Journals / Turkish Journal of Endocrinology and Metabolism / 2018 / Cilt: 22 - Sayı: 1

İki Farklı Büyüme Kriterine Göre Büyüyen ve Büyümeyen Benign Nodüllerin Sitolojik Karşılaştırması

Cytologic Comparison Between Growing and Non-growing Benign Thyroid Nodules Evaluated Using Two Different Growth Criteria

Pages
16–20
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: According to two different growth criteria, the growth of a benign nodule is not an additional risk factor for cancer

📌 3 Key Takeaways

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Objective & Hypothesis:Thyroid nodules are frequent in the adult population.
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Key Findings & Data:Material and Methods: We retrospectively reviewed thyroid fine-needle aspiration records of all patients at Dokuz Eylül University Hospital between January 2006 and June 2009.
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Conclusion & Impact:Conclusion: According to two different growth criteria, the growth of a benign nodule is not an additional risk factor for cancer
🔬Design:Review & Systematic Survey
📍Scope:2006 Verileri
⚙️Variables:Domain Parameters

Abstract

Thyroid nodules are frequent in the adult population. Thyroid fine-needle aspiration biopsy is performed for diagnosing cancerous nodules. It is suggested that biopsy-proven benign thyroid nodules should be followed up clinically, and if they grow, rebiopsy should be performed. However, certain growth criteria have not yet been defined. Material and Methods: We retrospectively reviewed thyroid fine-needle aspiration records of all patients at Dokuz Eylül University Hospital between January 2006 and June 2009. The nodules that underwent second biopsies were evaluated using two different growth criteria: at least 50% increase in the nodule maximal diameter and 20% increase in at least two nodule dimensions with a minimal increase of 2 mm. Results: From a total of 4217 thyroid nodules, we evaluated the cytological results of 117 benign thyroid nodules, which underwent follow-up biopsies. No significant difference was observed in the cytological results of the growing group (n:21), which had at least 50% increase in the maximal nodule diameter, and the non-growing group (n:96) (p=0.999). In addition, using the growth criteria of 20% increase in at least two nodule dimensions with a minimal increase of 2 mm, no significant difference was observed in the cytological results of the growing (n:47) and non-growing (n:70) benign thyroid nodules (p=0.700). Conclusion: According to two different growth criteria, the growth of a benign nodule is not an additional risk factor for cancer

Özet

Tiroid nodülü erişkinlerde sık görülür. Tiroid inceiğne aspirasyon biyopsisi tiroid nodülünde kanser varlığınıaraştırmak amaçlı kullanılır. Biyopsi ile benign olduklarısaptanan nodüllerin klinik olarak izlenmesi, büyüme tespitedildiğinde yeniden biyopsi alınması önerilmektedir. Fakatnet bir büyüme kriteri belirlenmemiştir.Gereç ve Yöntemler: Dokuz Eylül Üniversitesi Hastanesi'nde Ocak 2006-Haziran 2009 tarihleri arasında uygulanan TİİAB kayıtları geriye dönük olarak incelendi. İkincibir TİİAB yapılmış olan benign nodüllerin izlemdeki büyümeleri iki farklı büyüme kriteri kullanılarak (en büyüknodül çapında %50 ve ya üzerinde artış, nodülün en az ikiçapında -2 mm'den az olmamak üzere- %20 veya üzerinde artış) değerlendirildi.Bulgular: İnce iğne aspirasyon biyopsisi yapılan 4217 tiroid nodülden izlem biyopsileri olan benign nodüller incelemeye alındı. İzlemde maximum çapta %50 ve üzerindeartışa göre büyüyenle (n: 21), bu kritere göre büyümeyen(n:96) benign nodüller incelendiğinde aralarında anlamlısitolojik fark saptanmadı (p=0.999). Benzer şekilde nodülün en az iki çapında -iki mm'den az olmamak üzere%20 ve üzerinde boyut artışı saptanan nodüllerle (n:47),bu kritere göre büyümeyenler (n:70) arasında anlamlı sitolojik fark saptanmadı (p=0.700).Sonuç: Çalışmada kullanılan iki farklı büyüme kriterinegöre benign nodüllerin izlemde büyümesi kanser varlığıiçin ek risk oluşturmamıştır

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Cite This Article

YALÇIN, M. M. (2018). İki Farklı Büyüme Kriterine Göre Büyüyen ve Büyümeyen Benign Nodüllerin Sitolojik Karşılaştırması. Turkish Journal of Endocrinology and Metabolism, Cilt: 22 - Sayı: 1, 16–20. https://ajindex.com/articles/370859

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