Journals / Turkish Journal of Pharmaceutical Sciences / 2010 / Cilt: 7 - Sayı: 3

Scorzonera latifolia köklerinden izole edilen dihidroizokumarin türevi bileşikler

Dihydroisocoumarin derivatives isolated from the roots of scorzonera latifolia

Pages
205–212
DOI
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⚡ TL;DR(Too Long; Didn't Read)

The structures were determined using spectroscopic methods ('H-NMR, 13C-NMR, HMBC, HSQQ COSY, TOCSY, NOESY, DEPT) and chemical correlations with known compounds that have been described in the literature.

📌 3 Key Takeaways

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Objective & Hypothesis:Scorzonera latifolia (Fisch. & Mey.) DC. is a perennial herb that grows in central and eastern region of Anatolia, Turkey.
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Key Findings & Data:The compounds were identified as (±) hydrangenol and (-)-scorzotomentosin 4'-0-P-glucopyranoside.
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Conclusion & Impact:The structures were determined using spectroscopic methods ('H-NMR, 13C-NMR, HMBC, HSQQ COSY, TOCSY, NOESY, DEPT) and chemical correlations with known compounds that have been described in the literature.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Scorzonera latifolia (Fisch. & Mey.) DC. is a perennial herb that grows in central and eastern region of Anatolia, Turkey. A traditional mastic named yah sakızı has been prepared from the roots of this plant and used as an analgesic in Turkish folk medicine. In this study, the methanolic extract obtained from the roots of S. latifolia were investigated for the chemical composition. Two dihydroisocoumarin derivatives were isolated from the roots. The compounds were identified as (±) hydrangenol and (-)-scorzotomentosin 4'-0-P-glucopyranoside. The structures were determined using spectroscopic methods ('H-NMR, 13C-NMR, HMBC, HSQQ COSY, TOCSY, NOESY, DEPT) and chemical correlations with known compounds that have been described in the literature.

Özet

Scorzonera latifolia (Fisch. & Mey.) DC. orta ve doğu Anadolu ’da yetişen gok yilhk bir bitkidir.Bu bitkinin köklerinden Türk halk tıbbında analjezik olarak kullamlan, yah sakızi olarak isimlendirilen geleneksel bir sahz elde edilmektedir. Bu gahsmada, S latifolia köklerinden elde edilen metanollü ekstre kimyasal bileşimi agisından araştinlmistır. İzole edilen bileşikler (±) hidrangenol ve (-)-skorzotomentozin 4'-0-P-glukopiranozit olarak tammlanmistır. Bileşiklerin yapılan spektroskopik metotlar ('H-NMR, 13C-NMR, HMBC, HSQQ COSY, TOCSY, NOESY, DEPT) kullamlarak aydınlatılmis ve literatiir bilgileriyle doğrulanmistır.

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Cite This Article

ÇİTOĞLU, S. G., ACIKARA, Ö. B., DALL'ACQUA, A. (2010). Scorzonera latifolia köklerinden izole edilen dihidroizokumarin türevi bileşikler. Turkish Journal of Pharmaceutical Sciences, Cilt: 7 - Sayı: 3, 205–212. https://ajindex.com/articles/403795

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References (14)

  1. Özgen, U., Mavi, A., Terzi, Z., Coşkun, M., Yıldırım, A., “Antioxidant activities and total phenolic compounds amount of some Asteraceae species” Turk J. Pharm. Sci., 1(3), 203-216, 2004
  2. Bohm, B.A., Stuessy, T.F., Flavonoids of the Sunflower Family (Asteraceae), pp. 336, Springer Wien. New York, 2007
  3. Paraschos, S., Magiatis, P., Kalpoutzakis, E., Harvala, C., Skaltsounis, A.L., “Tree new dihydroisocoumarins from the Greek endemic species Scorzonera cretica” J. Nat. Prod., 64, 1585-87, 2001
  4. Chamberlain, D.F., Scorzonera L. in: Flora of Turkey and The East Aegean Islands, Ed: P.H. Davis, vol. 5, pp. 632-657, University Press. Edinburgh, 1975
  5. Douglas, J., “Scorzonera hispanica- a European vegetable” Crop and Food Research, Available from: URL: http://www.crop.cri.nz/home/products-services/publications /broadsheets/ 028scorzonera. pdf, 2005
  6. Tsevegsuren, N., Edrada, R.A., Lin, W., Ebel, R., Torre, C., Ortlepp, S., Wray, V., Proksch, P., “Four new natural products from mongolian medicinal plants Scorzonera divaricata and Scorzonera pseudodivaricata (Asteraceae)” Planta Med., 72, 967, 2006
  7. Wang, Y., Edrada-Ebel, R.A., Tsevegsuren, N., Sendker, J., Braun, M., Wray, V., Lin, W., Proksch, P., “Dihydrostilbene derivatives from the mongolian medicinal plant Scorzonera radiata” J. Nat. Prod., 72, 671–675, 2009
  8. Zidorn, C., Ellmerer-Müller, E.P., Stuppner, H., “Sesquiterpenoids from Scorzonera hispanica L.” Pharmazie, 55, 550-551, 2000
  9. Zidorn, C., Ellmerer-Müller, E.P., Stuppner, H., “Tyrolobibenzyls-novel secondary metabolites from Scorzonera humilis L.” Helv. Chim. Acta, 83, 2920-2925, 2000
  10. Zidorn, C., Ellmerer, E.P., Sturm, S., Stuppner, H., “Tyrolobibenzyls E and F from Scorzonera humilis and distribution of caffeic acid derivatives, lignans and tyrolobibenzyls in European taxa of the subtribe Scorzonerinae (Lactuceae, Asteraceae)” Phytochemistry, 63, 61-67, 2003
  11. Zhu, Y., Wu, Q., Hu, P., Wu, W., “Biguaiascorzolides A and B, Two novel dimeric guaianolides with a rare skeleton, from Scorzonera austriaca” Food Chem., 114, 1316-1320, 2009
  12. Özkan Gençler, A.M., Koyuncu, M., “Traditional medicinal plants used in Pınarbaşı area (Kayseri-Turkey)” Turk J. Pharm. Sci., 2(2), 63-82, 2005
  13. Ünal, O., Göktürk, R.S., “A new species of Scorzonera L. (Asteraceae) from south Anatolia, Turkey” Bot. J. Linn. Soc., 142, 465-468, 2003
  14. Duran, A., Hamzaoğlu, E., “A new species of Scorzonera (Asteraceae) from South Anatolia, Turkey” B