Journals / Turkish Journal of Pharmaceutical Sciences / 2013 / Cilt: 10 - Sayı: 2

Anchusa azurea var. azured'xvm köklerinden elde edilen fenolik bileşikler

Phenolic compounds from the roots of Anchusa azurea var. azurea

Pages
177–184
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This is the first report on the isolation of phenolic compounds from the roots of A. azurea.

📌 3 Key Takeaways

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Objective & Hypothesis:In Turkish folk medicine, Anchusa L. species have been used as wound healing and diuretic agents.
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Key Findings & Data:This study was performed on methanolic extract of the roots of A. azurea Miller var. azurea was resulted in the isolation and structure elucidation of four flavonol glycosides, kaempferol 3-O-$\beta$-glucopyranoside (=Astragalin, 1), quercetin 3-O-$\beta$-glucopyranoside (=Isoquercitrin, 2), quercetin 3-O-a-rhamnopyranosyl (l'"$\rightarrow$6")-$\beta$-glucopyranoside (=Rutin, 3), kaempferol 3-O-a-rhamnopyranosyl (l'"$\rightarrow$6")-$\beta$-glucopyranoside (4) and a phenolic acid, rosmarinic acid (5).
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Conclusion & Impact:This is the first report on the isolation of phenolic compounds from the roots of A. azurea.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

In Turkish folk medicine, Anchusa L. species have been used as wound healing and diuretic agents. This study was performed on methanolic extract of the roots of A. azurea Miller var. azurea was resulted in the isolation and structure elucidation of four flavonol glycosides, kaempferol 3-O-$\beta$-glucopyranoside (=Astragalin, 1), quercetin 3-O-$\beta$-glucopyranoside (=Isoquercitrin, 2), quercetin 3-O-a-rhamnopyranosyl (l'"$\rightarrow$6")-$\beta$-glucopyranoside (=Rutin, 3), kaempferol 3-O-a-rhamnopyranosyl (l'"$\rightarrow$6")-$\beta$-glucopyranoside (4) and a phenolic acid, rosmarinic acid (5). The structures of the isolated compounds were determined by spectroscopic methods [ID and 2D NMR spectra and MS]. This is the first report on the isolation of phenolic compounds from the roots of A. azurea.

Özet

Tilrk halk hekimliğinde Anchusa L. türleri yara iyi edici ve diüretik ajanlar olarak kullanılmaktadır. A. azurea Miller var. azurea nın köklerinin metanol ektresi üzerinde gerçekleştirilen bu çalisma 4 flavonol glikozitin: kemferol 3-O-$\beta$-glukopiranozit (=Astragalin, 1), kersetin 3-O-$\beta$-glukopiranozit (=Izokersitrin, 2), kersetin 3-O-a-ramnopiranozil (1 '"$\rightarrow$6")-$\beta$-glukopiranozit (=Rutin, 3) ve kemferol 3-O-a-ramnopiranozil (1 '"$\rightarrow$6")-$\beta$-glukopiranozit (4) ve bir fenolik asitin: rozmarinik asit (5) izolasyonu ve yapı aydınlatması He sonuclanmistır. hole edilen bileşiklerin yapılan spektroskopik yöntemlerle [ID ve 2D NMR spektrumu ve MS] saptanmistır. A. azurea köklerinden fenolik bileşiklerin izolasyonu ilk defa kaydedilmiştir.

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Cite This Article

KURUÜZÜM-UZ, A., GÜVENALP, Z., KAZAZ, C., DEMİREZER, L. Ö. (2013). Anchusa azurea var. azured'xvm köklerinden elde edilen fenolik bileşikler. Turkish Journal of Pharmaceutical Sciences, Cilt: 10 - Sayı: 2, 177–184. https://ajindex.com/articles/404087

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