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Journals / Turkish Journal of Gastroenterology / 2008 / Cilt: 19 - Sayı: 4

POEMS sendromu: Olgu sunumu

POEMS syndrome: A case report

Ali ÖZDEN
Zeygam SÜLEYMAN
Gülseren SEVEN
Mutlu ARAT
Alper AKIN
Özden ŞENER
Işınsu KUZU
Kenan KEVEN
Arzu ENSARİ
Ayşe ERDEN
Ersan TAN
Pages
276–280
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We present a case differing from the other cases with her 2 g/day proteinuria and hypertrophic osteoarthropathy.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:A 43-year-old female patient admitted with a 2.5-year history of lower extremity symmetrical sensorimotor polyneuropathy, hypertrichosis, sweating, diarrhea, weight loss, and hyperpigmentation.
📊
Key Findings & Data:The clinical evaluation met the criteria for the diagnosis of POEMS syndrome.
💡
Conclusion & Impact:We present a case differing from the other cases with her 2 g/day proteinuria and hypertrophic osteoarthropathy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Siklofosfamid · İlaç tedavisi · kombinasyon

Abstract

A 43-year-old female patient admitted with a 2.5-year history of lower extremity symmetrical sensorimotor polyneuropathy, hypertrichosis, sweating, diarrhea, weight loss, and hyperpigmentation. The clinical evaluation met the criteria for the diagnosis of POEMS syndrome. The patient was initially treated with prednisolone and responded well. We planned high-dose chemotherapy with autologous stem cell rescue and introduced a more immunosuppressive regimen containing cyclophosphamide and dexamethasone. We present a case differing from the other cases with her 2 g/day proteinuria and hypertrophic osteoarthropathy.

Özet

43 yaşındaki kadın hasta 2,5 yıldır devam eden alt ekstremitelerde simetrik sensorimotor polinöropati, hipertrikozis, terleme, ishal, kilo kaybı ve pigmentasyon artışı ile servisimize kabul edildi. Klinik değerlendirmede bulgular POEMS Sendromu’nun tanı kriterleri ile uyumluydu. Hasta başlangıçta prednizolon ile tedavi edildi ve iyi yanıt alındı. Biz otolog yüksek doz kemoterapi sonrası otolog kök hücre nakli planladık. Burada 2 gram/gün proteinürisi ve hipertrofik osteoartropatisi ile diğer olgulardan farklı bir olgu sunduk.

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Cite This Article

ÖZDEN, A., SÜLEYMAN, Z., SEVEN, G., ARAT, M., AKIN, A., ŞENER, Ö., KUZU, I., KEVEN, K., ENSARİ, A., ERDEN, A., TAN, E. (2008). POEMS sendromu: Olgu sunumu. Turkish Journal of Gastroenterology, Cilt: 19 - Sayı: 4, 276–280. https://ajindex.com/articles/409908

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