SavedAdd your journal

Journals / Turkish Journal of Gastroenterology / 2020 / Cilt: 31 - Sayı: 7

Vagus nerve assessment via ultrasonography in irritable bowel syndrome. Are there any changes of dimension in the vagus nerve?

Ömer ÖZÇAĞALAYAN
Tuğba İlkem KURTOĞLU ÖZÇAĞALAYAN
Mücahit DOĞRU
Rafet METE
Pages
503–507
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This might show that VN is only a transporter of abnormal neuronal stimulations according to IBS pathophysiology.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background/Aims: Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder which has a close relationship with the central nervous system (CNS).
📊
Key Findings & Data:This study aimed to investigate the possible changes of the dimension of VN with vagus ultrasonography (VU) in IBS.Materials and Methods: A total of 119 patients consisting of 66 IBS patients appropriated with Rome IV criteria and 53 patients of the control group were enrolled in the study.
💡
Conclusion & Impact:This might show that VN is only a transporter of abnormal neuronal stimulations according to IBS pathophysiology.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Background/Aims: Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder which has a close relationship with the central nervous system (CNS). Vagus nerve (VN) is the major connector between CNS and the enteric nervous system (ENS). This study aimed to investigate the possible changes of the dimension of VN with vagus ultrasonography (VU) in IBS.Materials and Methods: A total of 119 patients consisting of 66 IBS patients appropriated with Rome IV criteria and 53 patients of the control group were enrolled in the study. All patients underwent colonoscopy to rule out organic pathologies, such as polyposis, inflammatory bowel syndromes, diverticulosis, and colon cancer. Right vagus (RV) and left vagus(LV) nerve areas and diameters were calculated with VU.Results: There was no statistical difference in the RV (p=0.445) and LV (p=0.944) diameters between the two groups. In addition, there was no statistical difference in RV (p=0.549) and LV (p=0.874) areas between the IBS and control groups.Conclusion: VU clearly depicted that there are no changes of dimension in VN areas and diameters in IBS. This might show that VN is only a transporter of abnormal neuronal stimulations according to IBS pathophysiology.

🔖

Cite This Article

ÖZÇAĞALAYAN, Ö., ÖZÇAĞALAYAN, T. İ. K., DOĞRU, M., METE, R. (2020). Vagus nerve assessment via ultrasonography in irritable bowel syndrome. Are there any changes of dimension in the vagus nerve?. Turkish Journal of Gastroenterology, Cilt: 31 - Sayı: 7, 503–507. https://ajindex.com/articles/408678

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (1)

  1. Drossman DA. The functional gastrointestinal disorders and the Rome III process. Gas-troenterology 2006; 130: 1377-90. [Crossref] 2. Coss-Adame E, Rao SS. Brain and gut interactions in irritable bowel syndrome: new paradigms and new understandings. Curr Gastroenterol Rep 2014; 16: 379. [Crossref] 3. Bonaz B, Sinniger V, Pellissier S. The vagus nerve in the neuro-immune axis: implications in the pathology of the gastrointestinal tract. Front Immunol 2017; 8: 1452. [Crossref] 4. Mayer EA, Naliboff BD, Chang L, Coutinho SV. V. Stress and irritable bowel syndrome. Am J Physiol Gastrointest Liver Physiol 2001; 280: G519-24. [Crossref] 5. Mulak A, Bonaz B. Irritable bowel syndrome: a model of the braingut interactions. Med Sci Monit 2004; 10: RA55-62. 6. Holtmann G, Shah A, Morrison M. Pathophysiology of functional gastrointestinal disorders: a holistic overview. DigDis 2017; 35: 5-13. [Crossref] 7. Mayer EA, Naliboff BD, Chang L. Basic pathophysiologic mechanisms in irritable bowel syndrome. Dig Dis 2001; 19: 212-8. [Crossref] 8. Pellissier S, Dantzer C, Mondillon L, et al. Relationship between vagal tone, cortisol, TNF-alpha, epinephrine and negative affects in Crohn’s disease and irritable bowel syndrome. PLoS One 2014; 9: e105328. [Crossref] 9. Knappertz VA, Tegeler CH, Hardin SJ, McKinney WM. Vagus nerve imaging with ultrasound: anatomic and in vivo validation. Otolaryngol Head Neck Surg 1998; 118: 82-5. [Crossref] 10. Canavan C, West J, Card T. The epidemiology of irritable bowel syndrome. Clin Epidemiol 2014; 6: 71-80. [Crossref] 11. Camilleri M. Pathophysiology in irritable bowel syndrome. Drug News Perspect 2001; 14: 268-78. [Crossref] 12. Buckley MM, O’Mahony SM, O’Malley D. Convergence of neuro-endocrine-immune pathways in the pathophysiology of irritable bowel syndrome. World J Gastroenterol 2014; 20: 8846-58. 13. Lydiard RB. Irritable bowel syndrome, anxiety, and depression: what are the links? J Clin Psychiatry 2001; 62 Suppl 8: 38-45; discussion 46-7. 14. Bonaz B, Bazin T, Pellissier S. The vagus nerve at the interface of the microbiota-gut-brain axis. Front Neurosci 2018; 12: 49. [Crossref] 15. Lee CT, Chuang TY, Lu CL, et al. Abnormal vagal cholinergic function and psychological behaviors in irritable bowel syndrome patients: a hospital-based Oriental study. Dig Dis Sci 1998; 43: 1794-9. [Crossref] 16. Carabotti M, Scirocco A, Maselli MA, Severi C. The gut-brain axis: interactions between enteric microbiota, central and enteric nervous system