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Journals / Turkish Journal of Chemistry / 2006 / Cilt: 30 - Sayı: 3

Synthesis and Antimicrobial Activity of Some New 3-Substituted Benzyl-5-(4-chloro-2-piperidin-1yl-thiazole-5-yl-methylene)-thiazolidine-2,4-dione Derivatives

Meltem Ceylan ÜNLÜSOY
Oya Bozdağ DÜNDAR
Pages
355–360
Publication Date
2006-03-01
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Compounds Va-b, Vd-f showed high activity against Escherichia coli comparable to ampicillin.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:A new series of thiazolyl thiazolidine-2,4-dione (Va-f) were synthesized and their structures were elucidated by IR, 1H-NMR, mass spectra and elementary analysis.
📊
Key Findings & Data:The synthesized compounds were tested for their antimicrobial activities against Candida albicans, Staphylococcus aureus, Bacillus subtilis and Escherichia coli.
💡
Conclusion & Impact:Compounds Va-b, Vd-f showed high activity against Escherichia coli comparable to ampicillin.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Thiazolidine-2 · 4-diones · thiazole derivatives

Abstract

A new series of thiazolyl thiazolidine-2,4-dione (Va-f) were synthesized and their structures were elucidated by IR, 1H-NMR, mass spectra and elementary analysis. The synthesized compounds were tested for their antimicrobial activities against Candida albicans, Staphylococcus aureus, Bacillus subtilis and Escherichia coli. Compounds Va-b, Vd-f showed high activity against Escherichia coli comparable to ampicillin.

Özet

A new series of thiazolyl thiazolidine-2,4-dione (Va-f) were synthesized and their structures were elucidated by IR, 1H-NMR, mass spectra and elementary analysis. The synthesized compounds were tested for their antimicrobial activities against Candida albicans, Staphylococcus aureus, Bacillus subtilis and Escherichia coli. Compounds Va-b, Vd-f showed high activity against Escherichia coli comparable to ampicillin.

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Cite This Article

ÜNLÜSOY, M. C., DÜNDAR, O. B. (2006). Synthesis and Antimicrobial Activity of Some New 3-Substituted Benzyl-5-(4-chloro-2-piperidin-1yl-thiazole-5-yl-methylene)-thiazolidine-2,4-dione Derivatives. Turkish Journal of Chemistry, Cilt: 30 - Sayı: 3, 355–360. https://ajindex.com/articles/218008

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