Journals / Turkish Journal of Gastroenterology / 2008 / Cilt: 19 - Sayı: 2

Digitalisin neden olduğu, anjiografik olarak kanıtlanan non oklusiv mezenterik iskemili bir olgu

A case of angiographically verified non-occlusive mesentery ischemia induced by digitalis

Pages
125–128
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, nonocclusive mesentery ischemia should be included in the differential diagnosis for patients who develop sudden and diffuse abdominal pain while on digitalis therapy.

📌 3 Key Takeaways

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Objective & Hypothesis:Here we present a case of non-occlusive mesentery ischemia induced by digitalis, which was verified angiographically.
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Key Findings & Data:Nonocclusive mesentery ischemia, a subgroup of “acute mesentery ischemia”, is known as a period of intestinal ischemic hypoperfusion without a demonstrable vascular occlusion in the mesentery bed.
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Conclusion & Impact:However, nonocclusive mesentery ischemia should be included in the differential diagnosis for patients who develop sudden and diffuse abdominal pain while on digitalis therapy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Tomografi · x-ışınlı bilgisayarlı · Anjiyografi

Abstract

Here we present a case of non-occlusive mesentery ischemia induced by digitalis, which was verified angiographically. Nonocclusive mesentery ischemia, a subgroup of “acute mesentery ischemia”, is known as a period of intestinal ischemic hypoperfusion without a demonstrable vascular occlusion in the mesentery bed. It can be caused by factors leading to splanchnic hypoperfusion, which can be of cardiac, renal or hepatic origin. In addition, it can be induced by certain drugs such as digitalis, ergotamines and vasoactive agents. In clinical practice, digitalis toxicity is commonly seen. In contrast, non-occlusive mesentery ischemia secondary to digitalis is quite rare. However, nonocclusive mesentery ischemia should be included in the differential diagnosis for patients who develop sudden and diffuse abdominal pain while on digitalis therapy.

Özet

Anjiografik olarak kanıtlanan digitalisin neden olduğu non okluziv mezenterik iskemi olgusunu sunuyoruz. Akut mezenterik iskeminin bir alt grubu olan non oklusiv mezenterik iskemi, mezenterik yatakta gösterilebilir vasküler okluzyon olmaksızın intestinal iskemik hipoperfüzyon süreci olarak bilinir. Splaknik hipoperfüzyona ilerleyen kardiyak, renal ve hepatik nedenli faktörler neden olmaktadır. İlave olarak digitalis, ergotaminler ve vasoaktif ajanlar gibi bazı ilaçlarla indüklenmektedir. Klinik pratikte digitalis toksitesi sıklıkla görülmekle birlikte digitalise ikincil non okluziv mezenterik iskemi oldukça nadirdir. Bununla birlikte, digitalis tedavisi almakta iken ani ve yaygın karın ağrısı gelişen hastaların ayırıcı tanısında non okluziv mesenterik iskemi bulunmalıdır.

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Cite This Article

KAYAHAN, H., TOPALAK, Ö., GÖKTAY, Y., SOYTÜRK, M., MERAL, M., BAŞARAN, K., DAĞLAR, Ö. (2008). Digitalisin neden olduğu, anjiografik olarak kanıtlanan non oklusiv mezenterik iskemili bir olgu. Turkish Journal of Gastroenterology, Cilt: 19 - Sayı: 2, 125–128. https://ajindex.com/articles/409909

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References (9)

  1. Trompeter M, Brazda T, Remy CT, et al. Non-occlusive mesenteric ischemia: etiology, diagnosis, and interventional therapy. Eur Radiol 2002; 12: 1179-87
  2. Lock G. Acute intestinal ischaemia. Best Pract Res Clin Gastroenterol 2001; 15: 83-98
  3. Bynum TE, Hanley HG. Effect of digitalis on estimated splanchnic blood flow. J Lab Clin Med 1982; 99: 84-91
  4. Weil J, Sen Gupta R, Herfarth H. Nonocclusive mesenteric ischemia induced by digitalis. Int J Colorectal Dis 2004; 19: 277-80
  5. Bareiss P, Desbrosses D, Christmann D, et al. Acute fatal non-occlusive intestinal ischemia during treatment with a cardiotonic glucoside. Ann Cardiol Angeiol (Paris) 1984; 33: 169-73
  6. Guglielminotti J, Tremey B, Maury E, et al. Fatal non-occlusive mesenteric infarction following digoxin intoxication. Intensive Care Med 2000; 26: 829
  7. Longhurst JC, Ross J Jr. Extracardiac and coronary vascular effects of digitalis. J Am Coll Cardiol 1985; 5: 99A-105A
  8. Brandt LJ, Boley SJ. AGA technical review on intestinal ischemia. American Gastrointestinal Association. Gastroenterology 2000; 118: 954-68
  9. Levinsky RA, Lewis RM, Bynum TE, Hanley HG. Digoxin induced intestinal vasoconstriction. The effects of proximal arterial stenosis and glucagon administration. Circulation 1975; 52: 130-6.