SavedAdd your journal

Journals / Turkish Journal of Pharmaceutical Sciences / 2010 / Cilt: 7 - Sayı: 2

Vitex agnus-castus L. meyvalarndan major iki flavonoit

Two major flavonoids from the fruits of vitex agnus-castus L.

Nurgün KÜÇÜKBOYACI
BİLGE ŞENER
Pages
119–126
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This is the first report for the presence of casticin and artemetin in V. agnus-castus growing in Turkey.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:From the ethanolic extract of the fruits of Vitex agnus-castus L. (Verbenaceae), two main flavonoid constituents, casticin and artemetin, were isolated by means of chromatographic methods.
📊
Key Findings & Data:The structure elucidation of the isolated compounds was established on the basis of spectroscopic methods (UV, IR, EMS, ID and 2D NMR).
💡
Conclusion & Impact:This is the first report for the presence of casticin and artemetin in V. agnus-castus growing in Turkey.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

From the ethanolic extract of the fruits of Vitex agnus-castus L. (Verbenaceae), two main flavonoid constituents, casticin and artemetin, were isolated by means of chromatographic methods. The structure elucidation of the isolated compounds was established on the basis of spectroscopic methods (UV, IR, EMS, ID and 2D NMR). This is the first report for the presence of casticin and artemetin in V. agnus-castus growing in Turkey.

Özet

Vitex agnus-castus L. (Verbenaceae) meyvalarinin etanollü ekstresinden kastisin ve artemetin olmak üzere iki tane flavonoit kromatografik metotlarla izole edilmiştir, izole edilen bileşiklerin yapı tayinleri spektral metotlara (UV, IR, EIMS, İD ve 2D NMR) dayanarak aydınlatılmıştır. Türkiye'de yetişen V. agnus-castus 'ta kastisin ve artemetin 'in varlığı ilk defa bu çalışma ile bildirilmektedir.

🔖

Cite This Article

KÜÇÜKBOYACI, N., ŞENER, B. (2010). Vitex agnus-castus L. meyvalarndan major iki flavonoit. Turkish Journal of Pharmaceutical Sciences, Cilt: 7 - Sayı: 2, 119–126. https://ajindex.com/articles/403801

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Tutin, T.G., Heywood V.H., Burges N.A., Valentine D.H., Walters S.M., Webb, D.A., Flora Europaea, Vol. 3, pp. 122, Cambridge University Press, Cambridge, 1972
  2. Townsend, C.C., Vitex L. in: Flora of Turkey and East Aegean Islands, Ed.: P.H. Davis, Vol.7, 34-35, University Press, Edinburgh, 1982
  3. Baytop, T., A Dictionary of Vernacular Names of Wild Plants of Turkey, No:578, pp. 132, Publication of the Turkish Language Society, Ankara, 1994
  4. Mahady, G.B., Dietz, B., Michel, J., Engle, J., Sagraves, R., Chasteberry (Vitex agnus-castus). in: Encyclopedia of Dietary Supplements, Ed.: P.M. Coates, pp. 95-103, Marcel Dekker, New York, 2005
  5. Wuttke, W., Jarry, H., Christoffel, V., Splengler, B., Seidlova-Wuttke, D., “Chaste tree (Vitex agras-casto)-pharmacology and clinical indications” Phytomedicine, 10, 348-357, 2003
  6. Baytop, T., Therapy with Medicinal Plants in Turkey (Past and Present), No. 3255, pp. 226, Publications of the İstanbul University, İstanbul, 1999
  7. Honda, G., Yeşilada, E., Tabata, M., Sezik, E., Fujita, T., Takeda, Y., Takaishi, Y., Tanaka, T., “Traditional medicine in Turkey VI. Folk medicine in West Anatolia: Afyon, Kütahya, Denizli, Muğla, Aydın provinces” J. Ethnopharmacol., 53, 75-87, 1996
  8. Strait, M., Rimpler, H., Haensel, R., “Flavonoids from Vitex agnus-castus” Experientia, 18, 72, 1962
  9. Gomaa, C.S., El-Moghazy, M.A., Halim, F.A., El-Sayyad, A.E., “Flavonoids and iridoids from Vitex agnus-castus” Planta Med., 33(3), 277, 1978
  10. Wollenweber, E., Mann, K., “Flavonols from fruits of Vitex agnus-castus” Planta Med., 48, 126-127, 1983
  11. Hirobe, C, Qiao, Z.-S., Takeya, K., Itokawa, H., “Cytotoxic flavonoids from Vitex agnus-castus” Phytochemistry, 46(3), 521-524, 1997
  12. Hadju, Z., Hohmann, J., Forgo, P., Martinek, T., Dervarics, M., Zupko, I., Falkay, G., Cossuta, D., Mathe, I., “Diterpenoids and flavonoids from the fruits of Vitex agnus-castus and antioxidant activity of the fruit extracts and their constituents”Phytotherapy Res., 21(4), 391-394, 2007
  13. Belie I., Bergant-Dolar, J., Morton, R.A., “Constituents of Vitex agnus-castus seeds. I. Casticin” J. Chem. Soc, 2523-2525, 1961
  14. Ramazanov, N., “Ectysteroids and iridodial glycosides from Vitex agnus-castus” Chem. Nat. Comp., 40(3), 299-300, 2004
  15. Kuruüzüm-Uz, A., Stroch, K., Demirezer, L.Ö., Zeeck, A., “Glucosides from Vitex agnus-castus” Phytochemistry, 63, 959-964, 2003
  16. Hoberg, E., Orjala, J., Meier, B., Sticher, O., “Diterpenoids from the