Journals / Turkish Journal of Pharmaceutical Sciences / 2017 / Cilt: 14 - Sayı: 3

Substance Abuse Profiles of Patients Admitted to the Alcohol and Drug Addiction Research, Treatment, and Education Center in Turkey

Alkol ve Madde Bağımlılığı Araştırma, Tedavi ve Eğitim Merkezi Birimi'nde Yatan Hastaların Madde Kullanım Profili-Türkiye

Pages
294–303
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Our results show differences to the literature regarding the consumption of synthetic cannabinoids because the variety of synthetic cannabinoids change rapidly around the world each year.

📌 3 Key Takeaways

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Objective & Hypothesis:To determine the substance abuse profiles of patients treated a Drug Addiction Research, Treatment, and Education Center (AMATEM) in association with the percentage of substance use distribution and multiple substance use in their urine samples.
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Key Findings & Data:For this, we retrospectively evaluated the urine sample analysis reports of 600 male and female patients aged 13 to 65 years who were treated at the AMATEM unit of İstanbul Neuropsychiatry Hospital between January 1st, 2015, and December 12th, 2015.
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Conclusion & Impact:Our results show differences to the literature regarding the consumption of synthetic cannabinoids because the variety of synthetic cannabinoids change rapidly around the world each year.
🔬Design:Research Article
📍Scope:2015 Verileri
⚙️Variables:Domain Parameters

Abstract

To determine the substance abuse profiles of patients treated a Drug Addiction Research, Treatment, and Education Center (AMATEM) in association with the percentage of substance use distribution and multiple substance use in their urine samples. For this, we retrospectively evaluated the urine sample analysis reports of 600 male and female patients aged 13 to 65 years who were treated at the AMATEM unit of İstanbul Neuropsychiatry Hospital between January 1st, 2015, and December 12th, 2015. Materials and Methods: The urine samples were sent to Üsküdar University Advanced Toxicology Analysis Laboratory and were analyzed using a UPLC tandem mass spectrometer (UPLC-MS/MS). To determine the substance use profiles of the patients applying to AMATEM, statistical assessment was performed on the analysis reports of the patients. Results: When the analysis reports of the 600 urine samples were examined, 293 patients were identified to have used addictive substances. The substances most frequently detected in the urine samples were respectively: cannabis, alcohol, morphine, cocaine, synthetic cannabinoids, 3,4-Methylenedioxymethamphetamine, and amphetamine. Conclusion: The findings in our study resemble the rates of cannabis use by the young population throughout the world. Our results show differences to the literature regarding the consumption of synthetic cannabinoids because the variety of synthetic cannabinoids change rapidly around the world each year.

Özet

Amaç: Çalışmamızın amacı, AMATEM biriminde tedavi gören hastaların madde kullanım profilini onların idrar örneklerindeki madde kullanım yüzde dağılımlarına ve çoklu madde kullanımlarına göre belirlemektir. Bunun için, İstanbul Nöropsikiyatri Hastanesi AMATEM biriminde 1 Ocak 2015 - 12 Aralık 2015 tarihleri arasında tedavi gören 13 ve 65 yaş aralığında erkek ve kadın 600 hastanın idrar örneklerinin analiz raporları retrospektif olarak değerlendirildi.Gereç ve Yöntemler: İdrar örnekleri Üsküdar Üniversitesi İleri Toksikoloji Analiz Laboratuvarı'na gönderildi ve orada UPLC kütle spektrometresi ile (UPLC-MS/MS) analiz edildi. AMATEM birimine başvuruda bulunan hastaların madde kullanım profillerini tanımlamak için hastaların analiz raporları üzerinden istatistiksel değerlendirme yapılmıştır.Bulgular: Altı yüz idrar örneğinin analiz raporu incelendiğinde, hastaların 293'ünde bağımlılık yapıcı madde kullanımı belirlenmiştir. İdrar örneklerinde çoğunlukla tespit edilen maddeler sırasıyla; esrar, alkol, morfin, kokain, sentetik kannabinoitler, 3,4-metilendioksimetamfetamin ve amfetamindir.Sonuç: Çalışmamızın sonuçları bütün dünyada genç nüfus tarafından esrar kullanım oranı ile benzerlik göstermektedir. Ayrıca, sentetik kannabinoitlerin çeşitliliği her yıl dünyada hızla değiştiği için çalışmamızın sonuçları ve literatüre sonuçları sentetik kannabinoit tüketimi konusunda farklılık göstermektedir.

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Cite This Article

CANBOLAT, F., KUL, A., ÖZDEMİR, M., ATİK, U., AYDIN, A., ÖZDEN, S. T., TARHAN, K. N. (2017). Substance Abuse Profiles of Patients Admitted to the Alcohol and Drug Addiction Research, Treatment, and Education Center in Turkey. Turkish Journal of Pharmaceutical Sciences, Cilt: 14 - Sayı: 3, 294–303. https://ajindex.com/articles/403982

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