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Journals / Turkish Journal of Gastroenterology / 2019 / Cilt: 30 - Sayı: 3

Adverse factors responsible for below-normal platelet count after laparoscopic splenectomy and azygoportal disconnection

Dou-Sheng BAI
Wen-Yu SHAO
Chi ZHANG
Ping CHEN
Sheng-Jie JİN
Guo-Qing JIANG
Pages
254–259
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

This study aimed toevaluate the adverse factors responsible for platelet (PLT) counts below the normal lower limit following laparoscopic splenectomy andazygoportal disconnection (LSD).Materials and Methods: We retrospectively evaluated the outcomes of 123 cirrhotic patients with portal hypertensive bleeding andsecondary hypersplenism, who underwent LSD and who had PLT counts 50 years and longitudinal spleen diameter ≤160 mm were threshold values for an increased risk of the PLT count <125×109/L at POM 3 after LSD.Conclusion: Age was an independent positive predictor and longitudinal spleen diameter an independent negative predictor of PLTcount <125×109/L at POM 3 after LSD.

📌 3 Key Takeaways

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Objective & Hypothesis:Background/Aims: Splenectomy is regarded as an effective curative treatment for thrombocytopenia caused by hypersplenism in patients with cirrhosis.
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Key Findings & Data:However, in clinical practice, thrombocytopenia is not resolved by splenectomy in all patients.
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Conclusion & Impact:This study aimed toevaluate the adverse factors responsible for platelet (PLT) counts below the normal lower limit following laparoscopic splenectomy andazygoportal disconnection (LSD).Materials and Methods: We retrospectively evaluated the outcomes of 123 cirrhotic patients with portal hypertensive bleeding andsecondary hypersplenism, who underwent LSD and who had PLT counts 50 years and longitudinal spleen diameter ≤160 mm were threshold values for an increased risk of the PLT count <125×109/L at POM 3 after LSD.Conclusion: Age was an independent positive predictor and longitudinal spleen diameter an independent negative predictor of PLTcount <125×109/L at POM 3 after LSD.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Background/Aims: Splenectomy is regarded as an effective curative treatment for thrombocytopenia caused by hypersplenism in patients with cirrhosis. However, in clinical practice, thrombocytopenia is not resolved by splenectomy in all patients. This study aimed toevaluate the adverse factors responsible for platelet (PLT) counts below the normal lower limit following laparoscopic splenectomy andazygoportal disconnection (LSD).Materials and Methods: We retrospectively evaluated the outcomes of 123 cirrhotic patients with portal hypertensive bleeding andsecondary hypersplenism, who underwent LSD and who had PLT counts 50 years and longitudinal spleen diameter ≤160 mm were threshold values for an increased risk of the PLT count <125×109/L at POM 3 after LSD.Conclusion: Age was an independent positive predictor and longitudinal spleen diameter an independent negative predictor of PLTcount <125×109/L at POM 3 after LSD.

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Cite This Article

BAI, D., SHAO, W., ZHANG, C., CHEN, P., JİN, S., JIANG, G. (2019). Adverse factors responsible for below-normal platelet count after laparoscopic splenectomy and azygoportal disconnection. Turkish Journal of Gastroenterology, Cilt: 30 - Sayı: 3, 254–259. https://ajindex.com/articles/408740

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References (14)

  1. Ikegami T, Shimada M, Imura S. Recent role of splenectomy in chronic hepatic disorders. Hepatol Res 2008
  2. [CrossRef] Imura S, Shimada M, Utsunomiya T, et al. Impact of splenectomy in patients with liver cirrhosis: results from 18 patients in a single center experience. Hepatol Res 2010
  3. [CrossRef] Tomikawa M, Hashizume M, Akahoshi T, et al. Effects of splenectomy on liver volume and prognosis of cirrhosis in patients with esophageal varices. J Gastroenterol Hepatol 2002
  4. [CrossRef] Ushitora Y, Tashiro H, Takahashi S, et al. Splenectomy in chronic hepatic disorders: portal vein thrombosis and improvement of liver function. Digest Surg 2011
  5. [CrossRef] Shimada M, Hashizume M, Shirabe K, Takenaka K Sugimachi K. A new surgical strategy for cirrhotic patients with hepatocellular carcinoma and hypersplenism. Performing a hepatectomy after a laparoscopic splenectomy. Surg Endosc 2000
  6. [CrossRef] Bao H, He Q, Dai N, Ye R, Zhang Q. Retrospective Study to Compare Selective Decongestive Devascularization and Gastrosplenic Shunt versus Splenectomy with Pericardial Devascularization for the Treatment of Patients with Esophagogastric Varices Due to Cirrhotic Portal Hypertension. Med Sci Monit 2017
  7. [CrossRef] Qian YY, Li K. The early prevention and treatment of PVST after laparoscopic splenectomy: A prospective cohort study of 130 patients. Int J Surg 2017
  8. [CrossRef] Su AP, Zhang ZD, Tian BL, Zhu JQ. Transjugular intrahepatic portosystemic shunt versus open splenectomy and esophagogastric devascularization for portal hypertension with recurrent variceal bleeding. Hepatobiliary Pancreat Dis Int 2017
  9. [CrossRef] Jiang Y, Ying X, Kane S, Mukhopadhyay M, Qian X. Violence against doctors in China. Lancet 2014
  10. [CrossRef] Bawaskar HS. Violence against doctors in India. Lancet 2014
  11. [CrossRef] Bai DS, Qian JJ, Chen P, et al. Modified laparoscopic and open splenectomy and azygoportal disconnection for portal hypertension. Surg Endosc 2014
  12. [CrossRef] Jiang G, Qian J, Yao J, Wang X, Jin S, Bai D. A New Technique for Laparoscopic Splenectomy and Azygoportal Disconnection. Surg Innov 2014
  13. [CrossRef] Vázquez-Santiago M, Ziyatdinov A, Pujol-Moix N, et al. Age and gender effects on 15 platelet phenotypes in a Spanish population. Comput Biol Med 2016
  14. [CrossRef] Biino G, Santimone I, Minelli C, et al. Age- and sex-related variat