Journals / Ulusal Travma Dergisi / 2003 / Cilt: 9 - Sayı: 1

Intraabdominal and intramural hemorrhage due to warfarin therapy

Warfarin'e bağlı gelişen karın içi ve barsak duvarı kanamaları

Pages
50–53
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Blood and plasma replacements are first line of supportive treatment and surgery should be avoided if possible.

📌 3 Key Takeaways

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Objective & Hypothesis:Background: The study investigated clinical, radiological findings and treatment methods used in patients who developed intraabdominal hemorrhage due to chronic warfarin use.
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Key Findings & Data:Results: Abdominal ultrasonography and computerized tomography identified the individuals' problems as intraabdominal hemorrhage (n=2j, intestinal intramural and intraabdominal hemorrhage (n-2), bleeding into the sheath of the rectus abdominus muscle (n=l), subcapsular splenic hemorrhage (n-l), and bleeding due to ruptured ovarian cyst (n=2).
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Conclusion & Impact:Blood and plasma replacements are first line of supportive treatment and surgery should be avoided if possible.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Geriyedönük çalışma · Kanama · Ultrasonografi

Abstract

Background: The study investigated clinical, radiological findings and treatment methods used in patients who developed intraabdominal hemorrhage due to chronic warfarin use. Patients and methods: Eight patients receiving warfarin for cardiac valve replacement, pulmonary thromboemboli, and atrial fibrillation were admitted to our hospital. The patients had abdominal pain, nausea, and vomiting although there was no hematemesis and melena. Results: Abdominal ultrasonography and computerized tomography identified the individuals' problems as intraabdominal hemorrhage (n=2j, intestinal intramural and intraabdominal hemorrhage (n-2), bleeding into the sheath of the rectus abdominus muscle (n=l), subcapsular splenic hemorrhage (n-l), and bleeding due to ruptured ovarian cyst (n=2). Conclusions: Clinicians must be alert for intraabdominal bleeding in patients who are prescribed war-farin treatment. Abdominal ultrasonography and computerized tomography should be used to investigate all such cases of suspected hemorrhage. Blood and plasma replacements are first line of supportive treatment and surgery should be avoided if possible.

Özet

Amaç: Bu çalışmada kalp kapak replasmanı, pulmoner tromboemboli veya atrial fibrillasyon nedeniyle warfarin tedavisi verilen ve karın içi veya barsak duvarına kanama tespit edilen sekiz hastanın klinik ve radyolojik bulguları ile tedavi yöntemleri sunulmuştur. Gereç ve Yöntem: Başkent Üniversitesi Adana Hastanesi Genel Cerrahi Bölümünde Ocak 1999 ile Temmuz 2001 tarihleri arasında akut karın bulguları olan melena veya hematemezi olmayan ve warfarin kullanan 8 hasta retrospektif olarak gözden geçirilmiştir. Bulgular: Yapılan tetkikler sonucunda iki hastada karın içine, iki hastada hem karın içine hem de ince barsak duvarında (intramural), iki hastada över kist rüptürüne bağlı karın içi kanama, bir hastada karın ön duvarında, bir hastada ise dalakta subkapsüler kanama saptanmıştır. Tüm hastalar tıbbi tedavi ile düzelmiştir. Sonuç: Warfarin kullanan hastalarda karın içi kanama komplikasyonu gelişebileceği akılda tutulmalı ve kanama düşünülen olgularda acil abdominal ultrasonografi ve gerekirse bilgisayarlı tomografi tetkiki planlanmalıdır. Tedavi, öncelikle kan ve plazma transfüzyonu şeklinde destek tedavisi olarak planlanmalı ve cerrahi girişimden mümkün olduğunca kaçınılmalıdır.

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Cite This Article

TARIM, A., YILDIRIM, S., NURSAL, T. Z., NOYAN, T. (2003). Intraabdominal and intramural hemorrhage due to warfarin therapy. Ulusal Travma Dergisi, Cilt: 9 - Sayı: 1, 50–53. https://ajindex.com/articles/324979

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References (12)

  1. Hill J,Kassam S. Ovarian hemorrhage in ovulating women receiving anticoagulant therapy. J Rep Med 1984;29(3):205-8
  2. Honore LH: Ovarian hemorrhage: A complication of long term anticoagulant therapy. West J Med 1980;132:460
  3. Hirsh J, Dalen JE, Deykin D, Poller L. Oral anticoagulants: mechanism of action, clinical effectiveness, and optimal therapeutic range. Chest. 1992;102 (suppl):312S326S
  4. Landefeld S, Beyth R. Anticoagulant-related bleeding: Clinical epidemiology, prediction, and prevention. Am J Med 1993;95:315-328
  5. Penning-van Beest FJ, van Meegen E, Rosendaal FR, Stricker BH. Drug interactions as a cause of over anticoagulation on phenprocoumon or acenocoumarol predominantly concern antibacterial drugs. Clin Pharmacol Ther 2001;69(6):451-7 6. Choudari CP, Rajgopal C, Palmer KR. Acute gastrointestinal haemorrhage in anticoagulated patients: diagnoses and response to endoscopic treatment. Gut 1994;35:464-466
  6. White R, McKittrick T, Takakuwa J. Management and prognosis of life threatening bleeding during warfarin therapy. Arch Intern med.1996:156;1197-1200
  7. Bradlow BA. Warfarin therapy – a practical guide. S Afr Med J 1983;64:317-319
  8. Elaine MH, YuChiao Chang, Skates SJ, et al. Prospective study of the outcomes of ambulatory patients with excessive warfarin anticoagulation.Arch Intern Med 2000;160:1612-1617
  9. Phillip RS: Massive intraperitoneal hemorrhage from a ruptured ovarian cyst secondary to anticoagulant therapy. J Reprod Med 1979;22:82
  10. Daves RS, Goh GJ, Curtis JM, Lewis-Jones HG. Abdominal wall haematoma in anti-coagulated patients: the role of imaging in diagnosis. Australas Radiol. 1996;40(2):109-12
  11. Tresch DD, Halverson G, Blick M et al.Ovarian (corpus luteum) hemorrhage during anticoagulation therapy. Ann Intern Med 1978;88:642
  12. Phillip RS. Massive intraperitoneal hemorrhage from a ruptured ovarian cyst secondary to anticoagulant therapy for recurrent pulmonary emboli. Am J Obstet Gynecol 1978;130:231.