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Journals / Turkish Journal of Pharmaceutical Sciences / 2012 / Cilt: 9 - Sayı: 2

CHEMICAL CHARACTERIZATION AND ANTIMICROBIAL EVALUATION OF STACHYS CITRINA SUBSP. CITRINA ESSENTIAL OIL

Stachys citrina subsp. citrina Uçucu Yağının Kimyasal Karakterizasyonu ve Antimikrobiyal Değerlendirilmesi

GÖKALP İŞCAN
Betül DEMİRCİ
Fatih DEMİRCİ
Y. Bülent KÖSE
K.Hüsnü Can BAŞER
Pages
219–224
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Especially C. glabrata was inhibited at a concentration of 0.078 mg/mL of the oil.

📌 3 Key Takeaways

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Objective & Hypothesis:Flowering aerial parts of Stachys citrina Boiss. et Heldr. subsp. citrina (Lamiaceae) being endemic for Turkey were subjected to hydrodistillation to obtain the essential oil which was further analysed by GC-FID and GC-MS, simultaneously. 36 constituents were determined in the oil, where ?-pinene (29.8%) and ?-phellandrene (13.6%) were identified as the main components.
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Key Findings & Data:The oil showed weak inhibitory effects against the tested bacteria panel (1.25 to 5.0 mg/mL, MIC) whereas the Candida strains were inhibited at lower concentrations of the oil.
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Conclusion & Impact:Especially C. glabrata was inhibited at a concentration of 0.078 mg/mL of the oil.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Flowering aerial parts of Stachys citrina Boiss. et Heldr. subsp. citrina (Lamiaceae) being endemic for Turkey were subjected to hydrodistillation to obtain the essential oil which was further analysed by GC-FID and GC-MS, simultaneously. 36 constituents were determined in the oil, where ?-pinene (29.8%) and ?-phellandrene (13.6%) were identified as the main components. The anticandidal and antibacterial effects of the oil were evaluated by using microdilution method. The oil showed weak inhibitory effects against the tested bacteria panel (1.25 to 5.0 mg/mL, MIC) whereas the Candida strains were inhibited at lower concentrations of the oil. Especially C. glabrata was inhibited at a concentration of 0.078 mg/mL of the oil.

Özet

Türkiye için endemik bir tür olan Stachys citrina Boiss. et Heldr. subsp. citrina (Lamiaceae) bitkisinin çiçekli toprak üstü kısımlarından su distilasyonu ile elde edilen uçucu yağın GC-FID ve GCMS sistemleri ile eş zamanlı analizleri gerçekleştirilmiştir. Yağda 36 bileşik tespit edilmiş, ?-pinen (%29.8) ve ?-fellandren (%13.6) ana bileşikler olarak belirlenmiştir. Uçucu yağın antikandidal ve antimikrobiyal etkileri mikrodilüsyon yöntemi ile değerlendirilmiştir. Uçucu yağ yağ, test edilen bakterilere karşı daha etkisiz kalmakla birlikte (MİK; 1.25-5.0 mg/mL), Candida serisi yağın nispeten daha düşük konsantrasyonlarında inhibe olmuştur. Özellikle C. glabrata'nın, uçucu yağın 0.078 mg/mL'lik konsantrasyonunda inhibe olduğu belirlenmiştir.

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Cite This Article

İŞCAN, G., DEMİRCİ, B., DEMİRCİ, F., KÖSE, Y. B., BAŞER, K. C. (2012). CHEMICAL CHARACTERIZATION AND ANTIMICROBIAL EVALUATION OF STACHYS CITRINA SUBSP. CITRINA ESSENTIAL OIL. Turkish Journal of Pharmaceutical Sciences, Cilt: 9 - Sayı: 2, 219–224. https://ajindex.com/articles/403829

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