SavedAdd your journal

Journals / Turkish journal of physical medicine and rehabilitation / 2018 / Cilt: 64 - Sayı: 1

Effect of vitamin D levels on radiographic knee osteoarthritis and functional status

Bedriye MERMERCİ BAŞKAN
Fatma GÜL YURDAKUL
Ezgi AYDIN
FİLİZ SİVAS
HATİCE BODUR
Pages
1–7
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There was no correlation between serum 25(OH)D levels and functional status.Conclusion: Our study results show that serum 25(OH)D level is not related to the severity of the radiographic knee OA grading or to thefunctional assessment.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objectives: This study aims to investigate the effect of serum levels of 25 hydroxyvitamin D (25(OH)D) in patients with primary kneeosteoarthritis (OA) and to assess its relationship with the radiographic grading and functional status.Patients and methods: Serum 25(OH)D levels were measured in 107 patients (90 females, 17 males; mean age 63.0±9.6 years; range, 40 to86 years) with primary knee OA.
📊
Key Findings & Data:Data including age, sex, disease duration, body mass index (BMI), and pain severity were recorded.Results: The mean 25(OH)D level was 13.4±10.6 ng/mL, and 90 patients (84.1%) had vitamin D deficiency.
💡
Conclusion & Impact:There was no correlation between serum 25(OH)D levels and functional status.Conclusion: Our study results show that serum 25(OH)D level is not related to the severity of the radiographic knee OA grading or to thefunctional assessment.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Objectives: This study aims to investigate the effect of serum levels of 25 hydroxyvitamin D (25(OH)D) in patients with primary kneeosteoarthritis (OA) and to assess its relationship with the radiographic grading and functional status.Patients and methods: Serum 25(OH)D levels were measured in 107 patients (90 females, 17 males; mean age 63.0±9.6 years; range, 40 to86 years) with primary knee OA. Radiographic grading was based on the Kellgren-Lawrence Grading Scale and the Osteoarthritis ResearchSociety International (OARSI) Atlas Grading Scale, while the functional status was assessed using the Lequesne indices and Turkish versionof the Knee Injury and Osteoarthritis Outcome Score-Physical Function Short-Form (KOOS-PS). Pain was evaluated using the Visual AnalogScale for Pain (VAS-Pain). Data including age, sex, disease duration, body mass index (BMI), and pain severity were recorded.Results: The mean 25(OH)D level was 13.4±10.6 ng/mL, and 90 patients (84.1%) had vitamin D deficiency. The presence of severe osteophyteswas observed in 67 patients (62.6%) and 85 patients (79.4%) had Grade 2-3 joint space narrowing (JSN). The mean KOOS-PS and Lequesnescores were 40.1±12.3 and 12.9±3.6, respectively. There was no correlation between serum 25(OH)D levels and functional status.Conclusion: Our study results show that serum 25(OH)D level is not related to the severity of the radiographic knee OA grading or to thefunctional assessment. Age and BMI are the factors affecting the radiological knee OA severity, while age, sex, BMI, and pain severity are themain determinants of the functional status.

🔖

Cite This Article

BAŞKAN, B. M., YURDAKUL, F. G., AYDIN, E., SİVAS, F., BODUR, H. (2018). Effect of vitamin D levels on radiographic knee osteoarthritis and functional status. Turkish journal of physical medicine and rehabilitation, Cilt: 64 - Sayı: 1, 1–7. https://ajindex.com/articles/375218

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (11)

  1. Samuels J, Krasnokutsky S, Abramson SB. Osteoarthritis: a tale of three tissues. Bull NYU Hosp Jt Dis 2008;66:244- 50. Kwan Tat S, Lajeunesse D, Pelletier JP, Martel-Pelletier J. Targeting subchondral bone for treating osteoarthritis: what is the evidence?Best Pract Res Clin Rheumatol 2010;24:51-70.
  2. Fidan F, Alkan BM, Tosun A. Pandemic era: Vitamin D deficiency and insufficiency. Turkish Journal of Osteoporosis 2014; 20:71-4.
  3. McAlindon TE, Felson DT, Zhang Y, Hannan MT, Aliabadi P, Weissman B, et al. Relation of dietary intake and serum levels of vitamin D to progression of osteoarthritis of the knee among participants in the Framingham Study. Ann Intern Med 1996;125:353-9.
  4. Heidari B, Heidari P, Hajian-Tilaki K. Association between serum vitamin D deficiency and knee osteoarthritis. Int Orthop 2011;35:1627-31.
  5. Al-Jarallah KF, Shehab D, Al-Awadhi A, Nahar I, Haider MZ, Moussa MA. Are 25(OH)D levels related to the severity of knee osteoarthritis and function? Med Princ Pract 2012;21:74-8.
  6. Felson DT, Niu J, Clancy M, Aliabadi P, Sack B, Guermazi A, et al. Low levels of vitamin D and worsening of knee osteoarthritis: results of two longitudinal studies. Arthritis Rheum 2007;56:129-36.
  7. Altman R, Asch E, Bloch D, Bole G, Borenstein D, Brandt K, et al. Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association. Arthritis Rheum 1986;29:1039-49.
  8. Kellgren JH, Lawrence JS. Radiological assessment of osteo- arthrosis. Ann Rheum Dis 1957;16:494-502.
  9. Altman RD, Hochberg M, Murphy WA Jr, Wolfe F, Lequesne M. Atlas of individual radiographic features in osteoarthritis. Osteoarthritis Cartilage 1995;3:3-70. D’Agostino MA, Conaghan P, Le Bars M, Baron G, Grassi W, Martin-Mola E, et al. EULAR report on the use of ultrasonography in painful knee osteoarthritis. Part 1: prevalence of inflammation in osteoarthritis. Ann Rheum Dis 2005;64:1703-9. Lequesne MG. The algofunctional indices for hip and knee osteoarthritis. J Rheumatol 1997;24:779-81.
  10. Gul ED, Yilmaz O, Bodur H. Reliability and validity of the Turkish version of the knee injury and osteoarthritis outcome score-physical function short-form (KOOS-PS). J Back Musculoskelet Rehabil 2013;26:461-6.
  11. Cherniack EP, Florez H, Roos BA, Troen BR, Levis S. Hypovitaminosis D in the elderly: from bone to brain. J Nutr Health Aging 2008;12:366-73. Holick MF. Vitamin D deficiency. N Eng