Journals / Tekstil ve Mühendis / 2021 / Cilt: 28 - Sayı: 122

EFFECT OF DIFFERENT SOLVENT SYSTEMS ON FIBER MORPHOLOGY AND PROPERTY OF ELECTROSPUN PCL NANO FIBERS

Pages
61–75
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Porous electrospun fiber is better for cell development.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Polycaprolactone (PCL) is biocompatible aliphatic polyester with many possible applications in the medical field.
📊
Key Findings & Data:Dichloromethane (DCM) was used as a good solvent in mixtures with a poor solvent, dimethyl sulfoxide (DMSO), in order generate to pores on the fiber surface.
💡
Conclusion & Impact:Porous electrospun fiber is better for cell development.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Polycaprolactone (PCL) is biocompatible aliphatic polyester with many possible applications in the medical field. Porous electrospun Polycaprolactone (PCL) fibers were produced through a non-solvent induced phase separation mechanism, using binary solvent systems with different properties. The effect of single and binary solvent systems on the fiber size and surface morphology were investigated. Dichloromethane (DCM) was used as a good solvent in mixtures with a poor solvent, dimethyl sulfoxide (DMSO), in order generate to pores on the fiber surface. The effect of polymer concentrations (12%, 14% and 16%) w/v and solvents ratios (9:1, 7:3 and 5:5) v/v were investigated on nanofiber formation. During electrospun fiber production, the flow rate was 0.12mL/h, the distance between needle and collector was 15cm and the applied voltage was 12kV. SEM micrographs showed successfull production of PCL nanofibers with different solvents. With increasing the polymer concentration and changing the ratio of the solvents porous PCL electrospun nanofiber was produced. In binary solvent systems 16% PCL polymers and (7:3) % solvents ratio solution make even, beads free, smooth and porous PCL electrospun fiber. Combining the inherent properties of the PCL matrix with the characteristic of nanofibrous mats, result in promising materials that can be suitable for different applications, including biomedical applications. The advantages of nanofibrous structures include large surface area, small diameter of pores and high porosity, which make them of great interest in different applications. Porous electrospun fiber is better for cell development.

🔖

Cite This Article

KHAN, M. T., MAMUN, M. A. A., MIA, R., XU, A., RASHID, M. M. (2021). EFFECT OF DIFFERENT SOLVENT SYSTEMS ON FIBER MORPHOLOGY AND PROPERTY OF ELECTROSPUN PCL NANO FIBERS. Tekstil ve Mühendis, Cilt: 28 - Sayı: 122, 61–75. https://ajindex.com/articles/395820

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (3)

  1. Hoskins, J. N., & Grayson, S. M. J. M. (2009). Synthesis and degradation behavior of cyclic poly (ε-caprolactone). Macromolecules, 42(17), 6406-6413. Doi: 10.1021/ma9011076 Kim, H. H., Kim, M. J., Ryu, S. J., Ki, C. S., Park, Y. H. J. F. (2016). Effect of fiber diameter on surface morphology, mechanical property, and cell behavior of electrospun poly (ε- caprolactone) mat. Polymer, 17(7), 1033-1042.
  2. Woodruff, M. A., & Hutmacher, D. W. J. P. i. p. s. (2010). The return of a forgotten polymer—Polycaprolactone in the 21st century. Progress in Polymer Science, 35(10), 1217-1256. Doi: 10.1016/j.progpolymsci.2010.04.002 Asandei, A. D (2011). Early Transition Metal Catalyzed Living Radical and Ring Opening Polymerizations for Complex Copolymer Architectures. Paper presented at the 56th Annual Report on Research Under Sponsorship of The American Chemical Society Petroleum Research Fund. Huang, C.-H., Wang, F.-C., Ko, B.-T., Yu, T.-L., & Lin, C.-C. J. M. (2001). Ring-opening polymerization of ε-caprolactone and Llactide using aluminum thiolates as initiator. Macromolecules, 34(3), 356-361. Doi: 10.1021/ma0014719 Elbay Malikmammadov, Tugba Endogan Tanir, Aysel Kiziltay, Vasif Hasirci & Nesrin Hasirci (2018) PCL and PCL-based materials in biomedical applications, Journal of Biomaterials Science, Polymer Edition, 29:7-9, 863-893, DOI: 10.1080 /09205063.2017.1394711 Aydemir Sezer, U., Arslantunali, D., Aksoy, E., Hasirci, V. and Hasirci, N. (2014). Poly(ε-caprolactone) composite scaffolds loaded with gentamicin-containing β-tricalcium phosphate/gelatin microspheres for bone tissue engineering applications. J. Appl. Polym. Sci. 131, 40110, doi: 10.1002/app.40110 Sezer, U. A., Billur, D., Huri, G., Huri, P. Y., Aksoy, E. A., Terzioglu, H. (2014). In vivo performance of poly (ε- caprolactone) constructs loaded with gentamicin releasing composite microspheres for use in bone regeneration. Journal of Biomaterial and Tissue Engineering, 4(10), 786-795. Doi: doi.org/10.1166/jbt.2014.1238 De La Ossa, D. H. P., Ligresti, A., Gil-Alegre, M., Aberturas, M., Molpeceres, J., Di Marzo, V., & Suárez, A. T. (2012). Poly-ε- caprolactone microspheres as a drug delivery system for cannabinoid administration: Development, characterization and in vitro evaluation of their antitumoral efficacy. Journal of Control Release, 161(3), 927-932.
  3. Tong, S. Y., Wang, Z., Lim, P. N., Wang, W., San Thian, E. J. M. S., & C, E. (2017). Uniformly-dispersed nanohydroxapatitereinforced poly (ε-caprolactone)