Journals / Turkish Journal of Pharmaceutical Sciences / 2006 / Cilt: 3 - Sayı: 3

Türkiye'de şarap yapımında kullanılan beyaz ve kırmızı üzümlerden elde edilen tohum ekstrelerinin karşılaştırmalı serbest radikal süpürücü kapasitesi

Comparative free radical scavenging capacity of the seed extracts obtained from the white and red grape berries used for wine-making in Turkey

Pages
177–185
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Most of the extracts displayed significant DPPH. scavenger activity.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Free radical scavenger capacity of the polyphenolic fractions obtained from ethyl acetate extracts of the seeds of sixteen red or white-colored samples of grape (Vitis vinifera-Vitaceae) species cultivated in Turkey has been determined in this study.
📊
Key Findings & Data:On this purpose, the scavenger activity of V. vinifera extracts was evaluated via stable free radical 1,1-diphenyl-2-picryl hydrazyl (DPPH.) and superoxide radical (O2-.) generated by xanthine/xanthine oxidase (XOD) system.
💡
Conclusion & Impact:Most of the extracts displayed significant DPPH. scavenger activity.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Vitis · Tohumlar · Serbest radikal süpürücüler

Abstract

Free radical scavenger capacity of the polyphenolic fractions obtained from ethyl acetate extracts of the seeds of sixteen red or white-colored samples of grape (Vitis vinifera-Vitaceae) species cultivated in Turkey has been determined in this study. On this purpose, the scavenger activity of V. vinifera extracts was evaluated via stable free radical 1,1-diphenyl-2-picryl hydrazyl (DPPH.) and superoxide radical (O2-.) generated by xanthine/xanthine oxidase (XOD) system. DPPH. scavenger capacity of the extracts has been compared with the same concentrations of the known antioxidants such as BHT, vitamin C, gallic acid and quercetin. Vitamin C and gallic acid have been also used to compare O2-. scavenger capacity of the extracts. Most of the extracts displayed significant DPPH. scavenger activity.

Özet

Bu çalışmada, Türkiye'de kültürü yapılan 16 çeşit kırmızı veya beyaz üzüm (Vitis vinifera L.-Vitaceae) örneklerinin tohumlarının etilasetat ekstrelerinden elde edilen polifenolik fraksiyonlarýn serbest radikal süpürücü etkileri tayin edilmiştir. Bu amaçla, V. vinifera ekstrelerinin süpürücü aktivitesi, stabil serbest radikal 1,1-difenil-2-pikril hidrazil (DPPH.) ve ksantin/ksantin oksidaz (XOD) sisteminin yarattığı süperoksit radikali (O2-.) aracılığı ile değerlendirilmiştir. Ekstrelerin DPPH. süpürücü aktivitesi; BHT, vitamin C, gallik asit ve kersetin gibi bilinen antioksidanların aynı konsantrasyonları ile karşılaştırılmıştır. Vitamin C ve gallik asit, ekstrelerin (O2-.) süpürücü kapasitesini karşılaştırmak için de kullanılmıştır. Ekstrelerin çoğu dikkate değer DPPH. süpürücü etki göstermiştir.

🔖

Cite This Article

ÇÖLKESEN, A., AYDIN, A., IŞIMER, A., ORHAN, İ., ŞENER, B. (2006). Türkiye'de şarap yapımında kullanılan beyaz ve kırmızı üzümlerden elde edilen tohum ekstrelerinin karşılaştırmalı serbest radikal süpürücü kapasitesi. Turkish Journal of Pharmaceutical Sciences, Cilt: 3 - Sayı: 3, 177–185. https://ajindex.com/articles/403859

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Halliwel, B., Gutteridge, J.M.C., Cross, C.E., "Free radicals, antioxidants and human disease: where are we now?" Journal of Laboratory and Clinical Medicine, 199, 598-620, 1992
  2. Schaller, B., "Prospects for the future: the role of free radicals in the treatment of stroke" Free Radical Biology and Medicine, 38, 411-425,2005
  3. Hocman, G., "Prevention of cancer: vegetables and plants" Comparative Biochemistry and Physiology, 93, 201-212, 1989
  4. Bravo, L., "Polyphenols: Chemistry, dietary sources, metabolism, and nutritional significance" Nutritional Reviews, 56, 317-333, 1998
  5. Jovanovic, S.V., Steenken, S., Tosic, M., Marjanovic, B., Simic, M.G., "Flavonoids as antioxidants" Journal of American Chemical Society, 116, 4846-4851, 1994
  6. Salah, N., Miller, N.J., Paganda, G., Tijburg, L., Bolwell, G.P., Rice-Evans, C.A., "Polyphenolic flavanols as scavengers of aqueous phase radicals and chain-breaking antioxidants" Archives of Biochemistry and Biophysics, 322, 339-346, 1995
  7. Rice-Evans, C.A., Miller, N.J., Paganda, G., " Structure -antioxidantacti v ityrelationships of flavonoids and phenolicacids " Free Radical Biology and Medicine, 20, 933-956, 1996
  8. Banerjee, B.; Trivedi, M.;Bagchi,D.,"Beneficial effect of grape seed proant h ocyanidin extract in the treatment of chronic pancreatitis " American Journal of Gastroenterology, 93,1653- 1655,1998
  9. Frankel, E.N., Meyer, A. S., " Antioxidantsingrapes and grapejuices and t heirpotential health effects" Pharmaceutical Biology, 36, 14-20, 1998
  10. Facino, R.M., Carini, M.,Aidini, G., Berti, F., Rossoni,G.,Bombardelli, E., Morazzoni,P., " Diet enriched with procyanidins enhances antioxidant acti vity and reduces myocardial post - ischemic damage in rats " Life Sciences, 64, 627-642, 1999
  11. Alp, S., "Hititlerde Şarkı, Müzik ve Dans: Hitit Çağında Anadolu'da Üzüm ve Şarap", Kavaklıdere Kültür Yayınları, Ankara, 1999
  12. Gaulejac, N.S.C., Glories, Y., Gaulejac, N.V., "Free radical scavenging effect of anthocyanins in red wine" Food Research International, 32, 327-333, 1999
  13. Brand-Williams, W., Cuvelier, M.E., Berset, C, "Use of a free radical method to evaluate antioxidant activity" Lebensmittel Wissenschaft Technologie, 28, 25-30, 1999
  14. Orhan, I., Aydın, A., Çölkesen, A., Şener, B., Işımer, A., "Free radical scavenging activities of some edible fruit seeds" Pharmaceutical Biology, 41, 163-165, 2003
  15. Latruffe, N., Delmas, D., Jannin, B., Malki, M.C., Passilly-Degrace