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Journals / Turkish Journal of Pharmaceutical Sciences / 2016 / Cilt: 13 - Sayı: 1

Türkiye'de Yetişen Üç Alnus Taksonunun Metanollü Ekstrelerinde Şikimik Asit Miktar Tayini

Quantification of Shikimic Acid in the Methanolic Extracts of Three Alnus Taxons Growing in Turkey

Çiğdem ALTINYAY
Burçin ERGENE ÖZ
MEHMET LEVENT ALTUN
Pages
115–120
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The quantitative analysis of methanol extracts prepared from the leaves of A. glutinosa subsp. glutinosa, A. orientalis var. orientalis and A. orientalis var. pubescens revealed that shikimic acid amount was found to be 0.6491%, 0.4309% and 0.2452% respectively.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Shikimic acid is a phenolic acid which is known to possess several activities and it takes attention as a leading compound to some synthetic medicinal substances as well.
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Key Findings & Data:In this study, high performance liquid chromatographic analyses were carried out in order to determine shikimic acid contents of Alnus glutinosa subsp. glutinosa, A. orientalis var. orientalis and A. orientalis var. pubescens; acetonitrile and 0.2% o-phosphoric acid:water mixture with isocratic flow was used as mobile phase.
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Conclusion & Impact:The quantitative analysis of methanol extracts prepared from the leaves of A. glutinosa subsp. glutinosa, A. orientalis var. orientalis and A. orientalis var. pubescens revealed that shikimic acid amount was found to be 0.6491%, 0.4309% and 0.2452% respectively.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Shikimic acid is a phenolic acid which is known to possess several activities and it takes attention as a leading compound to some synthetic medicinal substances as well. In this study, high performance liquid chromatographic analyses were carried out in order to determine shikimic acid contents of Alnus glutinosa subsp. glutinosa, A. orientalis var. orientalis and A. orientalis var. pubescens; acetonitrile and 0.2% o-phosphoric acid:water mixture with isocratic flow was used as mobile phase. The flow rate was 0.5 ml/min. The quantitative analysis of methanol extracts prepared from the leaves of A. glutinosa subsp. glutinosa, A. orientalis var. orientalis and A. orientalis var. pubescens revealed that shikimic acid amount was found to be 0.6491%, 0.4309% and 0.2452% respectively.

Özet

Şikimik asit, çeşitli biyolojik aktivitelere sahip ve aynı zamanda, bazı sentetik maddeler için başlangıç materyali olarak dikkat çeken bir fenolik asittir. Bu çalışmada, Alnus glutinosa subsp. glutinosa, A. orientalis var. orientalis ve A. orientalis var. pubescens ile yüksek performanslı sıvı kromatografisi analizleri yapılmış; asetonitril ve %0.2 o-fosforik asit:su karışımı izokratik akış ile mobil faz olarak kullanılmıştır. Akış hızı 0.5 ml/dk olarak verilmiştir. A. glutinosa subsp. glutinosa, A. orientalis var. orientalis ve A. orientalis var. pubescens yapraklarından hazırlanan metanol ekstrelerinde şikimik asit miktarları sırasıyla, %0.6491, %0.4309 ve %0.2452 olarak tespit edilmiştir.

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Cite This Article

ALTINYAY, Ç., ÖZ, B. E., ALTUN, M. L. (2016). Türkiye'de Yetişen Üç Alnus Taksonunun Metanollü Ekstrelerinde Şikimik Asit Miktar Tayini. Turkish Journal of Pharmaceutical Sciences, Cilt: 13 - Sayı: 1, 115–120. https://ajindex.com/articles/404143

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