Journals / Turkish Journal of Anaesthesiology and Reanimation / 2019 / Cilt: 47 - Sayı: 5

Postoperative Analgesic Efficacy of Preemptive and Postoperative Lornoxicam or Tramadol in Lumbar Disc Surgery

Pages
375–381
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Moreover, preemptive analgesia was quite effective in prevention and treatment of postoperative pain.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: To compare preemptive and postoperative analgesic efficacy of tramadol and lornoxicam administered before anaesthesia inductionin lumbar discectomy.Methods: This randomised, double-blind trial was conducted on 60 ASA I and II patients undergoing lumbar discectomy.
📊
Key Findings & Data:Group L (n=30)received 3×8 mg day-1 lornoxicam, and Group T (n=30) received 3×1.5 mg kg-1 day-1 tramadol.
💡
Conclusion & Impact:Moreover, preemptive analgesia was quite effective in prevention and treatment of postoperative pain.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Objective: To compare preemptive and postoperative analgesic efficacy of tramadol and lornoxicam administered before anaesthesia inductionin lumbar discectomy.Methods: This randomised, double-blind trial was conducted on 60 ASA I and II patients undergoing lumbar discectomy. Group L (n=30)received 3×8 mg day-1 lornoxicam, and Group T (n=30) received 3×1.5 mg kg-1 day-1 tramadol. A verbal rating scale (VRS), the duration ofeffective analgesia, the number of additional analgesics used, adverse effects and patient satisfaction were evaluated at the postoperative 30thminute and 1st, 2nd, 4th, 6th, 8th, 12th and 24th hours.Results: There were no significant differences between Groups L and T regarding demographic and clinical characteristics, the number ofadditional analgesics and the duration of effective analgesia, adverse effects and patient satisfaction. VRS scores of the patients in Group T weresignificantly higher than those in Group L at the postoperative 30th minute (p=0.050) and the 1st hour (p=0.005).Conclusion: Lornoxicam, which was used for preemptive and postoperative analgesia in lumbar disc surgery, had provided adequate and effective analgesia such as tramadol. Moreover, preemptive analgesia was quite effective in prevention and treatment of postoperative pain.

🔖

Cite This Article

COŞKUN, E., DİNÇER, E., TURAN, G., ÖZGÜLTEKİN, A. (2019). Postoperative Analgesic Efficacy of Preemptive and Postoperative Lornoxicam or Tramadol in Lumbar Disc Surgery. Turkish Journal of Anaesthesiology and Reanimation, Cilt: 47 - Sayı: 5, 375–381. https://ajindex.com/articles/370471

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (5)

  1. Rawal N. Postoperatif Ağrı Tedavisi. In: Erdine S, editor. Ağrı. İstanbul: Nobel Kitabevi; 2002.pp.118-35
  2. Dahl JB, Møiniche S. Pre-emptive analgesia. Br Med Bull 2004; 71: 13-27. [CrossRef] 3. Kehlet H. Controlling acute pain-role of preemptive analgesia, peripheral treatment, balanced analgesia and effects on outcome. In: Max M, editor. Pain 1999-An Updated Review. Seattle: IASP Press; 1999.pp.459-62
  3. Dahl JB, Kehlet H. Non-steroidal anti-inflammatory drugs: rationale for use in severe postoperative pain. Br J Anaesth 1991; 66: 703-12. [CrossRef] 5. Balfour JA, Fitton A, Barradell LB. Lornoxicam. A review of its pharmacology and therapeutic potential in the management of painful and inflammatory conditions. Drugs 1996; 51: 639-57. [CrossRef] 6. Pruss TP, Stroissnig H, Radhofer-Welte S, Wendtlandt W, Mehdi N, Takacs F, et al. Overview of the pharmacological properties, pharmacokinetics and animal safety assessment of lornoxicam. Postgrad Med J 1990; 66(Suppl 4): S18-21
  4. Nørholt SE, Sindet-Pedersen S, Larsen U, Bang U, Ingerslev J, Nielsen O, et al. Pain control after dental surgery: a double-blind, randomised trial of lornoxicam versus morphine. Pain 1996; 67: 335-43. [CrossRef] 8. Rosenow DE, Krieken F van, Stolke D, Kursten FW. Intravenous administration of lornoxicam, a new NSAID, and pethidine for postoperative pain. Clin Drug Investig 1996; 11: 11-9. [CrossRef] 9. Grond S, Sablotzki A. Clinical pharmacology of tramadol. Clin Pharmacokinet 2004; 43: 879-923. [CrossRef] 10. Houmes RJ, Voets MA, Verkaaik A, Erdmann W, Lachmann B. Efficacy and safety of tramadol versus morphine for moderate and severe postoperative pain with special regard to respiratory depression. Anesth Analg 1992; 74: 510-4. [CrossRef] 11. Aguilar JL, Rincón R, Domingo V, Espachs P, Preciado MJ, Vidal F. Absence of an early pre-emptive effect after thoracic extradural bupivacaine in thoracic surgery. Br J Anaesth 1996; 76: 72-6. [CrossRef] 12. Katz J. Pre-emptive analgesia: importance of timing. Can J Anaesth 2001; 48: 105-14. [CrossRef] 13. Olmez G, Kaya S, Aflay U, Sahin H. Comparison of lornoxicam versus tramadol analgesia for transrectal prostate biopsy: a randomized prospective study. Int Urol Nephrol 2008; 40: 341-4. [CrossRef] 14. Işik B, Arslan M, Ozsoylar O, Akçabay M. Effects of preoperative lornoxicam versus tramadol on postoperative pain and adverse effects in adult tonsillectomy patients. Agri 2009; 21: 113-20
  5. Güler A, Çelebioğlu B, Şahin A, Beksaç S. Co