Journals / The Anatolian Journal of Cardiology / 2021 / Cilt: 25 - Sayı: 3

Time for a new paradigm shift in myocardial infarction

Pages
156–162
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This review aimed to discuss the origins, evidence base, and limitations of STEMI/non-STEMI paradigm and to call for a new paradigm shift to the occlusion MI (OMI)/non-OMI.

📌 3 Key Takeaways

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Objective & Hypothesis:The ST-elevation myocardial infarction (STEMI)/non-STEMI paradigm per the current guidelines has important limitations.
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Key Findings & Data:It misses a substantial proportion of acute coronary occlusions (ACO) and results in a significant amount of unnecessary catheterization laboratory activations.
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Conclusion & Impact:This review aimed to discuss the origins, evidence base, and limitations of STEMI/non-STEMI paradigm and to call for a new paradigm shift to the occlusion MI (OMI)/non-OMI.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

The ST-elevation myocardial infarction (STEMI)/non-STEMI paradigm per the current guidelines has important limitations. It misses a substantial proportion of acute coronary occlusions (ACO) and results in a significant amount of unnecessary catheterization laboratory activations. It is not widely appreciated how poor is the evidence base for the STEMI criteria; the recommended STEMI cutoffs were not derived by comparing those with ACO with those without and not specifically designed for distinguishing patients who would benefit from emergency reperfusion. This review aimed to discuss the origins, evidence base, and limitations of STEMI/non-STEMI paradigm and to call for a new paradigm shift to the occlusion MI (OMI)/non-OMI.

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Cite This Article

ASLANGER, E., MEYERS, H. P., SMİTH, S. W. (2021). Time for a new paradigm shift in myocardial infarction. The Anatolian Journal of Cardiology, Cilt: 25 - Sayı: 3, 156–162. https://ajindex.com/articles/403152

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References (12)

  1. Weigert C. Ueber die pathologiische Gerinnugs-Vorgange. Arch Path Anat (Virchow) 1880
  2. [Crossref] 2. Herrick JB. Clinical features of sudden obstruction of the coronary arteries. JAMA 1912
  3. [Crossref] 3. Pardee HEB. An electrocardiographic sign of coronary artery obstruction. Arch Intern Med 1920
  4. [Crossref] 4. Sherry S. Personal reflections on the development of thrombolytic therapy and its application to acute coronary thrombosis. Am Heart J 1981
  5. [Crossref] 5. Rentrop KP, Blanke H, Karsch KR, Wiegand V, Köstering H, Oster H, et al. Acute myocardial infarction: intracoronary application of nitroglycerin and streptokinase. Clin Cardiol 1979
  6. [Crossref] 6. Streptokinase in acute myocardial infarction. European Cooperative Study Group for Streptokinase Treatment in Acute Myocardial Infarction. N Engl J Med 1979
  7. [Crossref] 7. DeWood MA, Spores J, Notske R, Mouser LT, Burroughs R, Golden MS, et al. Prevalence of total coronary occlusion during the early hours of transmural myocardial infarction. N Engl J Med 1980
  8. [Crossref] 8. Effectiveness of intravenous thrombolytic treatment in acute myocardial infarction. Gruppo Italiano per lo Studio della Streptochinasi nell'Infarto Miocardico (GISSI). Lancet 1986
  9. Ryan TJ, Anderson JL, Antman EM, Braniff BA, Brooks NH, Califf RM, et al. ACC/AHA guidelines for the management of patients with acute myocardial infarction. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Acute Myocardial Infarction). J Am Coll Cardiol 1996
  10. Indications for fibrinolytic therapy in suspected acute myocardial infarction: collaborative overview of early mortality and major morbidity results from all randomised trials of more than 1000 patients. Fibrinolytic Therapy Trialists' (FTT) Collaborative Group. Lancet 1994
  11. [Crossref] 11. Ryan TJ, Antman EM, Brooks NH, Califf RM, Hillis LD, Hiratzka LF, et al. 1999 update: ACC/AHA guidelines for the management of patients with acute myocardial infarction. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Acute Myocardial Infarction). J Am Coll Cardiol 1999
  12. [Crossref] 12. Braunwald E, Antman EM, Beasley JW, Califf RM, Cheitlin MD, Hochman JS, et al. ACC/AHA guidelines for the managem