Journals / Turkish Journal of Family Medicine and Primary Care / 2015 / Cilt: 9 - Sayı: 1

Assesment of Etiologic Factors in Children With Attention Deficit Hyperactivity Disorder: Serum Levels of Boron and Selenium

Pages
6–9
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Deficiency in the level of selenium and boron entering into the structure of the antioxidant enzyme system can lead to ADHD and other psychiatric disorders by causing damage to the brain tissue related to free radicals.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: We aimed to determine the role of trace elements; selenium and boron levels in children and adolescents who have Attention Deficit Hyperactivity Disorder (ADHD).
📊
Key Findings & Data:Material-Method: The study group consisted of 30 children who were diagnosed as ADHD according to DSM-IV criteria and was compared with 20 healthy children who did not have ADHD.
💡
Conclusion & Impact:Deficiency in the level of selenium and boron entering into the structure of the antioxidant enzyme system can lead to ADHD and other psychiatric disorders by causing damage to the brain tissue related to free radicals.
🔬Design:Survey & Empirical Study
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: We aimed to determine the role of trace elements; selenium and boron levels in children and adolescents who have Attention Deficit Hyperactivity Disorder (ADHD). Material-Method: The study group consisted of 30 children who were diagnosed as ADHD according to DSM-IV criteria and was compared with 20 healthy children who did not have ADHD. The study and control groups were given to fill out a questionnaire which consists of 30 questions for screening sociodemographic data, age, gender, prenatal, natal and postnatal trauma history, having any toxic-metabolic condition or infection, familial history of ADHD and psychiatric disorders. Turgay s DSM-IV-Based Child and Adolescent Behavioral Disorders Screening and Rating Scale (T-DSM-IV-S), Conners Teacher Rating Scale, Conners Parent Rating Scale, Kiddie schedule for affective disorders and schizophrenia-present and lifetime version (K-SADS-PL), and Wechsler Intelligence Scale for Children-Revised (WISC-R) were used to diagnose ADHD. Serum selenium and boron levels were measured with the atomic absorption spectrophotometry. Result: All the scores of scales rating the ADHD symptoms of the children in the study group were significantly higher than in the control group. A statistically significant decrease in the serum selenium and boron levels was detected in children with ADHD. Conclusion: One of the important mechanisms in ADHD etiology is brain damage. Deficiency in the level of selenium and boron entering into the structure of the antioxidant enzyme system can lead to ADHD and other psychiatric disorders by causing damage to the brain tissue related to free radicals.

🔖

Cite This Article

ŞAFAK, E. D., MAZICIOĞLU, M. M., ŞAHİN, U., MISTIK, S., ÜSTÜNBAŞ, H. B. (2015). Assesment of Etiologic Factors in Children With Attention Deficit Hyperactivity Disorder: Serum Levels of Boron and Selenium. Turkish Journal of Family Medicine and Primary Care, Cilt: 9 - Sayı: 1, 6–9. https://ajindex.com/articles/374141

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. American Psychiatric Association, Diagnostic and Statistical Manual of Mental Disorders (DSM-IV), Washington, DC. American Psychiatric Press, 1994
  2. Faraone SV, Sergeant J, Gilberg C et al. The worldwide prevalence of ADHD: Is it an American condition? World Psychiatry 2003; 104–113
  3. Cheng K, Myers MK. Attention deficit hyperactivity disorder. In: Stubbe ED (eds) Child and Adolescent Psychiatry. Lippincott Williams &Wilkins, Philadelphia. 2005; pp: 53–73
  4. Burd L, Klug MG, Coumbe MJ et al. Children and adolescents with attention deficit-hyperactivity disorder: 1. Prevalence and cost of care. J Child Neurol 2003; 18(8):555–61
  5. Vasconcelos MM, Werner JJr, Malheiros AF et al. Attention-deficit/hyperactivity disorder prevalence in an inner city elementary school. Arq Neuropsiquiatr 2003; 61(1): 67–73
  6. Rube D, Reddy PD. Attention deficit hyperactivity disorder. In: Klykylo WM, Kay JL (ed). Clinical Child Psychiatry, Second Edition, Wiley 2005; pp: 153–191
  7. Ramaekers VT, Calomme M, Berghe V et al. Selenium deficiency triggering intractable seizures. Neuropediatrics 1994; 25; 217–223
  8. Weber GF, Maertens P, Meng XZ et al. Glutathione peroxidase deficiency and childhood seizures. Lancet 1991; 337:1443–44
  9. Penland JG. Dietary Boron, Brain Function, and Cognitive Performance. Environ Health Perspect 1994; 102(Suppl 7): 65–72
  10. Greenbaum AL. Micronutrient Mineral Deficiencies. In: Berhman ER, Kliegman MR, Jenson BH. Nelson Textbook of Pediatrics 18 th edition, Elsevier Science, Philedelphia, Pennsylvania 2007 pp. 265-67
  11. Bilgiç A, Türkoğlu S, Ozcan O et al. Relationship between anxiety, anxiety sensitivity and conduct disorder symptoms in children and adolescents with attention-deficit/hyperactivity disorder (ADHD). Eur Child Adolesc Psychiatry 2011; 22(9): 523-32
  12. Bellato AS, Gine MF, Menega´rio AA. “Determination of B in body fluids by isotope dilution inductively coupled mass spectrometry with direct injection nebulization”, Microchemical Journal, 2004; 77: 119–22
  13. Goulle J, Mahieu L, Castermant J et al. Metal and metalloid multi-elementary ICP-MS validation in whole blood, plasma, urine and hair: reference values. Forensic Science International 2005; 153: 39–44
  14. Oster O, Prellwitz W. Selenium and cardiovascular disease. Biol Trace Elem Research 1990; 24: 91-103
  15. Schweizer U, Brauer AU, Köhrle J, et al. Selenium and brain function: a poorly recognized liaison. Brain Research Reviews 2004; 45:164- 78
  16. Neve J. Selen