Journals / Çocuk Acil ve Yoğun Bakım Dergisi / 2021 / Cilt: 8 - Sayı: 3

Meningocoxemic Septic Shock; A Case Report and Review of the Literature

Meningokoksemik Septik Şok; Olgu Sunumu ve Literatürün Gözden Geçirilmesi

Pages
133–139
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This case report includes a review of septic shock therapy due to meningococemia in a patient who was diagnosed with invasive meningococcal disease and died despite rapid and appropriate treatment methods.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Meningococcal infections that have high mortality and morbidity in childhood and progress rapidly are an important health problem.
📊
Key Findings & Data:Neisseria meningitidis has 13 serogroups.
💡
Conclusion & Impact:This case report includes a review of septic shock therapy due to meningococemia in a patient who was diagnosed with invasive meningococcal disease and died despite rapid and appropriate treatment methods.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Meningococcal infections that have high mortality and morbidity in childhood and progress rapidly are an important health problem. It is one of the most important emergent diseases of the infectious diseases. Neisseria meningitidis has 13 serogroups. A, B, C, Y and W135 are the most common cause of invasive diseases among these serogroups. The outcome of meningococcal disease is dependent on the immediate recognition of two major complications: Shock and increased intracranial pressure syndrome. Rapid recognition of the disease and these complications are very important for the outcome of affected patients with appropriate treatment. Our case is a 6-month-old girl who presented with fever, malaise and a rapidly spreading rash all over the body. Septic shock due to meningocoxemia was considered because of the typical rash, weakness, susceptibility to sleep and low blood pressure. This case report includes a review of septic shock therapy due to meningococemia in a patient who was diagnosed with invasive meningococcal disease and died despite rapid and appropriate treatment methods.

Özet

Çocukluk çağında yüksek mortalite ve morbiditeye sahip olan, oldukça hızlı ilerleyen meningokok enfeksiyonları önemli bir sağlık sorunudur. Enfeksiyon hastalıklarının en önemli acil hastalığıdır. Neisseria meningitidis’in 13 serogrubu vardır. A, B, C, Y ve W135 en fazla invaziv hastalık yapan serogruplardır. Meningokok hastalığının sonucu, kritik olarak iki önemli komplikasyonun derhal tanınmasına bağlıdır: Şok ve kafa içi basınç artış sendromu. Hastalığın ve bu komplikasyonların hızlı tanınarak uygun tedavisi, etkilenen hastaların sonucu için çok önemlidir. Olgumuz ateş, halsizlik ve tüm vücuda hızla yayılan döküntü nedeniyle başvuran 6 aylık kız hastadır. Hastada; tipik döküntü, halsizlik, uykuya eğilimli olması ve tansiyon düşüklüğü nedeniyle meningokoksemiye bağlı septik şok düşünülmüştür. Bu olgu raporu, invaziv meningokok hastalığı tanısıyla yatan, hızlı ve uygun tedavi yöntemleri uygulanmasına rağmen kaybedilen bir hasta üzerinden meningokoksemiye bağlı septik şok tedavisinin gözden geçirilmesini içermektedir

🔖

Cite This Article

ÖZKALE, M., GÖKAY, N., YILDIZTAŞ, D. (2021). Meningocoxemic Septic Shock; A Case Report and Review of the Literature. Çocuk Acil ve Yoğun Bakım Dergisi, Cilt: 8 - Sayı: 3, 133–139. https://ajindex.com/articles/406917

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (9)

  1. Kaplan SL, Schutze GE, Leake JA, Barson WJ, Halasa NB, et al. Multicenter surveillance of invasive meningococcal infections in children. Pediatrics. 2006;118:e979-84. Kendirli T, Yıldızdaş D, Boşnak M, Köroglu T, Duman M, ve ark. Çocuk Yoğun Bakım Ünitelerinde Meningokoksemi: Demografik, Epidemiyolojik ve Klinik Özellikler. J Pediatr Emerg Intens Care Med. 2015;2:7-12. Hazelzet JA. Diagnosing meningococcemia as a cause of sepsis. Pediatr Crit Care Med. 2005;6(3 Suppl):S50-4. Rosenstein NE, Perkins BA, Stephens DS, Popovic T, Hughes JM. Meningococcal disease. N Engl J Med. 2001;344:1378-88.
  2. Theilen U, Wilson L, Wilson G, Beattie JO, Qureshi S, et al. Management of invasive meningococcal disease in children and young people: summary of SIGN guidelines. BMJ. 2008;336:1367- 70. Maat M, Buysse CM, Emonts M, Spanjaard L, Joosten KF, et al. Improved survival of children with sepsis and purpura: effects of age, gender, and era. Crit Care. 2007;11:R112. Tzeng YL, Stephens DS. Epidemiology and pathogenesis of Neisseria meningitidis. Microbes Infect. 2000;2:687-700.
  3. Kepenekli E, Tuygun N, Tanır G. Çocuklarda invazif Meningokokkal Hastalık 7 Hastada Klinik Özellikler ve Tedavi Yaklaşımının Değerlendirilmesi. J Pediatr Inf. 2008;2:152-5.
  4. Beran O, Lawrence DA, Andersen N, Dzupova O, Kalmusova J, et al. Sequential analysis of biomarkers in cerebrospinal fluid and serum during invasive meningococcal disease. Eur J Clin Microbiol Infect Dis. 2009;28:793-9.
  5. Alhan E, Bozdemir N, Yüksel B, Onenli N, Kocabaş E, ve ark. Epidemiology of meningococcal infections in children in midsouthern part of Turkey. Eur J Epidemiol. 1995;11:393-6.
  6. Malley R, Huskins WC, Kuppermann N. Multivariable predictive models for adverse outcome of invasive meningococcal disease in children. J Pediatr. 1996;129:702-10.
  7. Thompson MJ, Ninis N, Perera R, Mayon-White R, Phillips C, et al. Clinical recognition of meningococcal disease in children and adolescents. Lancet. 2006;367:397-403.
  8. Wang X, Theodore MJ, Mair R, Trujillo-Lopez E, du Plessis M, et al. Clinical validation of multiplex real-time PCR assays for detection of bacterial meningitis pathogens. J Clin Microbiol. 2012;50:702-8.
  9. Tolaj I, Ramadani H, Mehmeti M, Gashi H, Kasumi A, et al. Does Dexamethasone Helps in Meningococcal Sepsis? Med Arch. 2017;71:173-7. van de Beek D, Farrar JJ, de Gans J, Mai NT, Molyneux EM, et al. Adjunctive dexamethasone in bacterial meningitis: a meta-analysis of individual patient data. Lancet Neurol. 2010;9:254-63. Har