Journals / Turkish Journal of Gastroenterology / 2006 / Cilt: 17 - Sayı: 4

Ameliyat öncesi kan transfüzyonunun kolorektal kanserde morbidite ve sağkalıma etkisi

The effect of preoperative blood transfusion on morbidity and survival in colorectal malignancy

Pages
283–287
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Preoperative transfusion during surgery for colorectal malignancy does not result in an increase in postoperative complications, long-term failure or death rates.

📌 3 Key Takeaways

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Objective & Hypothesis:Background/aims: It is believed that blood transfusions adversely affect colorectal cancer surgery.
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Key Findings & Data:Methods: The records of 333 patients who were operated for colorectal malignancy between 1980 and 1995 were evaluated.
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Conclusion & Impact:Conclusion: Preoperative transfusion during surgery for colorectal malignancy does not result in an increase in postoperative complications, long-term failure or death rates.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Kan nakli · Hastalıksız sağkalım · Sağkalım oranı

Abstract

Background/aims: It is believed that blood transfusions adversely affect colorectal cancer surgery. However, intra- and postoperative blood transfusions represent urgent interventions, and immeasurable confounding factors may affect the shortand long-term outcome. Therefore, we compared colorectal cancer patients who had received preoperative blood transfusion with patients who did not receive transfusions with regard to postoperative complications and long-term outcome. Methods: The records of 333 patients who were operated for colorectal malignancy between 1980 and 1995 were evaluated. Results: Sixty-one patients (18.3%) received preoperative blood transfusions. Wound infection rate was higher (14.2% vs 1.9%) in the no-transfusion group. Disease-free survival was not different between the groups (p=0.134). Cumulative survival was adversely affected in the preoperative transfusion group (p=0.012). However, preoperative blood transfusion did not emerge to be an independent factor for wound infection or for death on follow-up when the confounding factors were corrected. Conclusion: Preoperative transfusion during surgery for colorectal malignancy does not result in an increase in postoperative complications, long-term failure or death rates.

Özet

Kolorektal kanser cerrahisinde kan transfüzyonunun hastayı olumsuz etkilediği düşünülmektedir. Ancak ameliyat sırasında ve sonrasında yapılan transfüzyonlar acil kabul edilen girişimler olup transfüzyon dışında birçok ölçülemeyecek etken kısa ve uzun dönem sonuçlarda etkili olabilir. Bu nedenle kolorektal kanserli hastalarda daha elektif bir girişim olan ameliyat öncesi kan transfüzyonunun ameliyat sonrası kompli-kasyonlara ve uzun dönem sağkalıma etkisini araştırdık. Yöntem: 1980-1995 yılları arasında kolorektal kanser nedeniyle ameliyat edilen 333 hastanın kayıtları geriye dönük olarak incelendi. Bulgular: Altmışbir hastaya (%18.3) ameliyat öncesi kan transfüzyonu yapıldı. Yara enfeksiyonu kan transfüzyonu yapılmayan grupta daha fazla idi (%14.2'ye karşı %1.9). Hastalıksız sağkalım iki grup arasında farklı değildi (p=0.134). Toplam sağkalım ameliyat öncesi transfüzyon yapılan grupta daha kötü idi (p-0.012). Ancak etkisi olabilecek diğer etkenlerin düzeltilmesinden sonra ameliyat öncesi kan transfüzyonunun yara enfeksiyonu ve uzun dönemde ölüm riskine etkisi olmadığı gösterildi. Sonuç: Serimizde ameliyat öncesi kan transfüzyonunun kolorektal kanser cerrahisinde komplikasyon artışına, hastalık yinelemesine ve ölüm oranına etkili olmadığı belirlenmiştir.

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Cite This Article

NURSAL, T. Z., HAMALOĞLU, E. (2006). Ameliyat öncesi kan transfüzyonunun kolorektal kanserde morbidite ve sağkalıma etkisi. Turkish Journal of Gastroenterology, Cilt: 17 - Sayı: 4, 283–287. https://ajindex.com/articles/410374

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