The patients with Peutz-Jeghers syndrome have a high risk of developing cancer

Objective & Hypothesis:Peutz-Jeghers syndrome is an autosomal dominant disorder characterized by mucocutaneous hyperpigmentation,and intestinal and extraintestinal multiple hamartomatous polyps.

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Key Findings & Data:Development of gastrointestinal and extragastrointestinalcancer risk is markedly increased in patients with Peutz-Jeghers syndrome.

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Conclusion & Impact:Therefore, we suggest a close follow-up of patients with Peutz-Jeghers syndrome for therisk of malignancy.

🔬Design:Research Article

📍Scope:2012 Verileri

⚙️Variables:Domain Parameters

Özet

Peutz-Jeghers syndrome is an autosomal dominant disorder characterized by mucocutaneous hyperpigmentation,and intestinal and extraintestinal multiple hamartomatous polyps. Development of gastrointestinal and extragastrointestinalcancer risk is markedly increased in patients with Peutz-Jeghers syndrome. We analyzed five patientsfrom two families diagnosed with Peutz-Jeghers syndrome between 1999 and 2012. This study confirms the actualmalignancy potency of PJS. Therefore, we suggest a close follow-up of patients with Peutz-Jeghers syndrome for therisk of malignancy.

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Cite This Article

TAVUSBAY, C., KAR, H., ACAR, T., ATAHAN, K., KAMER, E. (2018). The patients with Peutz-Jeghers syndrome have a high risk of developing cancer. Turkish Journal of Surgery, Cilt: 34 - Sayı: 2, 162–164. https://ajindex.com/articles/390476

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