Journals / Turkish Journal of Chemistry / 2004 / Cilt: 28 - Sayı: 2

Iridoid and Phenylethanoid Glycosides from Verbascum lasianthum

Pages
227–234
Publication Date
2004-02-01
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Compounds 2-5 demonstrated scavenging properties toward the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical in TLC autographic assays.

📌 3 Key Takeaways

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Objective & Hypothesis:Three iridoid glucosides, 8-O-acethylharpagide (1), harpagoside (2), and 6-O-vanilloylajugol (3), were isolated from the roots of Verbascum lasianthum Boiss. ex Bentham.
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Key Findings & Data:In addition, 2 phenylethanoid glycosides, verbascoside {=acteoside, [b -(3,4-dihydroxyphenyl)-ethyl]-(3' -O-a -L-rhamnopyranosyl)-(4' -O-caffeoyl)-b -D-glucopyranoside} (4) and poliumoside {= [b -(3,4-dihydroxyphenyl)-ethyl]-(3',6' -O-a -L-dirhamnopyranosyl)-(4' -O-caffeoyl)-b -D-glucopyranoside} (5), were also isolated.
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Conclusion & Impact:Compounds 2-5 demonstrated scavenging properties toward the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical in TLC autographic assays.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Verbascum lasianthum · Scrophulariaceae · iridoid glucosides

Abstract

Three iridoid glucosides, 8-O-acethylharpagide (1), harpagoside (2), and 6-O-vanilloylajugol (3), were isolated from the roots of Verbascum lasianthum Boiss. ex Bentham. In addition, 2 phenylethanoid glycosides, verbascoside {=acteoside, [b -(3,4-dihydroxyphenyl)-ethyl]-(3' -O-a -L-rhamnopyranosyl)-(4' -O-caffeoyl)-b -D-glucopyranoside} (4) and poliumoside {= [b -(3,4-dihydroxyphenyl)-ethyl]-(3',6' -O-a -L-dirhamnopyranosyl)-(4' -O-caffeoyl)-b -D-glucopyranoside} (5), were also isolated. The structures of all compounds were established by spectroscopic evidence (UV, IR, 1D and 2D NMR, LC-ESIMS). Compounds 2-5 demonstrated scavenging properties toward the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical in TLC autographic assays.

Özet

Three iridoid glucosides, 8-O-acethylharpagide (1), harpagoside (2), and 6-O-vanilloylajugol (3), were isolated from the roots of Verbascum lasianthum Boiss. ex Bentham. In addition, 2 phenylethanoid glycosides, verbascoside {=acteoside, [b -(3,4-dihydroxyphenyl)-ethyl]-(3' -O-a -L-rhamnopyranosyl)-(4' -O-caffeoyl)-b -D-glucopyranoside} (4) and poliumoside {= [b -(3,4-dihydroxyphenyl)-ethyl]-(3',6' -O-a -L-dirhamnopyranosyl)-(4' -O-caffeoyl)-b -D-glucopyranoside} (5), were also isolated. The structures of all compounds were established by spectroscopic evidence (UV, IR, 1D and 2D NMR, LC-ESIMS). Compounds 2-5 demonstrated scavenging properties toward the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical in TLC autographic assays.

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Cite This Article

AKDEMİR, Z. Ş., TATLI, İ. İ. (2004). Iridoid and Phenylethanoid Glycosides from Verbascum lasianthum. Turkish Journal of Chemistry, Cilt: 28 - Sayı: 2, 227–234. https://ajindex.com/articles/382247

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