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Journals / Turkish Journal of Chemistry / 2005 / Cilt: 29 - Sayı: 2

Synthesis and Antimicrobial Activities of Some New Flavonyl Pro-drug Esters of Ampicillin

Meltem CEYLAN ÜNLÜSOY
Nurten ALTANLAR
Rahmiye ERTAN
Pages
187–191
Publication Date
2005-02-01
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Both of the compounds were active against Candida krusei and Staphylococcus aureus.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:A new series of flavonyl pro-drug esters of ampicillin (Va-b) was prepared by condensing the appropriate bromomethyl flavone with ampicillin trihydrate potassium salt.
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Key Findings & Data:Flavone derivatives and ampicillin both have good antibacterial activity.
💡
Conclusion & Impact:Both of the compounds were active against Candida krusei and Staphylococcus aureus.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Flavone derivatives · Ampicillin · Pro-drug ester

Abstract

A new series of flavonyl pro-drug esters of ampicillin (Va-b) was prepared by condensing the appropriate bromomethyl flavone with ampicillin trihydrate potassium salt. Flavone derivatives and ampicillin both have good antibacterial activity. The synthesized compounds were tested for their antifungal and antibacterial activities in vitro. Both of the compounds were active against Candida krusei and Staphylococcus aureus.

Özet

A new series of flavonyl pro-drug esters of ampicillin (Va-b) was prepared by condensing the appropriate bromomethyl flavone with ampicillin trihydrate potassium salt. Flavone derivatives and ampicillin both have good antibacterial activity. The synthesized compounds were tested for their antifungal and antibacterial activities in vitro. Both of the compounds were active against Candida krusei and Staphylococcus aureus.

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Cite This Article

ÜNLÜSOY, M. C., ALTANLAR, N., ERTAN, R. (2005). Synthesis and Antimicrobial Activities of Some New Flavonyl Pro-drug Esters of Ampicillin. Turkish Journal of Chemistry, Cilt: 29 - Sayı: 2, 187–191. https://ajindex.com/articles/382206

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