RS, Barcos M, Berard C, Bonner H, Mann R, Rydell RE, Bennett JM: Granulocytic sarcoma: A clinic pathologic study of 61 biopsies cases. Cancer 1981; 48: 1426-1437 6. Barnett MJ, Busman WV: Granulocytic sarcoma of the brain: A case report and review of the literature. Radiology 1986; 160: 223-225 7. O’Brien J, Buckley O, Murphy C, Torreggiani WC: An unusual cause of persistent headache: Chloroma (2008: 2b). Eur Radiol 2008; 18: 1071-1072 8. Aki H, Baslar Z, Uygun N, Ozguroglu M, Tuzuner N: Primary granulocytic sarcoma of the urinary bladder: Case report and review of the literature. Urology 2002; 60: 345 9. Cavdar AO, Arcasoy A, Babacan E, Gözdaşoğlu S, Topuz U, Fraumeni JF Jr: Ocular granulocytic sarcoma (chloroma) with acute myelomonocytic leukemia in Turkish children. Cancer 1978; 41(4): 1606-1609 10. Cavdar AO, Babacan E, Gözdaşoğlu S, Kilicturgay K, Arcasoy A, Cin S, Ertem U, Erten J: High risk subgroup of acute myelomonocytic leukemia (AMML) with orbito-ocular granulocytic sarcoma (OOGS) in Turkish children. Retrospective analysis of clinical, hematological, ultrastructural and therapeutical findings of thirty-three OOGS. Acta Haematol 1989; 81: 80-85 11. Cavdar AO, Babacan E, Gözdasoglu S, Yavuz G, Unal E, Pamir A: T-lymphocyte sub-populations in orbito-ocular granulocytic sarcoma (OOGS) and acute myelocytic leukemia (AML): A preliminary study. Med Oncol Tumor Pharmacother 1993; 10: 113-115 12. Hiçsönmez G, Cetin M, Tuncer AM, Yenicesu I, Aslan D, Ozyürek E, Unal S: Children wit