Journals / Turkish Neurosurgery / 2020 / Cilt: 30 - Sayı: 3

ABO and Rh Blood Groups and Risk of Myelomeningocele

Pages
449–453
DOI
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Rh-positive blood group wasassociated with high incidence of myelomeningocele (93.5%), whereas Rh-negative blood group showed least association (6.5%).Rh-positive blood group was also found to be more frequent in patients with myelomeningocele with hydrocephalus and Chiarimalformation.CONCLUSION: The findings of this study show that ABO and Rh blood groups have an effect on the development of myelomeningoceleunder the influence of environmental or genetic factors.

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Objective & Hypothesis:AIM: To investigate the relationship between the distribution of ABO or Rhesus (Rh) blood group antigens and the incidence ofmyelomeningocele.MATERIAL and METHODS: A retrospective data was reviewed for all myelomeningocele patients operated at a tertiary academichospital between years 2014 and 2019.
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Key Findings & Data:Age, sex, delivery method, physical and neurological examination findings, and radiologicalfindings alongside with blood type of each patient were recorded.
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Conclusion & Impact:Rh-positive blood group wasassociated with high incidence of myelomeningocele (93.5%), whereas Rh-negative blood group showed least association (6.5%).Rh-positive blood group was also found to be more frequent in patients with myelomeningocele with hydrocephalus and Chiarimalformation.CONCLUSION: The findings of this study show that ABO and Rh blood groups have an effect on the development of myelomeningoceleunder the influence of environmental or genetic factors.
🔬Design:Review & Systematic Survey
📍Scope:2014 Verileri
⚙️Variables:Domain Parameters

Özet

AIM: To investigate the relationship between the distribution of ABO or Rhesus (Rh) blood group antigens and the incidence ofmyelomeningocele.MATERIAL and METHODS: A retrospective data was reviewed for all myelomeningocele patients operated at a tertiary academichospital between years 2014 and 2019. Age, sex, delivery method, physical and neurological examination findings, and radiologicalfindings alongside with blood type of each patient were recorded. The data of blood group distribution among the study patientswas compared to the data of healthy individuals in the same region.RESULTS: Patients with group B and AB showed a higher chance of developing myelomeningocele. Rh-positive blood group wasassociated with high incidence of myelomeningocele (93.5%), whereas Rh-negative blood group showed least association (6.5%).Rh-positive blood group was also found to be more frequent in patients with myelomeningocele with hydrocephalus and Chiarimalformation.CONCLUSION: The findings of this study show that ABO and Rh blood groups have an effect on the development of myelomeningoceleunder the influence of environmental or genetic factors.

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Cite This Article

IŞIK, S., ÇEVİK, S., TURHAN, A. H., BAYGÜL, A., HANIMOĞLU, H. (2020). ABO and Rh Blood Groups and Risk of Myelomeningocele. Turkish Neurosurgery, Cilt: 30 - Sayı: 3, 449–453. https://ajindex.com/articles/404342

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References (1)

  1. Allouh MZ, Al Barbarawi MM, Hiasat MY, Al-Qaralleh MA, Ababneh EI: Glioblastoma and ABO blood groups: further evidence of an association between the distribution of blood group antigens and brain tumours. Blood Transfus 15(6):543- 547, 2017 2. Avent ND, Reid ME: The Rh blood group system: A review. Blood 95(2):375-387, 2000 3. Beaudin AE, Stover PJ: Insights into metabolic mechanisms underlying folate-responsive neural tube defects: A minireview. Birth Defects Res A Clin Mol Teratol 85:274–284, 2009 4. Blom HJ, Shaw GM, den Heijer M, Finnell RH: Neural tube defects and folate: Case far from closed. Nat Rev Neurosci 7: 724-731, 2006 5. Copp AJ, Greene ND: Neural tube defects: Prevention by folic acid and other vitamins. Indian J Pediatr 67:915-921, 2000 6. Cildag S, Kara Y, Senturk T: ABO blood groups and rheumatic diseases. Eur J Rheumatol 4:250-253, 2017 7. De Marco P, Merello E, Mascelli S, Capra V: Current perspectives on the genetic causes of neural tube defects. Neurogenetics 7:201-221, 2006 8. Detrait ER, George TM, Etchevers HC, Gilbert JR, Vekemans M, Speer MC: Human neural tube defects: Developmental biology, epidemiology, and genetics. Neurotox Teratol 27:515- 524, 2005 9. Donbak L, Rencuzogullari E, Topaktas M, Kayrın L: Detection of some blood group (ABO, RH-D) and serum protein (HP, a1- AT, TF) polymor-phisms in Antakya Province, Turkey. T Klin J Med Res 20:109-113, 2002 10. Enaw JO, Zhu H, Yang W, Lu W, Shaw GM, Lammer EJ, Finnell RH: CHKA and PCYT1A gene polymorphisms, choline intake and spina bifida risk in a California population. BMC Med 4: 36, 2006 11. Fatic N, Lukac H, Radojevic N, Simanic I, Banzic I, Pajovic BO: Blood group as an indicator for abdominal aortic aneurysm. Eur Rev Med Pharmacol Sci 19:2997-3000, 2015 12. Franchini M, Liumbruno GM: ABO blood group and neurodegenerative disorders: More than a casual association. Blood Transfus 14(2):158-159, 2016 13. Franchini M, Liumbruno GM, Lippi G: The prognostic value of ABO blood group in cancer patients. Blood Transfus 6:1-7, 2015 14. Franke B, Vermeulen SH, Steegers-Theunissen RP, Coenen MJ, Schijvenaars MM, Scheffer H, den Heijer M, Blom HJ: An association study of 45 folate-related genes in spina bifida: Involvement of cubilin (CUBN) and tRNA aspartic acid methyltransferase 1 (TRDMT1). Birth Defects Res A Clin Mol Teratol 85(3):216-226, 2009 15. Green T, Chen X, Ryan S, Asch AS, Ruiz-Echevarría MJ: TMEFF2 and SARDH cooperate to modulate one-carbon metabolism and invasion of pr