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Journals / BEYOGLU EYE JOURNAL / 2021 / Cilt: 6 - Sayı: 4

Evaluation of Peripapillary Microcirculation in Patients with Acromegaly

Mine KARAHAN
Atılım Armağan DEMİRTAŞ
Leyla HAZAR
Sedat AVA
Zafer PEKKOLAY
Uğur KEKLİKÇİ
Pages
285–289
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This method of non-invasive quantitative analysis of retinal perfusion using OCTA may be useful for future studies involving patients with acromegaly.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: The aim of this study was to evaluate the radial peripapillary capillary (RPC) and the optic nerve head (ONH) perfusion of patients with acromegaly using optical coherence tomography angiography (OCTA).
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Key Findings & Data:Methods: Twenty-four eyes of 24 acromegaly patients comprised the study group and 24 eyes of 24 healthy individuals were used as a control group.
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Conclusion & Impact:This method of non-invasive quantitative analysis of retinal perfusion using OCTA may be useful for future studies involving patients with acromegaly.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Objectives: The aim of this study was to evaluate the radial peripapillary capillary (RPC) and the optic nerve head (ONH) perfusion of patients with acromegaly using optical coherence tomography angiography (OCTA). Methods: Twenty-four eyes of 24 acromegaly patients comprised the study group and 24 eyes of 24 healthy individuals were used as a control group. The ONH and RPC vascular density (VD) was measured for each patient using OCTA. The insulin-like growth factor 1 (IGF-1) levels were also recorded and compared. Results: The VD of the inferior nasal ONH and nasal RPC was significantly lower in the acromegaly group than in the control group (p=0.047 and p=0.001, respectively). There was a significant negative correlation between the VD of the superior nasal ONH and the IGF-1 level (r=-0.283, p=0.038). Conclusion: The ONH and RPC VD values measured using OCTA were segmentally different in the acromegaly group compared with those of the control group. This method of non-invasive quantitative analysis of retinal perfusion using OCTA may be useful for future studies involving patients with acromegaly.

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Cite This Article

KARAHAN, M., DEMİRTAŞ, A. A., HAZAR, L., AVA, S., PEKKOLAY, Z., KEKLİKÇİ, U. (2021). Evaluation of Peripapillary Microcirculation in Patients with Acromegaly. BEYOGLU EYE JOURNAL, Cilt: 6 - Sayı: 4, 285–289. https://ajindex.com/articles/406552

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