Journals / Psikiyatride Güncel Yaklaşımlar / 2022 / Cilt: 14 - Sayı: 1

Role of Intestinal Microbiota in Patients with Anorexia Nervosa

Anoreksiya Nervosalı Hastalarda İntestinal Mikrobiyotanın Rolü

Pages
65–73
Publication Date
2022-03-31
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This work aims to review the existing studies to provide information about the possible role of intestinal microbiota in the pathophysiology of anorexia nervosa, characteristics of intestinal dysbiosis in patients with anorexia nervosa, and possible treatment approaches in the management of intestinal microbiota.

📌 3 Key Takeaways

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Objective & Hypothesis:Anorexia nervosa is a psychiatric disorder characterized by severe low body weight, impaired self-body image, and intense fear of gaining weight, however its etiopathogenesis is not fully known.
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Key Findings & Data:Some studies show that nutritional rehabilitation and corresponding weight restoration are not effective enough in the management of intestinal dysbiosis in patients with anorexia nervosa, but results are inconclusive.
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Conclusion & Impact:This work aims to review the existing studies to provide information about the possible role of intestinal microbiota in the pathophysiology of anorexia nervosa, characteristics of intestinal dysbiosis in patients with anorexia nervosa, and possible treatment approaches in the management of intestinal microbiota.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Anoreksiya nervoza · mikrobiyota · disbiyoz

Abstract

Anorexia nervosa is a psychiatric disorder characterized by severe low body weight, impaired self-body image, and intense fear of gaining weight, however its etiopathogenesis is not fully known. Some studies show that nutritional rehabilitation and corresponding weight restoration are not effective enough in the management of intestinal dysbiosis in patients with anorexia nervosa, but results are inconclusive. This work aims to review the existing studies to provide information about the possible role of intestinal microbiota in the pathophysiology of anorexia nervosa, characteristics of intestinal dysbiosis in patients with anorexia nervosa, and possible treatment approaches in the management of intestinal microbiota.

Özet

Özet Düşük vücut ağırlığı, bozulmuş beden algısı ve kilo alma korkusu ile karakterize psikiyatrik bir bozukluk olan anoreksiya nervozanın etiyopatogenezi tam olarak bilinmemektedir. Literatürde yer alan çalışmalar anoreksiya nervosalı hastalarda beslenme rehabilitasyonunun ve yeniden ağırlık kazanımının intestinal disbiyoz yönetiminde yeterince etkin olmadığını göstermektedir, ancak çalışmaların sonuçları karmaşıktır. Bu derlemede intestinal mikrobiyotanın anoreksiya nervosa patofizyolojisindeki olası rolü, anoreksiya nervosalı hastalarda intestinal disbiyoza ilişkin özellikler ve intestinal mikrobiyota yönetiminde olası tedavi yaklaşımları hakkında bilgi verilmesi amaçlanmıştır.

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Cite This Article

ALMASİ, N., ÇETİN, A. K., GÖKTAŞ, Z. (2022). Role of Intestinal Microbiota in Patients with Anorexia Nervosa. Psikiyatride Güncel Yaklaşımlar, Cilt: 14 - Sayı: 1, 65–73. https://ajindex.com/articles/395193

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References (8)

  1. Agrawal, M., Aroniadis, O. C., Brandt, L. J., Kelly, C., Freeman, S., Surawicz, C. ve diğerleri. (2016). The long-term efficacy and safety of fecal microbiota transplant for recurrent, severe, and complicated Clostridium difficile infection in 146 elderly individuals. Journal of Clinical Gastroenterology, 50(5), 403-407.
  2. Aizawa, E., Tsuji, H., Asahara, T., Takahashi, T., Teraishi, T., Yoshida, S. ve diğerleri. (2016). Possible association of Bifidobacterium and Lactobacillus in the gut microbiota of patients with major depressive disorder. Journal of Affective Disorders, 202, 254-257.
  3. Al Omran, Y., & Aziz, Q. (2014). The brain-gut axis in health and disease. Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease, 135-153.
  4. Arcelus, J., Mitchell, A. J., Wales, J., & Nielsen, S. (2011). Mortality rates in patients with anorexia nervosa and other eating disorders: a meta-analysis of 36 studies. Archives of General Psychiatry, 68(7), 724-731.
  5. Armougom, F., Henry, M., Vialettes, B., Raccah, D., & Raoult, D. (2009). Monitoring bacterial community of human gut microbiota reveals an increase in Lactobacillus in obese patients and Methanogens in anorexic patients. PLoS One, 4(9), e7125. Association, A. P. (2013). Diagnostic and statistical manual of mental disorders (DSM-5®): American Psychiatric Pub. Bailey, M. T., Dowd, S. E., Galley, J. D., Hufnagle, A. R., Allen, R. G., & Lyte, M. (2011). Exposure to a social stressor alters the structure of the intestinal microbiota: implications for stressor-induced immunomodulation. Brain, Behavior, and Immunity, 25(3), 397-407.
  6. Bajer, L., Kverka, M., Kostovcik, M., Macinga, P., Dvorak, J., Stehlikova, Z. ve diğerleri. (2017). Distinct gut microbiota profiles in patients with primary sclerosing cholangitis and ulcerative colitis. World Journal of Gastroenterology, 23(25), 4548. Bambury, A., Sandhu, K., Cryan, J. F., & Dinan, T. G. (2018). Finding the needle in the haystack: systematic identification of psychobiotics. British Journal of Pharmacology, 175(24), 4430-4438.
  7. Barcik, W., Boutin, R. C. T., Sokolowska, M., & Finlay, B. B. (2020). The Role of Lung and Gut Microbiota in the Pathology of Asthma. Immunity, 52(2), 241-255.
  8. Bercik, P., Denou, E., Collins, J., Jackson, W., Lu, J., Jury, J. ve diğerleri. (2011). The intestinal microbiota affect central levels of brain-derived neurotropic factor and behavior in mice. Gastroenterology, 141(2), 599-609. e593. Borgo, F., Riva, A., Benetti, A., Casiraghi, M.