AI Summary & Key Takeaways
AI InsightDecompression surgery canproduce favorable diffusional alterations.
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Özet
AIM: To evaluate the preoperative and postoperative 6th month mean apparent diffusion coefficient (ADC) values of the cerebellartonsils and bulbus in patients with Chiari Malformation Type I (CMI), and to compare the results with healthy controls.MATERIAL and METHODS: We included 15 patients with CMI who underwent suboccipital decompression, upper cervicallaminectomy, and duraplasty surgery, and compared them with 10 healthy individuals. Three regions of interest were placed, oneeach in the cerebellar tonsils and one in the bulbus. The mean ADC values were measured separately in each region.RESULTS: Among the patients, mean ADC values were significantly decreased after surgery compared with before surgery. Themean ADC values before surgery were significantly higher for patients than for controls; however, although the mean ADC valueswere slightly higher after surgery for patients than for controls, the differences were not significant. Thus, after surgical intervention,ADC values in patients with CMI became close to those of normal individuals.CONCLUSION: The increased ADC values in patients with CMI before surgery implied that not only morphologic changes but alsoincreased diffusivity may play a key role in the pathophysiology and clinical presentation of the disease. Decompression surgery canproduce favorable diffusional alterations.