In all DVT patients having thrombosisin the distal and proximal leg veins, the mean malondialdehyde (MDA) levels significantly increased and the mean levels of vitamin Asignificantly decreased, compared to healthy controls (p 0.05).Conclusion: Our study results suggest that decreased vitamin A levels may play a role in the development of DVT.
📌 3 Key Takeaways
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Objective & Hypothesis:Objectives: This study aims to investigate the effect of deep venous thrombosis (DVT) on oxidative damage, vitamin A, and beta-carotenelevels.Patients and methods: A total of 50 DVT patients (29 females, 21 males; mean age 48 years; range, 20 to 75 years) who were admittedto the cardiovascular surgery clinic of Elazığ Training and Research Hospital with acute ( 0.05).
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Key Findings & Data:Objectives: This study aims to investigate the effect of deep venous thrombosis (DVT) on oxidative damage, vitamin A, and beta-carotenelevels.Patients and methods: A total of 50 DVT patients (29 females, 21 males; mean age 48 years; range, 20 to 75 years) who were admittedto the cardiovascular surgery clinic of Elazığ Training and Research Hospital with acute ( 0.05).
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Conclusion & Impact:In all DVT patients having thrombosisin the distal and proximal leg veins, the mean malondialdehyde (MDA) levels significantly increased and the mean levels of vitamin Asignificantly decreased, compared to healthy controls (p 0.05).Conclusion: Our study results suggest that decreased vitamin A levels may play a role in the development of DVT.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Özet
Objectives: This study aims to investigate the effect of deep venous thrombosis (DVT) on oxidative damage, vitamin A, and beta-carotenelevels.Patients and methods: A total of 50 DVT patients (29 females, 21 males; mean age 48 years; range, 20 to 75 years) who were admittedto the cardiovascular surgery clinic of Elazığ Training and Research Hospital with acute ( 0.05). In all DVT patients having thrombosisin the distal and proximal leg veins, the mean malondialdehyde (MDA) levels significantly increased and the mean levels of vitamin Asignificantly decreased, compared to healthy controls (p 0.05).Conclusion: Our study results suggest that decreased vitamin A levels may play a role in the development of DVT.
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Cite This Article
TÜRKER, F. S., MALBORA, A., ERİŞİR, M. (2020). The effect of deep venous thrombosis on oxidative damage and vitamin A and beta-carotene levels. Turkish journal of vascular surgery, Cilt: 29 - Sayı: 3, 189–195. https://ajindex.com/articles/375742
Naess IA, Christiansen SC, Romundstad P, Cannegieter SC, Rosendaal FR, Hammerstrøm J. Incidence and mortality of venous thrombosis: a population-based study. J Thromb Haemost 2007;5:692-9
Veeger NJ, Piersma-Wichers M, Tijssen JG, Hillege HL, van der Meer J. Individual time within target range in patients treated with vitamin K antagonists: main determinant of quality of anticoagulation and predictor of clinical outcome. A retrospective study of 2300 consecutive patients with venous thromboembolism. Br J Haematol 2005;128:513-9
McCully KS. Vascular pathology of homocysteinemia: implications for the pathogenesis of arteriosclerosis. Am J Pathol 1969;56:111-28
Lijfering WM, Rosendaal FR, Cannegieter SC. Risk factors for venous thrombosis - current understanding from an epidemiological point of view. Br J Haematol 2010;149:824-33
Lock K, Pomerleau J, Causer L, Altmann DR, McKee M. The global burden of disease attributable to low consumption of fruit and vegetables: implications for the global strategy on diet. Bull World Health Organ 2005;83:100-8
Myung SK, Ju W, Cho B, Oh SW, Park SM, Koo BK, et al. Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials. BMJ 2013;346:f10
Brøndum-Jacobsen P, Benn M, Tybjaerg-Hansen A, Nordestgaard BG. 25-Hydroxyvitamin D concentrations and risk of venous thromboembolism in the general population with 18,791 participants. J Thromb Haemost 2013;11:423-31
Glynn RJ, Ridker PM, Goldhaber SZ, Zee RY, Buring JE. Effects of random allocation to vitamin E supplementation on the occurrence of venous thromboembolism: report from the Women's Health Study. Circulation 2007;116:1497-503
Brodin E, Lerstad G, Grimnes G, Brækkan SK, Vik A, Brox J, et al. Serum levels of vitamin D are not associated with future risk of venous thromboembolism. The Tromsø Study. Thromb Haemost 2013;109:885-90
Bulger EM, Helton WS, Clinton CM, Roque RP, Garcia I, Maier RV. Enteral vitamin E supplementation inhibits the cytokine response to endotoxin. Arch Surg 1997;132:1337-41
Marchetti M, Vignoli A, Bani MR, Balducci D, Barbui T, Falanga A. All-trans retinoic acid modulates microvascular endothelial cell hemostatic properties. Haematologica 2003;88:895-905