Journals / Turkish Journal of Family Medicine and Primary Care / 2020 / Cilt: 14 - Sayı: 4

Standard or Population Specific Skin Patch Test Series? Results of 615 patients with a pre-diagnosed of Allergic Contact Dermatitis

Standart Test mi, yoksa Popülasyona Özel Deri Yama Testi Serisi mi? Allerjik Kontakt Dermatit Ön Tanısı Alan 615 Hastanın Sonuçları

Pages
548–553
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion:Performing new skin patch tests with fewer allergens specific to the country and individuals, based on local experiences and patient history can reduce healthcare costs and new sensitizations ofthe patients in the diagnosis of ACD.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective:The incidence of allergic contact dermatitis (ACD) has increased especiallyin modern and urbanized communities in recent years, just like other allergic diseases.
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Key Findings & Data:Methods:A total of 615 patients’demographics data and patch test results were evaluated retrospectively.
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Conclusion & Impact:Conclusion:Performing new skin patch tests with fewer allergens specific to the country and individuals, based on local experiences and patient history can reduce healthcare costs and new sensitizations ofthe patients in the diagnosis of ACD.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective:The incidence of allergic contact dermatitis (ACD) has increased especiallyin modern and urbanized communities in recent years, just like other allergic diseases. The skin patch test is the gold standard test to identify allergens. The study aims to assess the results of patients who are considered to be diagnosed with ACD and underwent the European Standard Patch Test and compare them with other studies. Methods:A total of 615 patients’demographics data and patch test results were evaluated retrospectively. Chi-square and Fisher’s exact tests were used for statistical evaluation. Results:Of the 615 patients who underwent skin patch testing, 430 (70%) were female and 185 (30%) were male. The mean age was 40.4 ± 12.9 years. No positive reactions were detected in 483(78.6%) of 615 patients. Nickel sulfate (10.9%), balsam of Peru(3.9%), cobalt chloride (3.2%), potassium dichromate (%2.9) and methyldibromo glutaronitrile (%2.4) were the five most common allergens that caused ACD. Of the 30 allergens in the skin patch test series, 18 had a positive reaction rate was below 1%. Conclusion:Performing new skin patch tests with fewer allergens specific to the country and individuals, based on local experiences and patient history can reduce healthcare costs and new sensitizations ofthe patients in the diagnosis of ACD.

Özet

Amaç:Allerjik kontakt dermatit (AKD) insidansı, son yıllarda tıpkı diğer allerjik hastalıklar da olduğu gibi özellikle modern ve kentleşmiş topluluklarda artmıştır. Deri yama testi, allerjenleri belirlemek için altın standart testtir. Bu çalışmanın amacı, AKD tanısı düşünülen ve Avrupa Standart Seri Yama Testi uygulanan hastaların sonuçlarını değerlendirmektir. Yöntem:Toplam 615 hastanın demografik verileri ve yama testi sonuçları retrospektif olarak değerlendirilmiştir. İstatistiksel değerlendirme için, Ki-kare ve Fisher kesin testi (Fisher's exact test) kullanılmıştır. Bulgular:Deri yama testi yapılan 615 hastanın, 430'u (%70) kadın, 185'i (%30) erkekti. Hastaların yaş ortalaması 40.4 ± 12.9 yıl idi. 615 hastanın 483'ünde (% 78,6) pozitif reaksiyon saptanmamıştır. Nikel sülfat (% 10,9), Peru balsamı (%3,9), kobalt klorür (%3,2), potasyum dikromat (% 2,9) ve metildibromo glutaronitril (% 2,4) AKD'ye neden olan en yaygın beş allerjenolarak tespit edilmiştir. Deri yama testi serisinde bulunan 30 allerjenden 18’i %1'in altında pozitif reaksiyon vermiştir. Sonuç: AKD tanısı koyarken, ülke ve kişilere özel, bölgesel tecrübe ve hasta hikayesine dayalı, daha az allerjen içeren yeni deri yama testi serileri uygulamak, sağlık giderlerini ve hastalardaki yeni duyarlanmaları azaltabilieceği düşünülmektedir.

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Cite This Article

YEŞİLLİK, S. (2020). Standard or Population Specific Skin Patch Test Series? Results of 615 patients with a pre-diagnosed of Allergic Contact Dermatitis. Turkish Journal of Family Medicine and Primary Care, Cilt: 14 - Sayı: 4, 548–553. https://ajindex.com/articles/374121

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