AI Summary & Key Takeaways
AI InsightWe present the case of a patient with alverine induced hepatotoxicity and cholestasis, which has only seldomly been reported in the literature.
📌 3 Key Takeaways
Abstract
Drug-induced hepatotoxicity is an important cause of hepatocellular injury. Hepatic necrosis may range from asymptomatic elevations in transaminases to fulminant hepatic failure and death. Alverine is an antispasmodic drug which is especially used in patients with irritable bowel syndrome. Only a few cases of alverine associated hepatotoxicity have been reported previously. We present the case of a patient with alverine induced hepatotoxicity and cholestasis, which has only seldomly been reported in the literature.
Özet
İlaca bağlı hepatotoksisite hepatosellüler hasarın önemli nedenlerinden biridir. Hepatik nekroz hafif transaminaz yüksekliklerinden fulminan hepatite ve ölüme kadar değişen derecelerde olabilir. Alverine, özellikle irritabl barsak sendromu olan hastalarda anti-spazmodik olarak kullanılmaktadır. Alverine'e bağlı hepatotoksisite çok nadir bildirilmiştir. Alverine'e bağlı akut hepatit ve kolestazla seyreden toksik hepatit olgumuz, literatürde bu tür vakaların çok nadir olması nedeni ile ilginç bulunarak sunulmuştur.