Journals / Turkish Journal of Gastroenterology / 2001 / Cilt: 12 - Sayı: 3

Dispeptik olgularda "İncisura angularis" biopsisinin özellikleri

Features of incisura angularis biopsies in dyspeptic cases

Pages
211–213
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: It is considered that taking a fifth biopsy from the incisura angularis may be advantageous in detecting early stage MALT lymphoma.

📌 3 Key Takeaways

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Objective & Hypothesis:Background/aims: In the Updated Sydney Classification for gastritis the incisura angularis, where the metaplasia-dysplasia sequence is frequently observed, has been recommended as a fifth biopsy region in addition to four biopsies taken from gastric antrum and corpus.
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Key Findings & Data:Methods: The gastric biopsies of 150 cases with dyspeptic complaints were re-examined.
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Conclusion & Impact:Conclusion: It is considered that taking a fifth biopsy from the incisura angularis may be advantageous in detecting early stage MALT lymphoma.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Biyopsi · Geriyedönük çalışma · Araştırma teknikleri

Abstract

Background/aims: In the Updated Sydney Classification for gastritis the incisura angularis, where the metaplasia-dysplasia sequence is frequently observed, has been recommended as a fifth biopsy region in addition to four biopsies taken from gastric antrum and corpus. The aim of this study was to evaluate the necessity and value of this recommendation. Methods: The gastric biopsies of 150 cases with dyspeptic complaints were re-examined. According to the parameters of the Updated Sydney Classification, activity, mononuclear inflammatory infiltration, atrophy and intestinal metaplasia were evaluated on routine haematoxylin-eosin preparations. Toluidin blue was used to detect Helicobacter pylori. The presence of lymphoid follicles was also examined. Antrum+corpus findings and antrum+corpus+incisura angularis findings were compared using c2 test. Results: The only significant difference between the two groups was the presence of lymphoid follicles (p=0.036), while Helicobacter pylori (p=0.634), activity (p=0.12) atrophy (p=0.579) and intestinal metaplasia (p=0.56) were insignificant. Conclusion: It is considered that taking a fifth biopsy from the incisura angularis may be advantageous in detecting early stage MALT lymphoma.

Özet

Amaç: Güncelleştirilmiş Sydney Sınıflaması'nda, antrum ve korpusun küçük ve büyük kurvatürlerinden alınacak dört standart biopsi yanı sıra, beşinci bir biopsi bölgesi olarak metaplazi-displazi geçişinin sık rastlandığı bölge olan incisura angularisten de biopsi alınması önerilmektedir. Çalışmamızda incisura angularis biopsisinin anlamı ve gerekli olup olmadığı araştırılmıştır. Yöntem: Retrospektif olarak, dispepsi yakınması nedeniyle gastroenteroloji kliniğine başvuran ve endoskopi uygulanan 150 olgunun antrum, korpus ve incisura angularis biopsileri incelendi. Toluidin blue ile Helikobakter pilori; rutin hematoksilen-eozin boyamada aktivite, mononükleer yangısal infiltrasyon, atrofi ve metaplazi kriterleri Güncelleştirilmiş Sydney Sınıflaması'na göre değerlendirildi. Ayrıca lenfoid follikül yapısı bulunup bulunmadığı araştırıldı. Antrum+korpus bulguları ve antrum+ korpus + incisura angularis bulguları c2 testiyle karşılaştırıldı. Bulgular ve sonuç: İki grup arasında Helicobacter pylori (p=0,634), aktivite (p=0,12) atrofi (p=0,579), intestinal metaplazi (p=0,56) açısından istatistiksel anlamlı ilişki bulunmazken, lenfoid folliküller açısından istatistiksel anlam saptandı (p=0,036). Antrum ve korpusa ek olarak incisura angularisten biopsi alınmasının MALT lenfomasının erken evrede saptanması açısından, uygun olabileceği düşünülmektedir.

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Cite This Article

DEMİR, M. A., NEŞE, N., SARUÇ, M., YÜCEYAR, H., AYHAN, S. (2001). Dispeptik olgularda "İncisura angularis" biopsisinin özellikleri. Turkish Journal of Gastroenterology, Cilt: 12 - Sayı: 3, 211–213. https://ajindex.com/articles/410948

References (17)

  1. Elta GH, Appelman HD, Behler EM, et al. A study of correlation between endoscopic and histopathological diagnosis in gastroduodenitis. Am J Gastroenterol 1987; 82: 749-53
  2. Bronner MP, Haggitt RC, Rubin CE. Endoscopy and endoscopic biopsy. In: Ming SC, Goldman H, eds. Pathology of the gastrointestinal tract. 2nd ed. Pennsylvania: Williams & Wilkins Co., 1998; 35-46
  3. Price AB. The Sydney System: histological division. J Gastroenterol Hepatol 1991; 6: 209-22
  4. Dixon MF, Genta RM, Yardley JH, et al. Classification and grading of gastritis: an updated Sydney System. Am J Surg Pathol 1996; 20: 1161-81
  5. Stemmerman GN. Intestinal metaplasia of stomach: a status report. Cancer 1994: 74; 556-64
  6. Sugimura T, Sugano H, Terada M, et al. First Internati-onal Workshop of the Princess Takamatsu Cancer Research Fund: intestinal metaplasia and gastric cancer. Mol Carcinog 1994; 11: 1-7
  7. Hansson LE, Engstrand L, Nyren O, Lindgren A. Prevalance of helicobacter pylori infection in subtypes of gastric cancer. Gastroenterology 1995; 109: 885-8
  8. Correa P. Helicobacter pylori and gastric carcinogenesis. Am J Surg Pathol 1995; 19: 37-43
  9. Sipponen PH. Gastric cancer: a long term consequence of Helicobacter pylori infection? Scand J Gastroenterol 1994; 201: 24-7
  10. Genta RM, Hamner HW, Graham DY. Gastric lymphoid follicles in Helicobacter pylori infection: frequency, distribution and response to triple therapy. Hum Pathol 1993; 24: 577-83
  11. Wotherspoon AC, Ortiz-Hidalgo C, Falzon MR, Isaacson PG. Helicobacter pylori-associated gastritis and primary B-cell gastric lymphoma. Lancet 1991; 338: 1175-6
  12. Isaacson PG. Gastrointestinal lymphoma. Hum Pathol 1994; 25: 1020-9
  13. Ming SC. Tumors of the esophagus and stomach. In: Armed Forces Institute of Pathology Atlas of tumor pathology, second series, fasicle 7. Washington DC: 1973; 82
  14. Japanese Resarch Society For Gastric cancer. Japanese classification of gastric cancer. Tokyo: Kanehara; 1995. In: Ming SC, Goldman H, eds. Pathology of the gastrointestinal tract. 2nd ed. Pennsylvania: Williams & Wilkins Co., 1998; 621
  15. Aoki K. Epidemiology of stomach cancer. In: Nishi M, Ichikawa H, Nakajima T, et al., eds. Gastric cancer. Tokyo: Springer, 1993; 2-15
  16. Isaacson PG. Lymphoproliferative disorders of the gastrointestinal tract. In: Ming SC, Goldman H, eds. Pathology of the gastrointestinal tract. 2nd ed. Pennsylvania: Williams & Wilkins Co., 1998; 339-60
  17. Antonioli DA. Precusors of gastric car