Journals / Çocuk Acil ve Yoğun Bakım Dergisi / 2021 / Cilt: 8 - Sayı: 3

Evaluation of Clinical and Demographic Characteristics of Patients Hospitalized in the Pediatric Intensive Care Unit due to Convulsive Status Epilepticus

Çocuk Yoğun Bakımda Konvülzif Status Epileptikus Nedeniyle Yatan Hastaların Klinik ve Demografik Özelliklerinin Değerlendirilmesi

Pages
172–176
DOI
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Conclusion: In our study, it was observed that the majority of the patients who were hospitalized in our pediatric intensive care unit due to convulsive status epilepticus were male, convulsive status epilepticus was more common in children with chronic neurological disease, benzodiazepine infusion was the first choice for treatment and Levetiracetam was the second most commonly used antiepileptic.

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: Status epilepticus is an important part of pediatric intensive care hospitalizations.
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Key Findings & Data:Results: 62.6% of cases were male and the mean age of all cases was 53.69±47.14 months.
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Conclusion & Impact:Conclusion: In our study, it was observed that the majority of the patients who were hospitalized in our pediatric intensive care unit due to convulsive status epilepticus were male, convulsive status epilepticus was more common in children with chronic neurological disease, benzodiazepine infusion was the first choice for treatment and Levetiracetam was the second most commonly used antiepileptic.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Introduction: Status epilepticus is an important part of pediatric intensive care hospitalizations. In this study, it was aimed to investigate the general characteristics and to share the clinical and demographical features of patients who were hospitalized due to convulsive status epilepticus. Methods: One hundred-thirty one cases were included in this study. Identity information of patients, presence of acute and chronic diseases, duration of intensive care stay and hospitalization, first seizure type, where they were admitted, number of seizures during intensive care follow-up, antiepileptics used in treatment and other treatments and the status of discharge-mortality were recorded. Results: 62.6% of cases were male and the mean age of all cases was 53.69±47.14 months. The most common chronic disease was epilepsy and the most common acute disease was lower respiratory tract infection. The first admission of 34.4% of the cases was due to status epilepticus, and the rate of cases accepted from other hospitals was 60.3%. During intensive care follow-up, no convulsions were observed in 77.1% of the cases. In the first treatment, benzodiazepine infusion was used in 77.1% of the cases. The median length of stay in intensive care unit was 4 days (minimummaximum=3-8 days) in the benzodiazepine infusion group, and 3 days (minimum-maximum=2-3 days) in the group that was not given benzodiazepine. The other most preferred antiepileptics were levetiracetam and phenytoin in 62.6% and 39.7% of the cases, respectively. The mortality rate was found as 2.3%. Conclusion: In our study, it was observed that the majority of the patients who were hospitalized in our pediatric intensive care unit due to convulsive status epilepticus were male, convulsive status epilepticus was more common in children with chronic neurological disease, benzodiazepine infusion was the first choice for treatment and Levetiracetam was the second most commonly used antiepileptic.

Özet

Giriş: Status epileptikus, çocuk yoğun bakım yatışlarının önemli bir kısmını oluşturmaktadır. Bu çalışmada ünitemize konvülzif status epileptikus nedeniyle yatırılan olguların genel özelliklerinin incelenmesi ve klinik ve demografik özelliklerinin paylaşılması amaçlanmıştır. Yöntemler: Bu çalışmaya 131 olgu dahil edildi. Olguların kimlik bilgileri, akut ve süreğen hastalık varlığı, yoğun bakım ve hastane yatış gün sayıları, ilk nöbet şekli, nereden kabul edildiği, yoğun bakım takibi sırasında geçirilen nöbet sayısı, tedavide kullanılan antiepileptikler ve uygulanan diğer tedaviler ve taburculuk-mortalite durumları kaydedildi. Bulgular: Olguların %62,6’sı erkekti ve tüm olguların yaş ortalaması 53,69±47,14 ay’dı. En sık görülen süreğen hastalık epilepsi, en sık görülen akut hastalık alt solunum yolu enfeksiyonu olarak bulundu. Olguların %34,4’ünün ilk başvuru şekli status epileptikus şeklinde olup, başka hastanelerden kabul edilen olgu oranı %60,3 idi. Yoğun bakım takibi sırasında olguların %77,1’inde konvülziyon görülmedi. İlk tedavide %77,1 oranında benzodiyazepin infüzyonu kullanıldı. Benzodiyazepin infüzyonu kullanılan grupta yoğun bakım yatış süresi medyan 4 (3-8) gün, kullanılmayan grupta 3 (2-3) gün’dü. İkinci sırada tercih edilen antiepileptikler %62,6 oranında levatirasetam ve %39,7 oranında fenitoin oldu. Mortalite oranımız %2,3 olarak bulundu. Sonuç: Çalışmamızda, beş yıllık süre zarfında çocuk yoğun bakım ünitemize konvülzif status epileptikus nedeniyle yatırılan olguların büyük çoğunluğunun erkek cinsiyet olduğu; süreğen nörolojik hastalığı olan çocuklarda daha sık görüldüğü, benzodiyazepin infüzyonunun ilk tercih edilen tedavi şekli olduğu ve ikinci sırada en çok kullanılan antiepileptiğin Levatirasetam olduğu görülmüştür.

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Cite This Article

BARLAS, Ü. K., AKÇAY, N., PETMEZCİ, M. T., KIHTIR, H. S., YEŞİLBAŞ, O., GÜVENÇ, K. B., ÖZÇELİK, G., ŞEVKETOĞLU, E. (2021). Evaluation of Clinical and Demographic Characteristics of Patients Hospitalized in the Pediatric Intensive Care Unit due to Convulsive Status Epilepticus. Çocuk Acil ve Yoğun Bakım Dergisi, Cilt: 8 - Sayı: 3, 172–176. https://ajindex.com/articles/389905

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