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Journals / Turkish Journal of Gastroenterology / 2004 / Cilt: 15 - Sayı: 3

Türk hastalarda liken planus ve hepatit C virus enfeksiyonu

Lichen planus and HCV infection in Turkish patients

Didem KARAVELİOĞLU
Elif Sare KOYTAK
Hakan BOZKAYA
Özden UZUNALİMOĞLU
A. Mithat BOZDAYI
Cihan YURDAYDIN
Pages
133–136
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusions: The results of this study suggest that no relationship exists between hepatitis C virus infection and lichen planus among Turkish patients.

📌 3 Key Takeaways

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Objective & Hypothesis:Background/aims: A relation between hepatitis C virus (HCV) infection with lichen planus (LP) has been reported in the literature but remains controversial.
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Key Findings & Data:Methods: Forty-one cases of LP diagnosed at the Dermatology Clinic of our hospital between March 1995 and May 1996 were evaluated (22 men and 19 women; mean age 41.6 years).
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Conclusion & Impact:Conclusions: The results of this study suggest that no relationship exists between hepatitis C virus infection and lichen planus among Turkish patients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Liken planus · Epidemiyoloji · Hepatit C

Abstract

Background/aims: A relation between hepatitis C virus (HCV) infection with lichen planus (LP) has been reported in the literature but remains controversial. To find out the prevalence of HVC infection among patients with LP. Methods: Forty-one cases of LP diagnosed at the Dermatology Clinic of our hospital between March 1995 and May 1996 were evaluated (22 men and 19 women; mean age 41.6 years). They were screened for the presence of HBsAg, anti HBs, and anti-HCV by ELISA and HCV-RNA by nested polymerase chain reaction (PCR). Blood donors registered in Ankara University İbni Sina Hospital Blood Bank were used as a control group. Results: Of the 41 LP patients, 2 (4.8%) had anti-HCV positivity together with HCV-RNA positivity. Twelve patients (29.2%) had anti-HBs and 3 patients (7.3%) had HBsAg positivity. In blood donors, anti-HCV positivity prevalence was 2.5%. Conclusions: The results of this study suggest that no relationship exists between hepatitis C virus infection and lichen planus among Turkish patients.

Özet

Amaç: Literatürde hepatit C virüsü (HCV) enfeksiyonu ile liken planus (LP) arasında bir ilişki olduğu bildirilmiştir fakat halen sonuçlar çelişkilidir. Türk LP hastalarında HCV enfeksiyonu sıklığını saptamak. Yöntem: Mart 1995 ile Mayıs 1996 tarihleri arasında hastanemizin Dermatoloji Kliniği’ne başvuran 41 liken planus hastası (22 erkek, 19 kadın; ortanca yaşları 41.6) değerlendirildi. Hastalarda HBsAg, anti-HBs, anti-HCV varlığı ELISA yöntemi ile ve HCV-RNA varlığı nested-PCR yöntemi ile araştırıldı. Kontrol grubu olarak Ankara Üniversitesi İbni Sina Hastanesi Kan Bankası’na kayıtlı olan kan donörleri kullanıldı. Bulgular: 41 LP hastasının 2’sinde (% 4.8) anti-HCV ve HCV-RNA birlikte pozitif saptandı. 12 hastada (% 29.2) anti-HBs, 3 hastada (% 7.3) HBsAg pozitif saptandı. Kan donörlerinde anti-HCV pozitiflik sıklığı % 2.5 olarak bulundu. Sonuç: Bu çalışma sonucunda Türk hastalarda hepatit C virüsü enfeksiyonu ile liken planus arasında anlamlı bir ilişki saptanmamıştır.

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Cite This Article

KARAVELİOĞLU, D., KOYTAK, E. S., BOZKAYA, H., UZUNALİMOĞLU, Ö., BOZDAYI, A. M., YURDAYDIN, C. (2004). Türk hastalarda liken planus ve hepatit C virus enfeksiyonu. Turkish Journal of Gastroenterology, Cilt: 15 - Sayı: 3, 133–136. https://ajindex.com/articles/410425

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