Journals / Turkish Neurosurgery / 2017 / Cilt: 27 - Sayı: 3

The Relationship of Hematoma Growth to Red Blood Cell Distribution Width in Patients with Hypertensive Intracerebral Hemorrhage

Pages
368–373
DOI
—
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⚡ TL;DR(Too Long; Didn't Read)

Additionally, this study demonstrated that these parameters are easily obtainable and could be used to effectively evaluate outcomes in ICH patients.

📌 3 Key Takeaways

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Objective & Hypothesis:AIm: Hypertension is a primary risk factor for intracerebral hemorrhage (ICH) and is thought to be responsible for about 55% of all ICH cases.
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Key Findings & Data:Thus, the primary goal of the study was to examine whether the status of vascular rheological factors upon admission to the hospital was associated with hypertensive ICH growth and early outcomes. mATERIAl and mEThODS: Over a 2-year period, the present study evaluated 60 ICH patients who were admitted within the first 12 hours of symptom onset.
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Conclusion & Impact:Additionally, this study demonstrated that these parameters are easily obtainable and could be used to effectively evaluate outcomes in ICH patients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

AIm: Hypertension is a primary risk factor for intracerebral hemorrhage (ICH) and is thought to be responsible for about 55% of all ICH cases. Thus, the primary goal of the study was to examine whether the status of vascular rheological factors upon admission to the hospital was associated with hypertensive ICH growth and early outcomes. mATERIAl and mEThODS: Over a 2-year period, the present study evaluated 60 ICH patients who were admitted within the first 12 hours of symptom onset. Brain computed tomography scans were performed at admission and then 24 hours later as a control. Hematoma growth was classified as an volume increase more than 6.5 ml or >33%, and good outcome was defined using the modified Rankin Scale (mRS) score (<= 2 at 3 months). RESUlTS: The mean age of the study population was 65.07 ± 11.659 years, with 34 men and 26 women. The leading vascular risk factor was hypertension (86.7%). There were significant associations between the initial red blood cell distribution width (RDW) and hematoma growth (p=0.038). Therefore, hematoma growth in the first 24 hours after symptom onset was significantly related to a poor clinical outcome at 3 months (p = 0.050). CONClUSION: The study identified significant relationships between the initial RDW and poor outcome as well as the initial RDW and hypertensive hematoma growth. Additionally, this study demonstrated that these parameters are easily obtainable and could be used to effectively evaluate outcomes in ICH patients.

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Cite This Article

ALTINTAŞ, Ö., DÜRÜYEN, H., BARAN, G., BARAN, O., KATAR, S., ANTAR, V., ASİL, T. (2017). The Relationship of Hematoma Growth to Red Blood Cell Distribution Width in Patients with Hypertensive Intracerebral Hemorrhage. Turkish Neurosurgery, Cilt: 27 - Sayı: 3, 368–373. https://ajindex.com/articles/404557

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References (1)

  1. Ani C, Ovbiagele B: Elevated red blood cell distribution width predicts mortality in persons with known stroke. J Neurol Sci 277: 103-108, 2009 2. Broderick JP, Diringer MN, Hill MD, Brun NC, Mayer SA, Steiner T, Skolnick BE, Davis SM: Determinants of intracerebral hemorrhage growth: An exploratory analysis. Stroke 38: 1072- 1075, 2007 3. Chakrabarty A, Shivane A: Pathology of intracerebral hemorrhage. ACNR 8(1): 20-21, 2008 4. Demchuk AM, Dowlatshahi D, Rodriguez-Luna D, Molina CA, Blas YS, Dzialowski I, Kobayashi A, Boulanger JM, Lum C, Gubitz G, Padma V, Roy J, Kase CS, Kosior J, Bhatia R, Tymchuk S, Subramaniam S, Gladstone DJ, Hill MD, Aviv RI, PREDICT/Sunnybrooke ICH CTA study group: Prediction of hematoma growth and outcome in patients with intracerebral hemorrhage using the CT-angiography spot sign (PREDICT): A prospective observational study. Lancet Neurol 11: 307-314, 2012 5. Fatemi O, Torguson R, Chen F, Ahmad S, Badr S, Satler LF, Pichard AD, Kleiman NS, Waksman R: Red cell distribution width as a bleeding predictor after percutaneous coronary intervention. Am Heart J 166: 104-109, 2013 6. Fukuta H, Ohte N, Mukai S, Saeki T, Asada K, Wakami K, Kimura G: Elevated plasma levels of B-type natriuretic peptide but not C-reactive protein are associated with higher red cell distribution width in patients with coronary artery disease. Int Heart J 50: 301-312, 2009 7. Garcia JH, Ho KL, Caccamo DV: Intracerebral hemorrhage: Pathology of selected topics. In: Kase CS, Caplan LR (eds), Intracerebral Hemorrhage. Boston: Butterworth-Heinemann, 1994: 45-50 8. Gonçalves S, Ferreira Santos J, Amador P, Rassi L, Rodrigues AR, Seixo F, Neves Soares L: Impact of red blood cell distribution width on risk for bleeding events in patients with non-ST elevation acute coronary syndromes. Rev Port Cardiol 32: 27-33, 2013 9. Howard G, Cushman M, Howard VJ, Kissela BM, Kleindolfer DO, Moy CS, Switzer J, Woo D: Risk factors for intracerebral hemorrhage. The reasons for geographic and racial differences in stroke (REGARDS) study. Stroke 44:1282-1287, 2013 10. Kase CS, Mohr JP, Caplan LR: Intracerebral hemorrhage. In: Mohr JP, Wolf PA, Grotta JC, Moskowitz MA, Mayberg MR, von Kummer R (eds), Stroke. Elsevier, 2011: 327-376 11. Kothari RU, Brott T, Broderick JP, Barsan WG, Sauerbeck LR, Zuccarello M, Khoury J: The ABCs of measuring intracerebral hemorrhage volumes. Stroke 27:1304, 1996 12. Morgenstern LB, Hemphill JC 3rd, Anderson C, Becker K, Broderick JP, Connolly ES Jr, G