SavedAdd your journal

Journals / Turkish Journal of Gastroenterology / 1999 / Cilt: 10 - Sayı: 3

Hemorrhagic colitis due to ampicillin-sulbactam: A report of four cases

Ampisilin sulbaktama bağlı gelişen hemorajik kolit: 4 olgu nedeniyle

Gürden GÜR
Ünser ARIKAN
Ayhan ÇEKİN
Murat GÜRSOY
Yücel ÜSTÜNDAĞ
Beyhan DEMİRHAN
Çağlar BAYSAL
Sedat BOYACIOĞLU
Pages
207–210
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this study, we present four hemorrhagic colitis cases caused by ampicillin- sulbactam.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Ampicillin and other penicillin derivatives may cause hemorrhagic colitis, whose characteristic features are mucosal hemorrhage and edema, and which presents with bloody diarrhea.
📊
Key Findings & Data:It generally affects the right colon, but occasionally the entire colon may be involved.
💡
Conclusion & Impact:In this study, we present four hemorrhagic colitis cases caused by ampicillin- sulbactam.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Gastrointestinal kanama · Ampisilin · Kolit

Abstract

Ampicillin and other penicillin derivatives may cause hemorrhagic colitis, whose characteristic features are mucosal hemorrhage and edema, and which presents with bloody diarrhea. It generally affects the right colon, but occasionally the entire colon may be involved. Cessation of antibiotic therapy results in clinical improvement and specific therapy is not neccessary. In this study, we present four hemorrhagic colitis cases caused by ampicillin- sulbactam.

Özet

Hemorajik kolit, ampisilin başta olmak üzere penisilin türevleri kullanımına bağlı olarak ani olarak ortaya çıkabilen ve kanlı ishalin belirgin olduğu bir klinik tablodur. Çoğunlukla sağ kolon tutulumu izlenmekle birlikte tüm kolonun tutulduğu vakalara da rastlanabilmektedir, Histolojik olarak, mukozal hemoraji ve ödem belirgindir. Spesifik tedaviye gereksinim duyulmadan, antibiyotiğin kesilmesini takiben düzelme izlenmektedir. Bu çalışmamızda oral ampisilin sulbaktam kullanımına bağlı olarak gelişen 4 hemorajik kolit vakasını sunmaktayız.

🔖

Cite This Article

GÜR, G., ARIKAN, Ü., ÇEKİN, A., GÜRSOY, M., ÜSTÜNDAĞ, Y., DEMİRHAN, B., BAYSAL, Ç., BOYACIOĞLU, S. (1999). Hemorrhagic colitis due to ampicillin-sulbactam: A report of four cases. Turkish Journal of Gastroenterology, Cilt: 10 - Sayı: 3, 207–210. https://ajindex.com/articles/410981

References (10)

  1. Gould PC, Khawaja FI, Rosenthal WS. Antibiotic associated hemorrhagic colitis. Am J Gastroenterol 1982; 77: 491-3
  2. Moulis H, Vender RJ. Antibiotic associated hemorrhagic colitis. J Clin Gastroenterol 1994;18: 227-31
  3. Matsumoto T, Iida M, Metsui T. Ultrasonic and CT findings in penicillin induced non pseudomembranous colitis. Gastrointest Radiol 1990; 15: 329-32
  4. Choulot JS, Pariente EA, Beze P, Saint Martin J, Mensire A. Acute hemorrhagic colitis after intake of amoxicillin. Arch Pediatr 1996; 3: 508-9
  5. Kato S, Ebina K, Ozawa A, Naganuma H, Nakagawa H. Antibiotic associated hemorrhagic colitis without Clostridium difficile toxin in children. J Pediatr 1995; 126: 1008-10
  6. Sakurai Y, Tsuchiya H, Ikegami F. Acute right sided he-morrhagic colitis associated with oral administration of ampicilline. Dig Dis Sci 1979; 24: 910-5
  7. Mc Kinley M, Toffler RB. Antibiotic associated hemorrha-gic colitis. Dig Dis Sci 1980; 25: 812-3
  8. Su C, Brandt LJ. Escherichia coli 0157:H7 infection in humans. Ann Int Med 1995; 123: 698-714
  9. Samadpour M. Molecular epidemiology of E. coli O157:H7 by restriction fragment length polymorphism using Shiga like toxin genes. J Clin Microbiol 1995; 33: 2150-4
  10. Tarr PI. Escherichia coli O157:H7:clinical, diagnostic and epidemiological aspects of human infection. Clin Infect Dis 1995; 20: 1-8.